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Matrix information:
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ADAN-name: MYO5_1ZUY-8.PDB
Scoring matrix: MYO5_1ZUY-8_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.2
Foldx random average score for Saccharomyces cerevisiae: 8.319 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1646266
Proteins after disorder filtering: 4606
Total fragments: 86074
Proteins after pattern filtering: 2212
Total fragments: 10746
Proteins after MINT filtering: 45
Total fragments: 560 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
10.20
|
0.04 |
0.00 |
| Best peptides |
RKMPLMDW |
0.00
|
-0.61 |
-0.65 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PNEPLLPP |
3.93
|
-3.95 |
-3.99 |
|
EPLLPPLP |
6.38
|
-3.58 |
-3.62 |
|
PLLPPLPG |
6.63
|
-2.61 |
-2.65 |
| P39113 |
PRRPQKNR |
4.87
|
-2.45 |
-2.49 |
|
HRGPRRPQ |
5.71
|
-2.24 |
-2.28 |
|
AMSPLGAP |
5.85
|
-2.44 |
-2.48 |
| P40073 |
YPQQQPSH |
6.67
|
-2.76 |
-2.80 |
| P25604 |
PKSPHLKP |
5.09
|
-1.74 |
-1.78 |
|
PPLPPPPP |
5.47
|
-3.96 |
-4.00 |
|
PPKPKSPH |
5.53
|
-1.14 |
-1.18 |
| P25623 |
KPLPVEPA |
6.57
|
-1.53 |
-1.57 |
|
PPLQPQSK |
7.20
|
-1.35 |
-1.39 |
|
SDTPPLPP |
7.43
|
-0.68 |
-0.72 |
| Q05933 |
PGFPLNNV |
6.34
|
-1.57 |
-1.61 |
|
PVDPNTDR |
6.80
|
-0.31 |
-0.35 |
|
FRGPAYPS |
7.76
|
-0.50 |
-0.54 |
| P53094 |
YPLKLPPL |
3.95
|
-4.26 |
-4.30 |
|
LKLPPLPL |
5.00
|
-1.70 |
-1.74 |
|
LNVPLPPQ |
5.28
|
-3.50 |
-3.54 |
| Q12451 |
HLLPWLPP |
5.20
|
-3.56 |
-3.60 |
|
APKHAPPP |
6.47
|
-3.20 |
-3.24 |
|
QPHLLPWL |
6.53
|
-2.11 |
-2.15 |
| P15891 |
KKEPVKTP |
5.19
|
-3.16 |
-3.20 |
|
TPEKKPKE |
5.39
|
-3.66 |
-3.70 |
|
VKTPSPAP |
5.55
|
-1.73 |
-1.77 |
| P48562 |
SPSPLNPY |
4.22
|
-2.93 |
-2.97 |
|
PLNPYRPH |
5.57
|
-0.78 |
-0.82 |
|
GQFPRGPM |
5.60
|
-1.36 |
-1.40 |
| P40341 |
SRNIPPPP |
5.03
|
-3.06 |
-3.10 |
|
PPLNDPSN |
6.96
|
-2.03 |
-2.07 |
|
RNIPPPPP |
7.14
|
-2.80 |
-2.84 |
| Q08912 |
PKGPPPPP |
6.00
|
-2.73 |
-2.77 |
|
HPKGPPPP |
6.45
|
-3.28 |
-3.32 |
|
CYTPSWGP |
7.24
|
-0.96 |
-1.00 |
| P17555 |
PPRPKKPS |
6.25
|
-1.71 |
-1.75 |
|
APAPPPPP |
6.29
|
-3.73 |
-3.77 |
|
PKKPSTLK |
6.67
|
-0.47 |
-0.51 |
| Q12342 |
AKAPPPPP |
5.41
|
-3.70 |
-3.74 |
|
KAKAPPPP |
6.86
|
-3.50 |
-3.54 |
| P47068 |
PPLPRAPP |
5.41
|
-3.24 |
-3.28 |
|
LPEPISPE |
5.68
|
-2.20 |
-2.24 |
|
DPSSNPFF |
5.74
|
-1.95 |
-1.99 |
| P38822 |
APEVPPPR |
4.80
|
-3.90 |
-3.94 |
|
PEVPPPRR |
6.80
|
-1.75 |
-1.79 |
|
TPTTTPGS |
7.56
|
-1.98 |
-2.02 |
| P04050 |
TCLPVPPP |
6.16
|
-3.80 |
-3.84 |
|
PVRPSISF |
6.43
|
-1.25 |
-1.29 |
|
SPAYSPKQ |
6.94
|
-2.18 |
-2.22 |
| P40450 |
PQLPPPPP |
5.37
|
-3.24 |
-3.28 |
|
PPLPDLFK |
5.61
|
-2.31 |
-2.35 |
|
LPQLPPPP |
6.36
|
-3.94 |
-3.98 |
| P40453 |
RKRPPPPP |
4.61
|
-3.14 |
-3.18 |
|
PDLPIRLR |
5.48
|
-1.20 |
-1.24 |
|
LRKRPPPP |
5.74
|
-3.32 |
-3.36 |
| Q12168 |
DPYFPQFR |
6.13
|
-1.70 |
-1.74 |
|
HPVPKPNI |
6.25
|
-3.01 |
-3.05 |
|
NDDPYFPQ |
6.34
|
-1.49 |
-1.53 |
| P41832 |
SPAPPPPP |
6.43
|
-3.76 |
-3.80 |
|
PPAPPMMP |
6.44
|
-2.92 |
-2.96 |
|
KGETPPPP |
7.26
|
-3.14 |
-3.18 |
| P36006 |
PKDPKFEA |
5.05
|
-1.19 |
-1.23 |
|
NKKPKNPG |
5.43
|
-2.30 |
-2.34 |
|
ANIPIPPP |
6.31
|
-2.91 |
-2.95 |
| P38753 |
YPSNLPIQ |
5.99
|
-3.79 |
-3.83 |
|
SNLPIQHP |
6.13
|
-2.43 |
-2.47 |
|
NNTPVMPP |
6.16
|
-1.58 |
-1.62 |
| P38237 |
DPFVPPPN |
6.21
|
-2.45 |
-2.49 |
|
DLNDPFVP |
6.70
|
-1.88 |
-1.92 |
|
FQIPSKPE |
6.86
|
-0.46 |
-0.50 |
| P34245 |
GPWPGPAE |
7.05
|
-1.68 |
-1.72 |
|
AYSTPFGP |
7.51
|
-1.77 |
-1.81 |
|
PFGPWPGP |
7.54
|
-2.09 |
-2.13 |
| Q01389 |
RSKPLPPQ |
5.37
|
-3.29 |
-3.33 |
|
SQFPNLTP |
5.76
|
-1.73 |
-1.77 |
|
PQTPSYYY |
5.83
|
0.36 |
0.32 |
| Q03306 |
PPLPQMEF |
4.20
|
-4.68 |
-4.72 |
|
YRQPTPSP |
4.42
|
-3.10 |
-3.14 |
|
GRLPNSAP |
5.64
|
-2.23 |
-2.27 |
| P34758 |
QPQHLPPP |
3.93
|
-5.54 |
-5.58 |
|
QQLPLEPL |
4.50
|
-1.92 |
-1.96 |
|
VPQQLPLE |
4.90
|
-3.44 |
-3.48 |
| P53933 |
RRRPPPPP |
4.89
|
-3.52 |
-3.56 |
|
TRRRPPPP |
5.61
|
-3.10 |
-3.14 |
|
NDLPMELP |
6.09
|
-2.28 |
-2.32 |
| P32381 |
LTEPPMNP |
8.00
|
-2.03 |
-2.07 |
| Q00453 |
APIPLPHQ |
4.68
|
-3.72 |
-3.76 |
|
PYFPHPMP |
5.45
|
-2.36 |
-2.40 |
|
IPLPHQPP |
5.54
|
-2.61 |
-2.65 |
| P40021 |
PPLPPPLF |
4.55
|
-3.68 |
-3.72 |
|
PPLPPPAR |
4.65
|
-3.51 |
-3.55 |
|
VLNSPPLP |
6.34
|
-2.75 |
-2.79 |
| P36150 |
VVNPSSPS |
7.48
|
1.10 |
1.06 |
| Q04439 |
PKEPMFEA |
4.29
|
-3.38 |
-3.42 |
|
SKKPAPPP |
5.28
|
-3.05 |
-3.09 |
|
QANIPPPP |
6.13
|
-3.07 |
-3.11 |
| Q12446 |
QFAPLPDP |
4.77
|
-4.05 |
-4.09 |
|
VRLPAPPP |
5.00
|
-3.43 |
-3.47 |
|
HKAPPPPP |
5.30
|
-3.56 |
-3.60 |
| Q01560 |
PPEPQPYY |
5.14
|
-3.80 |
-3.84 |
|
EPQPYYPP |
5.18
|
-3.24 |
-3.28 |
|
QPYYPPPP |
5.96
|
-3.32 |
-3.36 |
| P00950 |
SFDVPPPP |
7.27
|
-2.39 |
-2.43 |
|
FDVPPPPI |
8.02
|
-1.21 |
-1.25 |
| P53735 |
PKLVPPPP |
5.02
|
-3.21 |
-3.25 |
|
KLVPPPPR |
5.57
|
-3.77 |
-3.81 |
|
APKLVPPP |
5.82
|
-3.79 |
-3.83 |
| P33334 |
SKMPTRFP |
4.59
|
-2.84 |
-2.88 |
|
GPKFEPLY |
5.67
|
-2.55 |
-2.59 |
|
LALPPPPP |
6.02
|
-3.84 |
-3.88 |
| P40523 |
TPLPTPVP |
5.39
|
-3.40 |
-3.44 |
|
NITPLPTP |
5.88
|
-2.44 |
-2.48 |
|
PPLAPPPH |
5.99
|
-2.37 |
-2.41 |
| P40563 |
RRAPPPVP |
6.36
|
-3.22 |
-3.26 |
|
NPGQLPPS |
6.64
|
-2.89 |
-2.93 |
|
PPVPKKPS |
7.15
|
-2.39 |
-2.43 |
| Q08989 |
PKGPPPPP |
6.00
|
-2.73 |
-2.77 |
|
HPKGPPPP |
6.45
|
-3.28 |
-3.32 |
|
NGDHPKGP |
8.23
|
-1.17 |
-1.21 |
| P37370 |
SQMPKPRP |
4.19
|
-4.14 |
-4.18 |
|
SKNPTKSP |
4.27
|
-1.60 |
-1.64 |
|
PLAPLPPP |
4.39
|
-4.93 |
-4.97 |
| P39743 |
YSNPLTSP |
6.66
|
-1.62 |
-1.66 |
|
NPLTSPVA |
7.33
|
-1.42 |
-1.46 |
| Q03900 |
LPNTPSGA |
7.63
|
-0.26 |
-0.30 |
|
