ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-26.PDB
Scoring matrix: NBP2_1GCQ-26_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.72
Foldx random average score for Saccharomyces cerevisiae: 13.547

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1345010
Proteins after disorder filtering: 4363
 Total fragments: 74429
Proteins after pattern filtering: 2187
 Total fragments: 15423
Proteins after MINT filtering: 8
 Total fragments: 155


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.72

-2.03

0.00

Best peptides

DRRKRRSPK

0.00

-8.82

-6.79

         
Interactors      
Q01389

SSSPPPIPK

8.09

-5.69

-3.66

PSYPSIFRR

8.67

-7.33

-5.30

RSKPLPPQL

9.16

-7.10

-5.07

P53933

RRRPPPPPI

7.43

-7.54

-5.51

RTRRRPPPP

7.73

-6.52

-4.49

TRRRPPPPP

7.92

-8.03

-6.00

P53914

KNVKPLPPK

6.13

-6.13

-4.10

NVKPLPPKE

12.03

-5.90

-3.87

PIDPKDGGR

13.37

-4.30

-2.27

P48562

PLNPYRPHH

6.48

-10.93

-8.90

THVQPVAPK

8.55

-3.54

-1.51

NGQFPRGPM

8.90

-7.00

-4.97

Q03497

HKPKVKPSK

5.41

-6.56

-4.53

KFIPSRPAP

7.61

-9.65

-7.62

PLPPIPPTK

7.83

-7.15

-5.12

Q12469

ELKPFPRPS

9.42

-7.67

-5.64

LKPFPRPSD

9.57

-9.49

-7.46

PHRLAPSAP

11.17

-6.97

-4.94

P25293

PTPHNTPAS

13.42

-6.11

-4.08

APTPHNTPA

13.53

-3.45

-1.42

P08018

PPPRLPSDK

7.77

-6.22

-4.19

PTRPNVAPH

8.35

-7.95

-5.92

APRRPLSTQ

8.51

-6.25

-4.22

 


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