ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1ZUY-27.PDB
Scoring matrix: MYO5_1ZUY-27_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 10.29
Foldx random average score for Saccharomyces cerevisiae: 12.077

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1851572
Proteins after disorder filtering: 4730
 Total fragments: 146894
Proteins after pattern filtering: 2285
 Total fragments: 17949
Proteins after MINT filtering: 45
 Total fragments: 1140

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

10.29

-4.39

0.00
Best peptides

RGWRWPPRR

0.00

-5.63

-1.24
         
Interactors      
P53145

LPGQPPLIN

9.48

-6.66

-2.27

PLPGQPPLI

10.27

-3.69

0.70

PNEPLLPPL

10.56

-5.19

-0.80
P39113

RGPRRPQKN

3.94

-6.09

-1.70

LFTHPEGPN

6.13

-6.00

-1.61

ASHRGPRRP

6.59

-5.03

-0.64
P40073

FDGYPQQQP

9.51

-6.10

-1.71

YPQQQPSHT

11.22

-4.65

-0.26
P25604

KSPHLKPPL

5.17

-6.24

-1.85

LPPKPKSPH

7.28

-5.39

-1.00

QDQAPSLPP

7.96

-6.40

-2.01
P25623

LPVEPASPS

5.59

-6.30

-1.91

FTPSEVPPS

6.77

-6.03

-1.64

LPPHATPKN

6.81

-4.70

-0.31
Q05933

RGPAYPSNS

5.97

-4.81

-0.42

KFRGPAYPS

6.67

-5.46

-1.07

TKFRGPAYP

7.88

-2.65

1.74
P53094

REPNEPPPP

5.52

-6.48

-2.09

EPNEPPPPC

6.10

-6.30

-1.91

QTREPNEPP

6.59

-5.64

-1.25
Q12451

APKHAPPPV

7.05

-5.48

-1.09

PKHAPPPVP

8.28

-6.31

-1.92

AAPKHAPPP

8.87

-5.15

-0.76
P15891

RSSAAPPPP

4.91

-7.07

-2.68

SSAAPPPPP

5.65

-7.27

-2.88

FTPSKSPAP

7.31

-5.92

-1.53
P48562

IGPAPRPPS

4.69

-7.92

-3.53

MRQAPKRPD

5.25

-7.71

-3.32

QNIGPAPRP

5.95

-6.23

-1.84
P40341

RNIPPPPPP

6.27

-7.71

-3.32

NSRNIPPPP

6.76

-6.44

-2.05

IPPPPPPPP

7.97

-8.07

-3.68
Q08912

HPKGPPPPP

6.50

-6.46

-2.07

HGDHPKGPP

6.84

-5.60

-1.21

KGPPPPPPP

6.96

-7.71

-3.32
P17555

PPPRPKKPS

5.93

-6.95

-2.56

SKSGPPPRP

6.01

-6.46

-2.07

AAPAPPPPP

6.05

-7.43

-3.04
Q12342

KAKAPPPPP

4.46

-7.50

-3.11

RKAKAPPPP

6.75

-6.07

-1.68

KAPPPPPPP

7.65

-7.73

-3.34
P47068

TPPAPPAPP

5.90

-6.71

-2.32

LPRAPPVPP

6.09

-6.99

-2.60

PSSNPFFRK

6.37

-5.27

-0.88
P38822

RGPAPEVPP

4.99

-6.89

-2.50

PAPEVPPPR

7.06

-5.65

-1.26

APEVPPPRR

9.81

-6.01

-1.62
P04050

YGEAPTSPG

6.05

-6.35

-1.96

GSPAYSPKQ

8.20

-4.97

-0.58

PGYSPGSPA

8.28

-5.67

-1.28
P40450

CIAAPAPPP

6.58

-6.34

-1.95

TPPAPPLPN

7.08

-6.74

-2.35

AAPAPPPLP

7.20

-6.33

-1.94
P40453

LRKRPPPPP

2.82

-7.00

-2.61

KVPEPPSWK

4.89

-5.05

-0.66

RLRKRPPPP

5.64

-6.93

-2.54
Q12168

RGPPPLPPR

6.14

-7.41

-3.02

KVQHPVPKP

6.27

-5.29

-0.90

TNRGPPPLP

7.37

-5.37

-0.98
P41832

DSPAPPPPP

5.96

-7.39

-3.00

LSSQPPPPP

6.55

-7.88

-3.49

TGDSPAPPP

6.56

-5.97

-1.58
P36006

KPKNPGGLS

7.65

-5.46

-1.07

SNKKPKNPG

7.93

-5.44

-1.05

IPIPPPPPP

8.10

-7.52

-3.13
P38753

TPVMPPQRQ

6.68

-7.21

-2.82

PYPSNLPIQ

8.65

-4.69

-0.30

AHISPPVPG

9.22

-5.25

-0.86
P38237

LNDPFVPPP

8.54

-5.82

-1.43

QIPSKPENT

8.62

-4.71

-0.32

PPPNVPKKD

9.31

-5.48

-1.09
P34245

YSTPFGPWP

8.87

-4.43

-0.04

TPFGPWPGP

8.99

-3.86

0.53

STPFGPWPG

10.12

-5.21

-0.82
Q01389

KREAPKPPA

3.98

-7.65

-3.26

TPSRPVPPD

5.44

-5.28

-0.89

KRSKPLPPQ

6.16

-6.58

-2.19
Q03306

ASSEPSSPP

7.08

-5.65

-1.26

KPFRIPSST

7.32

-3.06

1.33

RLPNSAPST

7.98

-4.43

-0.04
P34758

LPLEPLKPT

4.28

-6.56

-2.17

LPPPPPPRA

6.45

-9.02

-4.63

LSSSPSPNP

6.46

-5.55

-1.16
P53933

RTRRRPPPP

3.13

-6.51

-2.12

TRRRPPPPP

4.09

-6.85

-2.46

KRVAPPPLP

5.17

-7.11

-2.72
P32381

LLTEPPMNP

7.55

-5.40

-1.01

LTEPPMNPL

8.96

-6.06

-1.67
Q00453

MPSAPIPLP

6.00

-7.08

-2.69

SLYAPPYFP

6.63

-5.68

-1.29

YFPHPMPSA

6.91

-5.67

-1.28
P40021

KNTGPPPPL

5.36

-6.62

-2.23

LNSPPLPPP

7.75

-7.30

-2.91

SESHPPNHP

7.92

-4.03

0.36
P36150

IVVNPSSPS

7.58

-6.04

-1.65
Q04439

KKPAPPPPG

4.10

-8.50

-4.11

SNARPSPPT

5.00

-6.95

-2.56

KPKEPMFEA

5.09

-5.35

-0.96
Q12446

RGPAPPPPP

2.67

-8.40

-4.01

RNNRPVPPP

3.09

-6.56

-2.17

RLPAPPPPP

3.36

-8.21

-3.82
Q01560

QPPEPQPYY

6.18

-5.62

-1.23

APQEPPAPQ

6.43

-6.21

-1.82

PPQAPDAPQ

7.31

-6.97

-2.58
P00950

RSFDVPPPP

5.97

-5.84

-1.45

FDVPPPPID

8.15

-7.06

-2.67

SFDVPPPPI

11.41

-5.32

-0.93
P53735

KLVPPPPRT

7.32

-7.29

-2.90

PAPKLVPPP

9.81

-5.24

-0.85

VPPPPRTRS

10.74

-5.22

-0.83
P33334

MPTRFPPAV

5.73

-5.93

-1.54

SDLALPPPP

6.51

-6.26

-1.87

FDPSLNPIP

6.77

-6.15

-1.76
P40523

MHNSPRNPD

6.76

-6.10

-1.71

PPLAPPPHG

7.14

-5.88

-1.49

YMHNSPRNP

8.67

-4.12

0.27
P40563

PSERPKRRA

5.04

-7.37

-2.98

KRRAPPPVP

5.75

-6.92

-2.53

ANSEPPTPA

7.31

-4.92

-0.53
Q08989

HPKGPPPPP

6.50

-6.46

-2.07

KGPPPPPPP

6.96

-7.71

-3.32

NGDHPKGPP

7.20

-5.64

-1.25
P37370

IPLAPLPPP

5.04

-8.07

-3.68

SMPAPPPPP

5.56

-7.43

-3.04

SAPAPPPPP

5.60

-7.27

-2.88
P39743

AYSNPLTSP

11.09

-3.78

0.61

YSNPLTSPV

11.65

-4.53

-0.14
Q03900

PSGAPKLKN

9.69

-5.69

-1.30

TPSGAPKLK

9.91

-3.24

1.15

NTPSGAPKL

10.31

-3.68

0.71

 


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