ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-7.PDB
Scoring matrix: NBP2_1GCQ-7_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 16.59
Foldx random average score for Saccharomyces cerevisiae: 12.388

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1201039
Proteins after disorder filtering: 4318
 Total fragments: 54792
Proteins after pattern filtering: 2013
 Total fragments: 10859
Proteins after MINT filtering: 7
 Total fragments: 117


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

16.59

-2.60

0.00

Best peptides

KRKRPRRW

0.00

-7.65

-5.05

         
Interactors      
Q01389

KRSKPLPP

7.84

-6.56

-3.96

KPLPPQLL

8.53

-7.14

-4.54

SPSYPSIF

9.38

-6.43

-3.83

P53933

RRPPPPPI

7.60

-7.50

-4.90

RRRPPPPP

8.32

-7.91

-5.31

TRRRPPPP

8.36

-8.37

-5.77

P53914

KPLPPKED

9.08

-5.78

-3.18

KNVKPLPP

9.60

-6.39

-3.79

VKPLPPKE

9.75

-7.98

-5.38

P48562

QFPRGPMH

7.20

-7.67

-5.07

MRQAPKRP

7.46

-7.27

-4.67

SPLNPYRP

9.00

-5.95

-3.35

Q03497

IPSRPAPK

8.08

-4.87

-2.27

HKPKVKPS

8.60

-5.44

-2.84

GKFIPSRP

8.63

-7.36

-4.76

P08018

RAPRRPLS

8.68

-6.58

-3.98

STQHPTRP

9.32

-7.26

-4.66

TRPNVAPH

9.69

-3.70

-1.10

Q12469

ELKPFPRP

6.88

-6.41

-3.81

LKPFPRPS

10.02

-7.08

-4.48

KPFPRPSD

10.09

-4.49

-1.89

 


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