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Matrix information:
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ADAN-name: MYO5_1ZUY-7.PDB
Scoring matrix: MYO5_1ZUY-7_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.33
Foldx random average score for Saccharomyces cerevisiae: 9.087 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1339655
Proteins after disorder filtering: 4481
Total fragments: 58458
Proteins after pattern filtering: 2114
Total fragments: 11379
Proteins after MINT filtering: 44
Total fragments: 811 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAA |
11.33
|
2.54 |
0.00 |
| Best peptides |
KRPRWPWR |
0.00
|
-2.14 |
-4.68 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPGQPPLI |
5.29
|
-3.32 |
-5.86 |
|
LLPPLPGQ |
7.08
|
-1.83 |
-4.37 |
|
LPPLPGQP |
7.51
|
-4.42 |
-6.96 |
| P39113 |
RGPRRPQK |
5.55
|
-2.70 |
-5.24 |
|
APPPPPHK |
6.00
|
-2.60 |
-5.14 |
|
GPRRPQKN |
6.64
|
-2.88 |
-5.42 |
| P40073 |
PQQQPSHT |
8.35
|
-1.13 |
-3.67 |
|
YPQQQPSH |
8.44
|
-0.08 |
-2.62 |
| P25604 |
KPKSPHLK |
5.75
|
-2.40 |
-4.94 |
|
LPPPPPPQ |
5.81
|
-3.44 |
-5.98 |
|
KPPLPPPP |
6.32
|
-4.94 |
-7.48 |
| P25623 |
TPPLPPHA |
6.08
|
-1.74 |
-4.28 |
|
KPLPVEPA |
6.71
|
-0.82 |
-3.36 |
|
QPPLQPQS |
6.87
|
-1.77 |
-4.31 |
| Q05933 |
TPGFPLNN |
7.67
|
-1.05 |
-3.59 |
|
FRGPAYPS |
7.94
|
0.39 |
-2.15 |
|
LPGTPGFP |
8.16
|
-5.19 |
-7.73 |
| P53094 |
KLPPLPLT |
4.58
|
-2.78 |
-5.32 |
|
FPQSPIRA |
6.50
|
-1.26 |
-3.80 |
|
LPPLPLTS |
6.77
|
-3.35 |
-5.89 |
| Q12451 |
QPHLLPWL |
4.39
|
-3.21 |
-5.75 |
|
LLPWLPPT |
6.70
|
-1.93 |
-4.47 |
|
LPWLPPTD |
6.91
|
-2.55 |
-5.09 |
| P15891 |
QPPLPSRN |
4.44
|
-3.89 |
-6.43 |
|
APPPPPRR |
4.82
|
-3.80 |
-6.34 |
|
PPPPPRRA |
5.18
|
-2.82 |
-5.36 |
| P48562 |
KPPISAPR |
4.83
|
-2.34 |
-4.88 |
|
MRQAPKRP |
5.84
|
-4.02 |
-6.56 |
|
KQPQSPLS |
5.85
|
-1.19 |
-3.73 |
| P40341 |
PPPKPPLN |
5.44
|
-4.10 |
-6.64 |
|
PPPPPPPK |
6.49
|
-2.77 |
-5.31 |
|
KPPLNDPS |
6.95
|
-1.81 |
-4.35 |
| Q08912 |
PPPPPPDE |
6.88
|
-1.67 |
-4.21 |
|
PPPPPPPD |
6.89
|
-1.98 |
-4.52 |
|
PPPPPDEK |
7.18
|
-1.38 |
-3.92 |
| P17555 |
KSGPPPRP |
6.44
|
-4.10 |
-6.64 |
|
RPKKPSTL |
6.54
|
-2.67 |
-5.21 |
|
APPPPPPA |
6.54
|
-2.75 |
-5.29 |
| Q12342 |
KAPPPPPP |
7.58
|
-3.68 |
-6.22 |
|
TPSTPSDG |
8.29
|
0.50 |
-2.04 |
|
PPPPPPPP |
8.57
|
-3.49 |
-6.03 |
| P47068 |
TAPPLPRA |
6.77
|
-1.27 |
-3.81 |
|
PPHVPSLT |
6.79
|
-2.43 |
-4.97 |
|
APSPPPHQ |
6.82
|
-2.92 |
-5.46 |
| P38822 |
PEVPPPRR |
6.09
|
-2.97 |
-5.51 |
|
APEVPPPR |
6.89
|
-3.16 |
-5.70 |
| P04050 |
PPVRPSIS |
6.36
|
-2.73 |
-5.27 |
|
LPVPPPPV |
6.44
|
-3.20 |
-5.74 |
|
PVPPPPVR |
7.18
|
-2.35 |
-4.89 |
| P40450 |
PPPLPDLF |
6.32
|
-2.78 |
-5.32 |
|
SPKLFPRL |
6.54
|
-2.29 |
-4.83 |
|
KLPQLPPP |
6.74
|
-3.33 |
-5.87 |
| P40453 |
RPPPPPPV |
5.36
|
-2.70 |
-5.24 |
|
KPPDLPIR |
5.45
|
-1.99 |
-4.53 |
|
KRPPPPPP |
5.49
|
-3.98 |
-6.52 |
| Q12168 |
PPPLPPRA |
4.69
|
-3.68 |
-6.22 |
|
DPYFPQFR |
6.90
|
-2.70 |
-5.24 |
|
HPVPKPNI |
7.18
|
-0.56 |
-3.10 |
| P41832 |
PPPPPPMA |
5.53
|
-3.41 |
-5.95 |
|
PPPPMALF |
6.37
|
-2.10 |
-4.64 |
|
PPPPPPPM |
6.71
|
-2.35 |
-4.89 |
| P36006 |
PPPPPPMG |
5.79
|
-3.41 |
-5.95 |
|
KKPKNPGG |
6.95
|
-1.81 |
-4.35 |
|
KPKNPGGL |
7.24
|
-1.89 |
-4.43 |
| P38753 |
TPVMPPQR |
6.56
|
-2.41 |
-4.95 |
|
PVMPPQRQ |
7.11
|
-2.72 |
-5.26 |
|
YPSNLPIQ |
7.33
|
-2.19 |
-4.73 |
| P38237 |
PPNVPKKD |
7.23
|
-1.93 |
-4.47 |
|
PPPNVPKK |
7.88
|
-0.97 |
-3.51 |
|
DPFVPPPN |
7.90
|
-1.99 |
-4.53 |
| P34245 |
FGPWPGPA |
7.50
|
-0.83 |
-3.37 |
|
YSTPFGPW |
8.58
|
-0.62 |
-3.16 |
| Q01389 |
KPLPPQLL |
5.00
|
-2.71 |
-5.25 |
|
KRSKPLPP |
5.89
|
-3.78 |
-6.32 |
|
SRPVPPDS |
6.36
|
-1.85 |
-4.39 |
| Q03306 |
KPNVPPLQ |
4.57
|
-3.50 |
-6.04 |
|
KPFRIPSS |
5.24
|
-1.99 |
-4.53 |
|
PPKVPVIN |
6.97
|
-3.03 |
-5.57 |
| P34758 |
PPPPPPRA |
4.86
|
-3.23 |
-5.77 |
|
LPPPPPPR |
5.20
|
-3.65 |
-6.19 |
|
QPNKPNYG |
5.78
|
-3.33 |
-5.87 |
| P53933 |
RRPPPPPI |
4.36
|
-2.59 |
-5.13 |
|
PPPLPNRQ |
5.79
|
-3.04 |
-5.58 |
|
RRRPPPPP |
6.25
|
-3.93 |
-6.47 |
| P32381 |
TEPPMNPL |
8.65
|
0.01 |
-2.53 |
| Q00453 |
QPPPLPIY |
5.70
|
-2.09 |
-4.63 |
|
LPHQPPPL |
5.74
|
-2.67 |
-5.21 |
|
FPHPMPSA |
6.46
|
-1.10 |
-3.64 |
| P40021 |
PLPPPARS |
5.90
|
-2.86 |
-5.40 |
|
PPLPPPLF |
6.46
|
-2.34 |
-4.88 |
|
LPSTPSQM |
6.68
|
-0.84 |
-3.38 |
| Q04439 |
KPAPPPPG |
5.10
|
-3.23 |
-5.77 |
|
KPKEPMFE |
5.45
|
-3.18 |
-5.72 |
|
RPSPPTAA |
6.57
|
-1.65 |
-4.19 |
| Q12446 |
APPPPPRR |
4.82
|
-3.80 |
-6.34 |
|
APPPPPRA |
4.94
|
-3.45 |
-5.99 |
|
LPQLPNRN |
5.00
|
-2.68 |
-5.22 |
| Q01560 |
QPPEPQPY |
6.97
|
-1.47 |
-4.01 |
|
YPPPPPGE |
7.21
|
-1.34 |
-3.88 |
|
YYPPPPPG |
7.22
|
-2.20 |
-4.74 |
| P00950 |
FDVPPPPI |
7.75
|
-1.54 |
-4.08 |
|
DVPPPPID |
7.84
|
-0.90 |
-3.44 |
|
VPPPPIDA |
7.88
|
-1.58 |
-4.12 |
| P53735 |
KLVPPPPR |
4.99
|
-3.38 |
-5.92 |
|
LVPPPPRT |
5.08
|
-3.43 |
-5.97 |
|
PPPPRTRS |
6.98
|
-1.49 |
-4.03 |
| P33334 |
MPTRFPPA |
4.55
|
-4.01 |
-6.55 |
|
LPPPPPGF |
6.39
|
-2.62 |
-5.16 |
|
PPPPPGLD |
6.53
|
-2.37 |
-4.91 |
| P40523 |
PLAPPPHG |
6.71
|
-2.58 |
-5.12 |
|
PVGVPPLA |
7.15
|
-2.33 |
-4.87 |
|
PPLAPPPH |
7.97
|
-1.96 |
-4.50 |
| P40563 |
PSERPKRR |
5.62
|
-3.01 |
-5.55 |
|
RRAPPPVP |
6.40
|
-3.75 |
-6.29 |
|
RAPPPVPK |
6.59
|
-1.75 |
-4.29 |
| Q08989 |
PPPPPPDE |
6.88
|
-1.67 |
-4.21 |
|
PPPPPPPD |
6.89
|
-1.98 |
-4.52 |
|
PPPPPDEK |
7.18
|
-1.38 |
-3.92 |
| P37370 |
RPHMPSVR |
4.89
|
-3.73 |
-6.27 |
|
MPKPRPFQ |
5.23
|
-4.55 |
-7.09 |
|
QMPKPRPF |
5.27
|
-2.99 |
-5.53 |
| P39743 |
NPLTSPVA |
8.71
|
0.49 |
-2.05 |
| Q03900 |
LPNTPSGA |
7.57
|
-1.01 |
-3.55 |
|
PSGAPKLK |
8.37
|
-1.66 |
-4.20 |
|
