ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-11.PDB
Scoring matrix: NBP2_1GCQ-11_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.97
Foldx random average score for Saccharomyces cerevisiae: 12.522

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1371706
Proteins after disorder filtering: 4619
 Total fragments: 84323
Proteins after pattern filtering: 2176
 Total fragments: 12373
Proteins after MINT filtering: 8
 Total fragments: 119


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.97

-1.73

0.00

Best peptides

RRKRHPH

0.00

-7.19

-5.46

         
Interactors      
Q01389

TPSRPVP

7.95

-5.24

-3.51

APKPPAN

8.45

-5.27

-3.54

FPNLTPN

8.47

-5.83

-4.10

P53933

RRPPPPP

5.10

-7.19

-5.46

RRRPPPP

5.24

-7.27

-5.54

RPPPPPI

6.40

-9.30

-7.57

P53914

VKPLPPK

9.03

-6.13

-4.40

KPLPPKE

9.83

-5.46

-3.73

NVKPLPP

10.48

-5.06

-3.33

P48562

NPYRPHH

4.58

-9.32

-7.59

RGPMHPN

6.26

-5.29

-3.56

FPRGPMH

7.60

-5.57

-3.84

Q03497

FPSKNPL

6.76

-5.64

-3.91

IPSRPAP

6.96

-8.93

-7.20

RPAPKPP

8.34

-5.60

-3.87

Q12469

PFPRPSD

9.68

-4.17

-2.44

LKPFPRP

9.78

-6.22

-4.49

KPFPRPS

10.34

-4.85

-3.12

P25293

PTPHNTP

10.16

-4.38

-2.65

PHNTPAS

12.14

-3.56

-1.83

TPHNTPA

12.46

-3.00

-1.27

P08018

RAPRRPL

5.62

-7.72

-5.99

RPNVAPH

7.18

-5.40

-3.67

HPTRPNV

7.62

-8.41

-6.68

 


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