ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-29.PDB
Scoring matrix: NBP2_1GCQ-29_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.64
Foldx random average score for Saccharomyces cerevisiae: 15.620

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1377466
Proteins after disorder filtering: 4116
 Total fragments: 54866
Proteins after pattern filtering: 1963
 Total fragments: 10135
Proteins after MINT filtering: 8
 Total fragments: 120


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.64

-0.94

0.00

Best peptides

RYRPRRPYFH

0.00

-15.34

-14.40

         
Interactors      
Q01389

RYPQTPSYYY

9.51

-10.52

-9.58

RSKPLPPQLL

11.11

-9.24

-8.30

ASPSYPSIFR

11.15

-9.79

-8.85

P53933

APPPLPNRQL

10.85

-11.90

-10.97

PPLPNRQLPN

11.20

-8.37

-7.43

RTRRRPPPPP

11.29

-13.71

-12.78

P53914

AKNVKPLPPK

11.86

-8.19

-7.25

NVKPLPPKED

12.18

-10.19

-9.25

PLPPKEDDEL

13.30

-6.71

-5.78

P48562

PYRPHHNMIN

6.98

-12.04

-11.10

ISAPRAPYPS

8.91

-11.15

-10.22

LNPYRPHHNM

9.40

-13.09

-12.15

Q03497

SFPSKNPLKN

9.70

-9.25

-8.31

KPKVKPSKPE

10.35

-7.43

-6.49

FIPSRPAPKP

11.46

-11.42

-10.48

Q12469

KPFPRPSDDD

12.21

-9.37

-8.43

LKPFPRPSDD

12.71

-6.95

-6.02

ELKPFPRPSD

12.86

-8.50

-7.56

P25293

NAPTPHNTPA

15.20

-4.64

-3.70

P08018

GPPPRLPSDK

9.93

-8.82

-7.88

RAPRRPLSTQ

11.65

-10.63

-9.70

PRRPLSTQHP

11.75

-13.19

-12.25

 


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