ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-18.PDB
Scoring matrix: NBP2_1GCQ-18_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 21.12
Foldx random average score for Saccharomyces cerevisiae: 19.517

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1491641
Proteins after disorder filtering: 4578
 Total fragments: 101503
Proteins after pattern filtering: 2248
 Total fragments: 14221
Proteins after MINT filtering: 8
 Total fragments: 114


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

21.12

1.25

0.00

Best peptides

FHRLKSIRHW

0.00

-1.27

-2.52

         
Interactors      
Q01389

APTKPNPQGH

15.14

-3.98

-5.23

REAPKPPANT

15.22

0.27

-0.98

TEPSTPSRPV

15.34

-3.17

-4.42

P53933

YNDLPMELPH

13.17

-4.01

-5.26

RRPPPPPIPS

13.67

-4.98

-6.23

KRVAPPPLPN

14.42

-5.04

-6.29

P53914

VKPLPPKEDD

12.04

-3.14

-4.39

LPPIDPKDGG

14.11

-3.76

-5.01

AKNVKPLPPK

15.24

-2.77

-4.02

P48562

PSPLNPYRPH

10.43

-4.65

-5.90

LNPYRPHHNM

10.63

-1.57

-2.82

TMRQAPKRPD

11.59

-4.46

-5.71

Q03497

FPSKNPLKNS

9.48

-4.17

-5.42

KKSFPSKNPL

11.66

-4.18

-5.43

KQHKPKVKPS

12.38

-5.27

-6.52

Q12469

LKPFPRPSDD

13.28

0.90

-0.35

PHRLAPSAPA

14.34

-5.21

-6.46

PFPRPSDDDY

14.68

2.00

0.75

P25293

NAPTPHNTPA

16.36

-0.55

-1.80

P08018

LSTQHPTRPN

12.39

-3.36

-4.61

PPRLPSDKFS

12.78

-3.64

-4.89

HPTRPNVAPH

15.32

-2.80

-4.05

 


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