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Matrix information:
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ADAN-name: NBP2_1SEM-19.PDB
Scoring matrix: NBP2_1SEM-19_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 22.85
Foldx random average score for Saccharomyces cerevisiae: 21.063 Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
Proteins belonging to other specie: 0
Nš of interactions described: 20
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1255282
Proteins after disorder filtering: 4445
Total fragments: 63983
Proteins after pattern filtering: 2011
Total fragments: 8310
Proteins after MINT filtering: 7
Total fragments: 80
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
22.85
|
-0.97 |
0.00 |
| Best peptides |
RRFRMGHHF |
0.00
|
-4.14 |
-3.17 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q01389 |
RPVPPDSSY |
12.89
|
-7.30 |
-6.33 |
|
RRYPQTPSY |
13.97
|
-7.21 |
-6.24 |
|
RTEPSTPSR |
16.32
|
-6.82 |
-5.85 |
| P53933 |
PPLPNRQLP |
17.38
|
-6.18 |
-5.21 |
|
PPIPSTQKP |
18.73
|
-6.83 |
-5.86 |
|
RTRRRPPPP |
19.77
|
-9.58 |
-8.61 |
| P53914 |
KNVKPLPPK |
18.96
|
-5.22 |
-4.25 |
|
KPLPPKEDD |
19.48
|
-3.25 |
-2.28 |
|
PIDPKDGGR |
20.91
|
-4.18 |
-3.21 |
| P48562 |
NPYRPHHNM |
12.87
|
-8.14 |
-7.17 |
|
PLNPYRPHH |
15.60
|
-3.59 |
-2.62 |
|
MRQAPKRPD |
17.32
|
-5.21 |
-4.24 |
| Q03497 |
IPSRPAPKP |
14.91
|
-10.25 |
-9.28 |
|
PPIPPTKSK |
15.71
|
-6.82 |
-5.85 |
|
KQHKPKVKP |
16.44
|
-7.53 |
-6.56 |
| P08018 |
APRRPLSTQ |
15.22
|
-8.33 |
-7.36 |
|
TRPNVAPHK |
15.88
|
-2.32 |
-1.35 |
|
PRLPSDKFS |
18.35
|
-3.83 |
-2.86 |
| Q12469 |
RLAPSAPAT |
18.60
|
-3.80 |
-2.83 |
|
LKPFPRPSD |
20.04
|
-4.63 |
-3.66 |
|
PSAPATKNH |
20.19
|
-2.86 |
-1.89 |
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