ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-23.PDB
Scoring matrix: NBP2_1GCQ-23_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 20.33
Foldx random average score for Saccharomyces cerevisiae: 16.371

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1227189
Proteins after disorder filtering: 4559
 Total fragments: 63451
Proteins after pattern filtering: 1998
 Total fragments: 9827
Proteins after MINT filtering: 7
 Total fragments: 108


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

20.33

-2.10

0.00

Best peptides

WRMRRRM

0.00

-12.82

-10.72

         
Interactors      
Q01389

KPLPPQL

10.62

-7.02

-4.92

PSTPSRP

10.77

-6.57

-4.47

TPSRPVP

11.62

-6.83

-4.73

P53933

PPLPNRQ

10.06

-7.46

-5.36

RRRPPPP

10.25

-7.77

-5.67

RPPPPPI

12.15

-6.82

-4.72

P53914

KPLPPKE

11.53

-6.78

-4.68

NVKPLPP

15.23

-4.93

-2.83

P48562

QFPRGPM

9.71

-6.14

-4.04

SAPRAPY

10.51

-5.18

-3.08

NPYRPHH

10.66

-4.88

-2.78

Q03497

KFIPSRP

9.40

-8.36

-6.26

IPSRPAP

10.61

-5.04

-2.94

QPLPPIP

11.61

-6.98

-4.88

P08018

RAPRRPL

7.45

-10.41

-8.31

HPTRPNV

7.47

-5.85

-3.75

APRRPLS

9.01

-4.50

-2.40

Q12469

PFPRPSD

12.04

-3.65

-1.55

LKPFPRP

12.94

-6.01

-3.91

KPFPRPS

13.73

-5.41

-3.31

 


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