ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1SEM-11.PDB
Scoring matrix: NBP2_1SEM-11_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.85
Foldx random average score for Saccharomyces cerevisiae: 13.219

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1370783
Proteins after disorder filtering: 4526
 Total fragments: 70145
Proteins after pattern filtering: 2035
 Total fragments: 8803
Proteins after MINT filtering: 7
 Total fragments: 89


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.85

-0.67

0.00

Best peptides

RRKRHPR

0.00

-9.66

-8.99

         
Interactors      
Q01389

YPQTPSY

8.85

-6.76

-6.09

RRYPQTP

9.10

-6.45

-5.78

EPSTPSR

9.48

-5.10

-4.43

P53933

RRRPPPP

7.01

-9.15

-8.48

RRPPPPP

7.25

-7.41

-6.74

PPPLPNR

8.50

-7.14

-6.47

P53914

VKPLPPK

8.52

-6.31

-5.64

LPPIDPK

10.53

-4.68

-4.01

NVKPLPP

12.01

-3.80

-3.13

P48562

RGPMHPN

8.04

-6.97

-6.30

KPPISAP

8.96

-5.34

-4.67

NPYRPHH

8.97

-7.35

-6.68

Q03497

IPSRPAP

8.16

-7.71

-7.04

FPSKNPL

8.50

-6.47

-5.80

KPSKPEA

9.13

-6.71

-6.04

P08018

RAPRRPL

7.67

-9.35

-8.68

APRRPLS

9.93

-6.69

-6.02

HPTRPNV

9.94

-9.60

-8.93

Q12469

LKPFPRP

9.73

-5.98

-5.31

PFPRPSD

11.85

-6.10

-5.43

KPFPRPS

12.10

-4.72

-4.05

 


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