ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-26.PDB
Scoring matrix: NBP2_1SEM-26_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.19
Foldx random average score for Saccharomyces cerevisiae: 13.872

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1372672
Proteins after disorder filtering: 4129
 Total fragments: 59413
Proteins after pattern filtering: 2111
 Total fragments: 14571
Proteins after MINT filtering: 8
 Total fragments: 160


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.19

-2.07

0.00

Best peptides

RRRHRRRRW

0.00

-11.22

-9.15

         
Interactors      
Q01389

RRYPQTPSY

9.58

-7.71

-5.64

KRSKPLPPQ

9.59

-5.69

-3.62

RSKPLPPQL

9.84

-6.12

-4.05

P53933

RRRPPPPPI

7.96

-7.31

-5.24

RTRRRPPPP

8.55

-8.98

-6.91

TRRRPPPPP

9.00

-7.32

-5.25

P53914

KNVKPLPPK

8.30

-7.24

-5.17

KPLPPKEDD

11.57

-4.25

-2.18

NVKPLPPKE

12.31

-4.97

-2.90

P48562

PLNPYRPHH

7.35

-9.67

-7.60

RQAPKRPDA

7.44

-10.36

-8.29

NGQFPRGPM

8.37

-7.21

-5.14

Q03497

KFIPSRPAP

6.63

-10.38

-8.31

HKPKVKPSK

7.48

-7.19

-5.12

KVKPSKPEA

8.84

-7.32

-5.25

Q12469

LKPFPRPSD

7.24

-8.50

-6.43

ELKPFPRPS

9.60

-6.89

-4.82

PHRLAPSAP

12.77

-3.91

-1.84

P25293

PTPHNTPAS

12.50

-5.81

-3.74

P08018

TQHPTRPNV

8.07

-7.02

-4.95

DGPPPRLPS

8.33

-8.90

-6.83

GPPPRLPSD

10.34

-8.24

-6.17

 


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