ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-15.PDB
Scoring matrix: NBP2_1GCQ-15_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 21.77
Foldx random average score for Saccharomyces cerevisiae: 15.647

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1306076
Proteins after disorder filtering: 4013
 Total fragments: 42341
Proteins after pattern filtering: 1606
 Total fragments: 4694
Proteins after MINT filtering: 8
 Total fragments: 56


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

21.77

-1.52

0.00

Best peptides

RRWRRHRDR

0.00

-13.05

-11.53

         
Interactors      
Q01389

RTEPSTPSR

10.91

-9.20

-7.68

SPSYPSIFR

11.73

-7.03

-5.51

KRSKPLPPQ

12.50

-7.53

-6.01

P53933

VAPPPLPNR

12.55

-6.60

-5.08

RTRRRPPPP

14.31

-10.18

-8.66

SYPGNPTSR

14.77

-4.07

-2.55

P53914

KNVKPLPPK

13.54

-6.36

-4.84

PIDPKDGGR

13.95

-3.38

-1.86

LPPIDPKDG

14.39

-5.76

-4.24

P48562

NPYRPHHNM

7.53

-11.70

-10.18

SPSPLNPYR

10.88

-6.98

-5.46

RQAPKRPDA

11.82

-10.21

-8.69

Q03497

HKPKVKPSK

11.11

-7.40

-5.88

FPSKNPLKN

12.40

-6.95

-5.43

THAPTTPNR

12.87

-5.08

-3.56

Q12469

LKPFPRPSD

13.98

-4.39

-2.87

P25293

NAPTPHNTP

15.52

-6.51

-4.99

P08018

APRRPLSTQ

10.32

-10.22

-8.70

PPPRLPSDK

11.53

-9.80

-8.28

HPTRPNVAP

11.73

-10.90

-9.38

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER