ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-12.PDB
Scoring matrix: NBP2_1GCQ-12_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.72
Foldx random average score for Saccharomyces cerevisiae: 9.146

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1388882
Proteins after disorder filtering: 4487
 Total fragments: 62534
Proteins after pattern filtering: 2080
 Total fragments: 11351
Proteins after MINT filtering: 7
 Total fragments: 114


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.72

-1.88

0.00

Best peptides

RWIMKRWR

0.00

-6.85

-4.97

         
Interactors      
Q01389

PSYPSIFR

4.95

-4.67

-2.79

SSPPPIPK

6.40

-4.00

-2.12

PSTPSRPV

6.79

-5.36

-3.48

P53933

RRRPPPPP

5.79

-5.36

-3.48

TRRRPPPP

6.42

-4.74

-2.86

VSYPGNPT

6.55

-4.12

-2.24

P53914

KNVKPLPP

6.19

-5.94

-4.06

NVKPLPPK

6.92

-4.19

-2.31

KPLPPKED

7.42

-4.96

-3.08

P48562

PYRPHHNM

5.61

-5.36

-3.48

IGPAPRPP

5.75

-5.93

-4.05

RQAPKRPD

5.90

-5.94

-4.06

Q03497

KFIPSRPA

2.60

-8.10

-6.22

KVKPSKPE

5.98

-4.33

-2.45

KSFPSKNP

6.26

-4.43

-2.55

P08018

TQHPTRPN

5.57

-6.85

-4.97

DGPPPRLP

5.82

-5.88

-4.00

GPPPRLPS

7.52

-5.62

-3.74

Q12469

LKPFPRPS

5.26

-6.30

-4.42

ELKPFPRP

7.62

-4.34

-2.46

KPFPRPSD

7.71

-4.70

-2.82

 


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