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Matrix information:
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ADAN-name: MYO5_1ZUY-26.PDB
Scoring matrix: MYO5_1ZUY-26_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.66
Foldx random average score for Saccharomyces cerevisiae: 13.381 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1310621
Proteins after disorder filtering: 4317
Total fragments: 61602
Proteins after pattern filtering: 2122
Total fragments: 11905
Proteins after MINT filtering: 43
Total fragments: 820 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
16.66
|
-1.05 |
0.00 |
| Best peptides |
DDRKRRPPR |
0.00
|
-6.41 |
-5.36 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
NEPLLPPLP |
10.61
|
-5.45 |
-4.40 |
|
EPLLPPLPG |
11.16
|
-4.68 |
-3.63 |
|
PLPGQPPLI |
12.95
|
-3.89 |
-2.84 |
| P39113 |
GPRRPQKNR |
6.44
|
-3.99 |
-2.94 |
|
SHRGPRRPQ |
9.29
|
-5.69 |
-4.64 |
|
HRGPRRPQK |
9.81
|
-1.69 |
-0.64 |
| P40073 |
GYPQQQPSH |
10.84
|
-5.08 |
-4.03 |
| P25604 |
TPPLPPKPK |
8.76
|
-3.83 |
-2.78 |
|
KSPHLKPPL |
8.82
|
-4.65 |
-3.60 |
|
LPPKPKSPH |
9.01
|
-4.56 |
-3.51 |
| P25623 |
NLPKTVPIS |
10.11
|
-5.08 |
-4.03 |
|
QPPLQPQSK |
10.85
|
-4.38 |
-3.33 |
|
TKPLPVEPA |
10.88
|
-4.41 |
-3.36 |
| Q05933 |
FPVDPNTDR |
11.41
|
-2.50 |
-1.45 |
|
KFRGPAYPS |
12.00
|
-2.47 |
-1.42 |
|
HSTFPVDPN |
12.51
|
-2.41 |
-1.36 |
| P53094 |
NVPLPPQTR |
8.06
|
-3.98 |
-2.93 |
|
DDEDPVSPK |
9.93
|
-3.24 |
-2.19 |
|
SAFPQSPIR |
10.35
|
-1.05 |
-0.00 |
| Q12451 |
AAPKHAPPP |
10.39
|
-4.86 |
-3.81 |
|
APKHAPPPV |
11.16
|
-2.80 |
-1.75 |
|
LLPWLPPTD |
12.09
|
-4.21 |
-3.16 |
| P15891 |
SAAPPPPPR |
8.54
|
-2.03 |
-0.98 |
|
AAPPPPPRR |
8.57
|
-3.14 |
-2.09 |
|
AAQPPLPSR |
9.86
|
-3.09 |
-2.04 |
| P48562 |
IGPAPRPPS |
9.41
|
-4.84 |
-3.79 |
|
THVQPVAPK |
9.60
|
-3.57 |
-2.52 |
|
NGQFPRGPM |
9.62
|
-3.45 |
-2.40 |
| P40341 |
NSRNIPPPP |
9.31
|
-6.16 |
-5.11 |
|
PPPPPPPPK |
10.37
|
-3.63 |
-2.58 |
|
SRNIPPPPP |
10.75
|
-3.70 |
-2.65 |
| Q08912 |
DHPKGPPPP |
8.54
|
-5.68 |
-4.63 |
|
PPPPDEKDR |
10.27
|
-2.26 |
-1.21 |
|
HPKGPPPPP |
11.23
|
-4.18 |
-3.13 |
| P17555 |
SGPPPRPKK |
8.11
|
-3.17 |
-2.12 |
|
PPPRPKKPS |
10.53
|
-5.35 |
-4.30 |
|
PRPKKPSTL |
10.86
|
-4.34 |
-3.29 |
| Q12342 |
RKAKAPPPP |
10.40
|
-4.25 |
-3.20 |
|
KAKAPPPPP |
11.20
|
-4.53 |
-3.48 |
|
KAPPPPPPP |
11.92
|
-3.61 |
-2.56 |
| P47068 |
DPSSNPFFR |
8.50
|
-3.64 |
-2.59 |
|
PNTAPPLPR |
9.57
|
-2.14 |
-1.09 |
|
VPPHPVPSA |
9.99
|
-4.64 |
-3.59 |
| P38822 |
PAPEVPPPR |
7.18
|
-5.09 |
-4.04 |
|
APEVPPPRR |
8.48
|
-3.10 |
-2.05 |
|
DTPTTTPGS |
12.96
|
-4.83 |
-3.78 |
| P04050 |
LPVPPPPVR |
8.72
|
-1.54 |
-0.49 |
|
PPPPVRPSI |
10.81
|
-3.45 |
-2.40 |
|
CLPVPPPPV |
12.09
|
-4.43 |
-3.38 |
| P40450 |
SSSPKLFPR |
9.36
|
-2.13 |
-1.08 |
|
SSPKLFPRL |
9.44
|
-3.78 |
-2.73 |
|
PKLFPRLSS |
9.76
|
-4.63 |
-3.58 |
| P40453 |
RLRKRPPPP |
7.69
|
-5.24 |
-4.19 |
|
LRKRPPPPP |
9.35
|
-4.51 |
-3.46 |
|
PDLPIRLRK |
9.41
|
-2.54 |
-1.49 |
| Q12168 |
DDPYFPQFR |
6.82
|
-4.46 |
-3.41 |
|
RGPPPLPPR |
8.23
|
-4.17 |
-3.12 |
|
DPYFPQFRS |
10.33
|
-4.57 |
-3.52 |
| P41832 |
DSPAPPPPP |
9.94
|
-5.78 |
-4.73 |
|
PPPPPVPAK |
10.46
|
-3.55 |
-2.50 |
|
DGVIPPAPP |
11.44
|
-2.84 |
-1.79 |
| P36006 |
SNKKPKNPG |
10.02
|
-4.84 |
-3.79 |
|
NIPIPPPPP |
10.22
|
-5.55 |
-4.50 |
|
TANIPIPPP |
11.30
|
-4.67 |
-3.62 |
| P38753 |
NTPVMPPQR |
7.63
|
-4.92 |
-3.87 |
|
NLPIQHPTN |
11.95
|
-5.17 |
-4.12 |
|
TPVMPPQRQ |
11.96
|
-2.90 |
-1.85 |
| P38237 |
NDPFVPPPN |
9.90
|
-5.32 |
-4.27 |
|
VPPPNVPKK |
10.85
|
-3.29 |
-2.24 |
|
PDLNDPFVP |
11.68
|
-3.44 |
-2.39 |
| P34245 |
STPFGPWPG |
11.15
|
-4.59 |
-3.54 |
|
TPFGPWPGP |
12.74
|
-2.97 |
-1.92 |
| Q01389 |
PSYPSIFRR |
9.49
|
-2.84 |
-1.79 |
|
SGRRYPQTP |
10.31
|
-3.32 |
-2.27 |
|
RYPQTPSYY |
10.77
|
-3.55 |
-2.50 |
| Q03306 |
SPPLPQMEF |
9.59
|
-4.07 |
-3.02 |
|
SIPRTKPNV |
9.97
|
-5.34 |
-4.29 |
|
EKPFRIPSS |
10.20
|
-6.88 |
-5.83 |
| P34758 |
HLPPPPPPR |
7.36
|
-2.82 |
-1.77 |
|
HSQPNKPNY |
10.57
|
-2.77 |
-1.72 |
|
QPQHLPPPP |
10.85
|
-3.87 |
-2.82 |
| P53933 |
TRRRPPPPP |
7.58
|
-5.12 |
-4.07 |
|
RTRRRPPPP |
8.21
|
-5.75 |
-4.70 |
|
VAPPPLPNR |
9.45
|
-3.26 |
-2.21 |
| Q00453 |
YFPHPMPSA |
9.27
|
-5.21 |
-4.16 |
|
PLPHQPPPL |
10.05
|
-4.09 |
-3.04 |
|
APPYFPHPM |
10.89
|
-4.81 |
-3.76 |
| P40021 |
SPPLPPPAR |
5.89
|
-4.30 |
-3.25 |
|
PPPLPPPLF |
9.68
|
-5.28 |
-4.23 |
|
HPPNHPHSQ |
11.66
|
-4.52 |
-3.47 |
| Q04439 |
HSKKPAPPP |
9.59
|
-4.53 |
-3.48 |
|
NIPTPPQNR |
9.59
|
-3.83 |
-2.78 |
|
KPKEPMFEA |
9.75
|
-5.09 |
-4.04 |
| Q12446 |
PPPPPRASR |
8.16
|
-2.03 |
-0.98 |
|
PAPPPPPRR |
8.49
|
-2.85 |
-1.80 |
|
PAPPPPPHR |
8.74
|
-3.06 |
-2.01 |
| Q01560 |
QPPEPQPYY |
9.89
|
-5.35 |
-4.30 |
|
SAPQEPPAP |
10.93
|
-3.59 |
-2.54 |
|
PQPYYPPPP |
11.07
|
-5.33 |
-4.28 |
| P00950 |
RSFDVPPPP |
11.69
|
-3.21 |
-2.16 |
|
SFDVPPPPI |
12.10
|
-3.09 |
-2.04 |
| P53735 |
PKLVPPPPR |
7.19
|
-4.63 |
-3.58 |
|
PAPKLVPPP |
9.38
|
-5.63 |
-4.58 |
|
LVPPPPRTR |
9.91
|
-2.99 |
-1.94 |
| P33334 |
GGPKFEPLY |
8.77
|
-4.44 |
-3.39 |
|
SKMPTRFPP |
9.16
|
-2.61 |
-1.56 |
|
DTFLPPPPP |
9.82
|
-5.54 |
-4.49 |
| P40523 |
VPPLAPPPH |
9.79
|
-5.42 |
-4.37 |
|
PVPVGVPPL |
11.27
|
-4.76 |
-3.71 |
|
PPPHGPFST |
11.37
|
-3.06 |
-2.01 |
| P40563 |
EVTPKVPER |
8.87
|
-2.47 |
-1.42 |
|
AGTPNVPTR |
10.00
|
-1.64 |
-0.59 |
|
KRRAPPPVP |
10.17
|
-5.10 |
-4.05 |
| Q08989 |
DHPKGPPPP |
8.54
|
-5.68 |
-4.63 |
|
PPPPDEKGR |
10.02
|
-2.40 |
-1.35 |
|
HPKGPPPPP |
11.23
|
-4.18 |
-3.13 |
| P37370 |
SAPKVPQNR |
7.09
|
-2.59 |
-1.54 |
|
NRPHMPSVR |
7.27
|
-3.02 |
-1.97 |
|
KVPQNRPHM |
8.27
|
-4.93 |
-3.88 |
| P39743 |
SNPLTSPVA |
11.95
|
-3.47 |
-2.42 |
| Q03900 |
HLPNTPSGA |
12.34
|
-2.87 |
-1.82 |
|
TPSGAPKLK |
12.95
|
-1.24 |
-0.19 |
|
NTPSGAPKL |
12.96
|
-3.68 |
-2.63 |
|
