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Matrix information:
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ADAN-name: MYO5_1ZUY-20.PDB
Scoring matrix: MYO5_1ZUY-20_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.57
Foldx random average score for Saccharomyces cerevisiae: 17.773 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1356790
Proteins after disorder filtering: 4499
Total fragments: 65670
Proteins after pattern filtering: 1968
Total fragments: 6772
Proteins after MINT filtering: 41
Total fragments: 305 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
18.57
|
-0.68 |
0.00 |
| Best peptides |
RMFMRGRHF |
0.00
|
-8.36 |
-7.68 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPPLPGQPP |
15.84
|
-6.78 |
-6.10 |
|
PGQPPLINI |
15.91
|
-5.63 |
-4.95 |
|
PLLPPLPGQ |
17.36
|
-5.42 |
-4.74 |
| P39113 |
PRRPQKNRY |
11.91
|
-7.03 |
-6.35 |
|
FTHPEGPNC |
12.30
|
-5.50 |
-4.82 |
|
PPPPHKDHL |
13.33
|
-4.62 |
-3.94 |
| P40073 |
GYPQQQPSH |
17.13
|
-3.97 |
-3.29 |
| P25604 |
PPKPKSPHL |
12.99
|
-5.38 |
-4.70 |
|
KPKSPHLKP |
14.77
|
-6.04 |
-5.36 |
|
HLKPPLPPP |
15.48
|
-8.10 |
-7.42 |
| P25623 |
PVEPASPSI |
17.57
|
-4.67 |
-3.99 |
| Q05933 |
PVDPNTDRM |
13.84
|
-4.87 |
-4.19 |
|
TPGFPLNNV |
16.16
|
-4.97 |
-4.29 |
|
FTLPGTPGF |
16.18
|
-5.05 |
-4.37 |
| P53094 |
DEDPVSPKP |
14.57
|
-5.77 |
-5.09 |
|
FPQSPIRAY |
15.91
|
-5.31 |
-4.63 |
|
PLPPQTREP |
15.93
|
-4.97 |
-4.29 |
| Q12451 |
AAPKHAPPP |
16.17
|
-6.12 |
-5.44 |
|
HLLPWLPPT |
16.42
|
-5.55 |
-4.87 |
|
HAPPPVPNE |
17.17
|
-5.16 |
-4.48 |
| P15891 |
RRATPEKKP |
12.09
|
-6.71 |
-6.03 |
|
ISPKPFSKP |
13.83
|
-6.59 |
-5.91 |
|
QPPLPSRNV |
14.71
|
-5.60 |
-4.92 |
| P48562 |
PLNPYRPHH |
11.98
|
-5.31 |
-4.63 |
|
GQFPRGPMH |
12.40
|
-6.83 |
-6.15 |
|
NPYRPHHNM |
12.44
|
-7.54 |
-6.86 |
| Q08912 |
YTPSWGPSP |
12.93
|
-5.53 |
-4.85 |
|
GDHPKGPPP |
16.23
|
-5.88 |
-5.20 |
|
VCYTPSWGP |
17.70
|
-4.69 |
-4.01 |
| P17555 |
RPKKPSTLK |
14.75
|
-5.97 |
-5.29 |
|
SGPPPRPKK |
15.52
|
-4.81 |
-4.13 |
|
PKKPSTLKT |
16.87
|
-4.44 |
-3.76 |
| P47068 |
NTAPPLPRA |
14.63
|
-4.85 |
-4.17 |
|
YHPMPNTAP |
14.79
|
-8.22 |
-7.54 |
|
PFVDPSSNP |
15.08
|
-4.07 |
-3.39 |
| P38822 |
RGPAPEVPP |
17.06
|
-6.00 |
-5.32 |
| P04050 |
SYSPTSPNY |
13.26
|
-3.92 |
-3.24 |
|
NYSPTSPSY |
14.99
|
-4.54 |
-3.86 |
|
SPTSPGYSP |
15.64
|
-3.18 |
-2.50 |
| P40450 |
SSPKLFPRL |
12.18
|
-5.56 |
-4.88 |
|
LVTPPAPPL |
16.75
|
-6.96 |
-6.28 |
|
PKLFPRLSS |
17.45
|
-4.51 |
-3.83 |
| P40453 |
PDLPIRLRK |
14.14
|
-4.58 |
-3.90 |
|
VPEPPSWKP |
15.04
|
-6.23 |
-5.55 |
|
WKPPDLPIR |
15.95
|
-6.13 |
-5.45 |
| Q12168 |
QHPVPKPNI |
15.12
|
-6.34 |
-5.66 |
|
NDDPYFPQF |
15.28
|
-6.79 |
-6.11 |
|
DPYFPQFRS |
15.56
|
-2.81 |
-2.13 |
| P41832 |
PPPPPMALF |
17.11
|
-7.22 |
-6.54 |
| P36006 |
MGQPKDPKF |
12.53
|
-6.53 |
-5.85 |
|
PPPMGQPKD |
17.49
|
-3.57 |
-2.89 |
|
KPKNPGGLS |
17.55
|
-3.62 |
-2.94 |
| P38753 |
SPPVPGPAL |
15.74
|
-4.15 |
-3.47 |
|
PSNLPIQHP |
16.26
|
-5.78 |
-5.10 |
|
HISPPVPGP |
16.99
|
-6.88 |
-6.20 |
| P38237 |
VPPPNVPKK |
17.18
|
-4.25 |
-3.57 |
| P34245 |
YSTPFGPWP |
11.97
|
-6.08 |
-5.40 |
|
FGPWPGPAE |
17.54
|
-3.25 |
-2.57 |
|
PWPGPAECL |
17.73
|
-3.94 |
-3.26 |
| Q01389 |
RRYPQTPSY |
12.95
|
-6.05 |
-5.37 |
|
RPVPPDSSY |
14.32
|
-7.45 |
-6.77 |
|
YPQTPSYYY |
14.48
|
-6.97 |
-6.29 |
| Q03306 |
NKSIPRTKP |
12.62
|
-7.07 |
-6.39 |
|
SIPRTKPNV |
14.70
|
-5.61 |
-4.93 |
|
GEEKPFRIP |
14.88
|
-6.23 |
-5.55 |
| P34758 |
HSQPNKPNY |
11.76
|
-6.41 |
-5.73 |
|
LSSSPSPNP |
14.09
|
-4.66 |
-3.98 |
|
QPNKPNYGM |
16.67
|
-6.98 |
-6.30 |
| P53933 |
VAPPPLPNR |
14.10
|
-5.64 |
-4.96 |
|
PPIPSTQKP |
16.70
|
-4.93 |
-4.25 |
|
YNDLPMELP |
16.92
|
-8.35 |
-7.67 |
| P32381 |
LTEPPMNPL |
17.48
|
-5.86 |
-5.18 |
| Q00453 |
YAPPYFPHP |
10.28
|
-8.18 |
-7.50 |
|
SAPIPLPHQ |
13.08
|
-5.16 |
-4.48 |
|
HQPPPLPIY |
15.40
|
-7.09 |
-6.41 |
| P40021 |
SHPPNHPHS |
13.69
|
-3.57 |
-2.89 |
|
PSTPSQMNY |
15.00
|
-4.63 |
-3.95 |
|
PLPPPARSQ |
15.26
|
-6.28 |
-5.60 |
| Q04439 |
PPPPPSSKP |
15.29
|
-6.55 |
-5.87 |
|
HSKKPAPPP |
15.45
|
-6.48 |
-5.80 |
|
SSKPKEPMF |
15.65
|
-7.82 |
-7.14 |
| Q12446 |
PPPPPHRHV |
12.38
|
-7.67 |
-6.99 |
|
RPLPQLPNR |
12.60
|
-4.81 |
-4.13 |
|
PPPPRASRP |
12.89
|
-5.91 |
-5.23 |
| Q01560 |
PPPPPGEHM |
11.09
|
-6.46 |
-5.78 |
|
HHQPPEPQP |
16.08
|
-5.97 |
-5.29 |
|
QPPEPQPYY |
16.64
|
-5.29 |
-4.61 |
| P53735 |
PPPPRTRSP |
14.47
|
-5.02 |
-4.34 |
|
VPPPPRTRS |
15.89
|
-4.93 |
-4.25 |
| P33334 |
NAIPGGPKF |
10.87
|
-6.58 |
-5.90 |
|
LFFDPSLNP |
12.80
|
-4.26 |
-3.58 |
|
PSLNPIPHF |
13.58
|
-5.35 |
-4.67 |
| P40523 |
LGAPPGTVP |
14.20
|
-5.82 |
-5.14 |
|
LAPPPHGPF |
15.16
|
-7.36 |
-6.68 |
|
APPPHGPFS |
16.64
|
-1.66 |
-0.98 |
| P40563 |
PSERPKRRA |
12.46
|
-4.24 |
-3.56 |
|
GMVNPGQLP |
14.81
|
-5.79 |
-5.11 |
|
RAPPPVPKK |
15.04
|
-6.77 |
-6.09 |
| Q08989 |
GDHPKGPPP |
16.23
|
-5.88 |
-5.20 |
| P37370 |
RPHMPSVRP |
9.64
|
-7.91 |
-7.23 |
|
KVPQNRPHM |
10.59
|
-6.32 |
-5.64 |
|
VSQMPKPRP |
12.11
|
-7.27 |
-6.59 |
| P39743 |
NATIPEDNP |
13.72
|
-6.00 |
-5.32 |
| Q03900 |
NTPSGAPKL |
16.32
|
-3.86 |
-3.18 |
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