ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-2.PDB
Scoring matrix: NBP2_1SEM-2_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.07
Foldx random average score for Saccharomyces cerevisiae: 19.720

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1508007
Proteins after disorder filtering: 4517
 Total fragments: 98037
Proteins after pattern filtering: 2297
 Total fragments: 21549
Proteins after MINT filtering: 8
 Total fragments: 196


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.07

6.11

0.00

Best peptides

MLPRPFRRMR

0.00

-4.57

-10.68

         
Interactors      
Q01389

SPSYPSIFRR

10.35

-4.91

-11.02

EPSTPSRPVP

10.85

-5.29

-11.40

APKREAPKPP

11.07

-4.96

-11.07

P53933

VRTRRRPPPP

10.39

-4.38

-10.49

TRRRPPPPPI

10.51

-4.36

-10.47

RRRPPPPPIP

11.46

-3.89

-10.00

P53914

LPPIDPKDGG

13.29

-3.05

-9.16

AKNVKPLPPK

14.01

-3.31

-9.42

NVKPLPPKED

15.17

-2.34

-8.45

P48562

SPLNPYRPHH

9.21

-6.71

-12.82

NPYRPHHNMI

10.20

-4.68

-10.79

PPISAPRAPY

10.47

-4.92

-11.03

Q03497

HKQHKPKVKP

11.20

-3.90

-10.01

IPSRPAPKPP

11.60

-6.33

-12.44

LPPIPPTKSK

11.64

-3.46

-9.57

Q12469

RPHRLAPSAP

12.63

-4.90

-11.01

ELKPFPRPSD

13.13

-3.29

-9.40

RLAPSAPATK

13.24

-1.84

-7.95

P25293

APTPHNTPAS

16.26

-2.10

-8.21

TPHNTPASVL

16.37

-1.71

-7.82

NAPTPHNTPA

17.29

-0.81

-6.92

P08018

HPTRPNVAPH

9.85

-5.87

-11.98

PLSTQHPTRP

11.29

-4.71

-10.82

PPPRLPSDKF

12.38

-4.45

-10.56

 


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