ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-28.PDB
Scoring matrix: NBP2_1SEM-28_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.36
Foldx random average score for Saccharomyces cerevisiae: 19.709

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1546616
Proteins after disorder filtering: 4259
 Total fragments: 61691
Proteins after pattern filtering: 2022
 Total fragments: 10194
Proteins after MINT filtering: 8
 Total fragments: 108


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.36

-2.00

0.00

Best peptides

RRKRRPWPHR

0.00

-10.43

-8.43

         
Interactors      
Q01389

SRTEPSTPSR

12.12

-7.31

-5.31

SPSYPSIFRR

12.59

-7.92

-5.92

KRSKPLPPQL

13.17

-9.29

-7.29

P53933

RVAPPPLPNR

10.40

-13.97

-11.98

RPPPPPIPST

12.59

-9.42

-7.42

PPPPIPSTQK

15.34

-7.59

-5.59

P53914

KNVKPLPPKE

16.39

-7.86

-5.87

VKPLPPKEDD

16.87

-8.61

-6.61

PPIDPKDGGR

17.05

-7.27

-5.27

P48562

LNPYRPHHNM

13.90

-7.75

-5.75

MRQAPKRPDA

14.72

-8.46

-6.47

RTAPKPPISA

15.15

-8.55

-6.56

Q03497

LPPIPPTKSK

11.64

-8.16

-6.17

KPSKPEAKSK

12.37

-8.61

-6.61

QTHAPTTPNR

14.10

-6.84

-4.84

Q12469

RLAPSAPATK

13.34

-9.75

-7.75

KPFPRPSDDD

16.23

-5.85

-3.85

HRLAPSAPAT

17.00

-7.67

-5.67

P25293

PHNTPASVLN

19.07

-6.14

-4.14

PTPHNTPASV

19.12

-5.73

-3.74

P08018

RAPRRPLSTQ

11.87

-11.25

-9.25

APRRPLSTQH

15.69

-9.69

-7.69

GPPPRLPSDK

15.83

-7.14

-5.14

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER