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Matrix information:
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ADAN-name: MYO5_1ZUY-6.PDB
Scoring matrix: MYO5_1ZUY-6_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.12
Foldx random average score for Saccharomyces cerevisiae: 18.185 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3200363
Proteins after random average filtering: 7179
Total fragments: 1954480
Proteins after disorder filtering: 4632
Total fragments: 122460
Proteins after pattern filtering: 2311
Total fragments: 21333
Proteins after MINT filtering: 44
Total fragments: 1459 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
15.12
|
2.95 |
0.00 |
| Best peptides |
HLRMGWRRPY |
0.00
|
-2.59 |
-5.54 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PPLPGQPPLI |
13.52
|
-1.24 |
-4.19 |
|
PLLPPLPGQP |
14.57
|
0.81 |
-2.14 |
|
PGQPPLINIG |
15.12
|
-0.17 |
-3.12 |
| P39113 |
ASHRGPRRPQ |
5.96
|
-2.57 |
-5.52 |
|
MSPLGAPPPP |
10.24
|
-1.59 |
-4.54 |
|
THPEGPNCTN |
12.04
|
-1.19 |
-4.14 |
| P40073 |
FDGYPQQQPS |
15.03
|
1.02 |
-1.93 |
|
DGYPQQQPSH |
16.94
|
2.91 |
-0.04 |
|
GYPQQQPSHT |
17.71
|
3.21 |
0.26 |
| P25604 |
HLKPPLPPPP |
10.81
|
-0.87 |
-3.82 |
|
QDQAPSLPPK |
13.28
|
0.44 |
-2.51 |
|
PQDQAPSLPP |
13.42
|
1.49 |
-1.46 |
| P25623 |
TFTPSEVPPS |
13.55
|
0.35 |
-2.60 |
|
ISQPPLQPQS |
13.60
|
0.56 |
-2.39 |
|
PVEPASPSIS |
13.83
|
-0.32 |
-3.27 |
| Q05933 |
TKFRGPAYPS |
10.06
|
-2.65 |
-5.60 |
|
FTLPGTPGFP |
12.10
|
-0.63 |
-3.58 |
|
FRGPAYPSNS |
12.18
|
-1.07 |
-4.02 |
| P53094 |
AFPQSPIRAY |
11.18
|
1.05 |
-1.90 |
|
ADAKAPNTPS |
12.46
|
0.43 |
-2.52 |
|
PLKLPPLPLT |
12.61
|
-0.69 |
-3.64 |
| Q12451 |
PHLLPWLPPT |
13.72
|
0.77 |
-2.18 |
|
HAPPPVPNET |
13.79
|
0.95 |
-2.00 |
|
KHAPPPVPNE |
14.30
|
-0.47 |
-3.42 |
| P15891 |
DEPEGEPDVK |
12.01
|
-1.63 |
-4.58 |
|
RSSAAPPPPP |
12.05
|
-0.46 |
-3.41 |
|
APPPPPRRAT |
12.23
|
0.08 |
-2.87 |
| P48562 |
QFPRGPMHPN |
7.26
|
-4.93 |
-7.88 |
|
NIGPAPRPPS |
9.06
|
-2.36 |
-5.31 |
|
TMRQAPKRPD |
9.08
|
-0.55 |
-3.50 |
| P40341 |
RNIPPPPPPP |
12.99
|
-1.46 |
-4.41 |
|
SRNIPPPPPP |
13.70
|
-1.03 |
-3.98 |
|
PLNDPSNPVS |
14.09
|
1.06 |
-1.89 |
| Q08912 |
DHPKGPPPPP |
11.77
|
-1.99 |
-4.94 |
|
TPSWGPSPMG |
12.82
|
-0.01 |
-2.96 |
|
PKGPPPPPPP |
14.15
|
-0.05 |
-3.00 |
| P17555 |
KSGPPPRPKK |
10.70
|
-1.20 |
-4.15 |
|
TAAPAPPPPP |
12.68
|
-0.56 |
-3.51 |
|
GSKSGPPPRP |
12.98
|
-1.93 |
-4.88 |
| Q12342 |
RKAKAPPPPP |
10.16
|
-1.80 |
-4.75 |
|
KAPPPPPPPP |
13.68
|
-1.20 |
-4.15 |
|
AKAPPPPPPP |
13.99
|
-0.21 |
-3.16 |
| P47068 |
HSHTAPSPPP |
10.47
|
0.78 |
-2.17 |
|
YVPPGIPTND |
10.86
|
-2.54 |
-5.49 |
|
YYVPPGIPTN |
10.97
|
-1.25 |
-4.20 |
| P38822 |
DRGPAPEVPP |
13.19
|
1.07 |
-1.88 |
|
RGPAPEVPPP |
14.50
|
-0.74 |
-3.69 |
|
APEVPPPRRS |
15.34
|
0.78 |
-2.17 |
| P04050 |
VSSPGFSPTS |
11.10
|
-0.99 |
-3.94 |
|
GYSPGSPAYS |
11.11
|
-1.19 |
-4.14 |
|
PTSPGYSPGS |
11.88
|
-1.31 |
-4.26 |
| P40450 |
IAAPAPPPLP |
11.87
|
-0.42 |
-3.37 |
|
QLPPPPPPPP |
12.80
|
-0.86 |
-3.81 |
|
SCIAAPAPPP |
13.15
|
0.94 |
-2.01 |
| P40453 |
RKRPPPPPPV |
11.51
|
-2.18 |
-5.13 |
|
SWKPPDLPIR |
12.08
|
-0.80 |
-3.75 |
|
RLRKRPPPPP |
12.13
|
1.25 |
-1.70 |
| Q12168 |
PNRPGGTTNR |
10.92
|
-1.91 |
-4.86 |
|
NRGPPPLPPR |
11.25
|
-0.46 |
-3.41 |
|
TTNRGPPPLP |
11.67
|
-2.44 |
-5.39 |
| P41832 |
GDSPAPPPPP |
12.76
|
-0.66 |
-3.61 |
|
VIPPAPPMMP |
13.35
|
-0.69 |
-3.64 |
|
LSSQPPPPPP |
14.43
|
-0.08 |
-3.03 |
| P36006 |
PKNPGGLSGK |
9.16
|
-2.75 |
-5.70 |
|
PPPMGQPKDP |
13.72
|
-1.92 |
-4.87 |
|
NIPIPPPPPP |
13.94
|
-1.11 |
-4.06 |
| P38753 |
PVMPPQRQSY |
12.03
|
-0.57 |
-3.52 |
|
YSPYPSNLPI |
13.19
|
0.44 |
-2.51 |
|
PPVPGPALYA |
13.45
|
-0.84 |
-3.79 |
| P38237 |
NFQIPSKPEN |
11.48
|
-0.23 |
-3.18 |
|
PFVPPPNVPK |
11.97
|
0.21 |
-2.74 |
|
FVPPPNVPKK |
13.81
|
-1.29 |
-4.24 |
| P34245 |
STPFGPWPGP |
11.48
|
-0.52 |
-3.47 |
|
GPWPGPAECL |
13.73
|
-0.23 |
-3.18 |
|
AYSTPFGPWP |
15.57
|
1.43 |
-1.52 |
| Q01389 |
PKREAPKPPA |
10.31
|
-1.22 |
-4.17 |
|
IGEEAPTKPN |
11.94
|
0.14 |
-2.81 |
|
PKPPANTSPQ |
12.40
|
-0.33 |
-3.28 |
| Q03306 |
GEEKPFRIPS |
11.89
|
0.17 |
-2.78 |
|
NKSIPRTKPN |
12.77
|
-0.13 |
-3.08 |
|
PFRIPSSTKD |
13.66
|
0.35 |
-2.60 |
| P34758 |
HLPPPPPPRA |
11.61
|
-1.69 |
-4.64 |
|
QLPLEPLKPT |
12.87
|
2.40 |
-0.55 |
|
QHLPPPPPPR |
13.04
|
-0.40 |
-3.35 |
| P53933 |
RVAPPPLPNR |
11.44
|
-2.22 |
-5.17 |
|
VSYPGNPTSR |
11.47
|
-1.31 |
-4.26 |
|
AKRVAPPPLP |
11.82
|
-1.10 |
-4.05 |
| P32381 |
LLTEPPMNPL |
10.94
|
-1.93 |
-4.88 |
|
ILLTEPPMNP |
14.56
|
2.37 |
-0.58 |
| Q00453 |
LYAPPYFPHP |
12.38
|
-0.72 |
-3.67 |
|
ISTPASPQDT |
12.39
|
1.13 |
-1.82 |
|
PMPSAPIPLP |
12.59
|
-0.75 |
-3.70 |
| P40021 |
TKNTGPPPPL |
10.56
|
-2.83 |
-5.78 |
|
PLPPPARSQS |
11.95
|
-1.04 |
-3.99 |
|
NYVISPNLPT |
12.38
|
0.73 |
-2.22 |
| Q04439 |
SKKPAPPPPG |
11.63
|
-0.70 |
-3.65 |
|
HSKKPAPPPP |
12.85
|
0.48 |
-2.47 |
|
IPTPPQNRDV |
12.99
|
2.60 |
-0.35 |
| Q12446 |
RRGPAPPPPP |
10.48
|
-1.21 |
-4.16 |
|
TGRRGPAPPP |
10.68
|
-2.27 |
-5.22 |
|
TKHKAPPPPP |
11.25
|
-1.09 |
-4.04 |
| Q01560 |
HHQPPEPQPY |
12.18
|
-0.14 |
-3.09 |
|
HQPPEPQPYY |
12.19
|
3.47 |
0.52 |
|
QEPPAPQEQN |
12.33
|
-0.42 |
-3.37 |
| P00950 |
SFDVPPPPID |
14.34
|
0.53 |
-2.42 |
|
DVPPPPIDAS |
14.43
|
-1.34 |
-4.29 |
|
FDVPPPPIDA |
14.62
|
-0.65 |
-3.60 |
| P53735 |
KLVPPPPRTR |
9.68
|
-2.26 |
-5.21 |
|
LVPPPPRTRS |
11.48
|
-2.50 |
-5.45 |
|
PKLVPPPPRT |
14.40
|
-0.90 |
-3.85 |
| P33334 |
NAIPGGPKFE |
11.27
|
-1.23 |
-4.18 |
|
FFDPSLNPIP |
12.11
|
0.70 |
-2.25 |
|
AIPGGPKFEP |
12.20
|
-1.50 |
-4.45 |
| P40523 |
YMHNSPRNPD |
11.57
|
-1.25 |
-4.20 |
|
GAPPGTVPNM |
11.60
|
-2.08 |
-5.03 |
|
PVPVGVPPLA |
12.77
|
-2.55 |
-5.50 |
| P40563 |
MVNPGQLPPS |
8.32
|
-3.94 |
-6.89 |
|
PSERPKRRAP |
10.68
|
0.20 |
-2.75 |
|
PKRRAPPPVP |
11.58
|
-0.96 |
-3.91 |
| Q08989 |
DHPKGPPPPP |
11.77
|
-1.99 |
-4.94 |
|
PKGPPPPPPP |
14.15
|
-0.05 |
-3.00 |
|
KGPPPPPPPP |
14.31
|
-1.15 |
-4.10 |
| P37370 |
PALPGHVPPP |
10.61
|
-2.33 |
-5.28 |
|
SIPLAPLPPP |
11.59
|
-2.01 |
-4.96 |
|
PLSPAPAVPS |
11.95
|
0.17 |
-2.78 |
| P39743 |
AYSNPLTSPV |
15.31
|
1.22 |
-1.73 |
|
YSNPLTSPVA |
16.70
|
3.96 |
1.01 |
| Q03900 |
NTPSGAPKLK |
13.44
|
-0.94 |
-3.89 |
|
PSGAPKLKNY |
14.95
|
1.08 |
-1.87 |
|
TPSGAPKLKN |
15.23
|
1.70 |
-1.25 |
|
