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Matrix information:
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ADAN-name: MYO5_1ZUY-16.PDB
Scoring matrix: MYO5_1ZUY-16_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.92
Foldx random average score for Saccharomyces cerevisiae: 14.683 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1749163
Proteins after disorder filtering: 4667
Total fragments: 108211
Proteins after pattern filtering: 2179
Total fragments: 10856
Proteins after MINT filtering: 45
Total fragments: 567 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
14.92
|
0.22 |
0.00 |
| Best peptides |
RFPIPSRRF |
0.00
|
-3.63 |
-3.84 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPPLPGQPP |
10.92
|
-4.05 |
-4.26 |
|
NEPLLPPLP |
10.93
|
-2.94 |
-3.15 |
|
LLPPLPGQP |
13.81
|
-2.17 |
-2.38 |
| P39113 |
ASHRGPRRP |
9.35
|
-1.50 |
-1.72 |
|
MSPLGAPPP |
10.15
|
-3.25 |
-3.46 |
|
PRRPQKNRY |
10.82
|
-2.11 |
-2.32 |
| P40073 |
GYPQQQPSH |
11.17
|
-1.84 |
-2.06 |
|
FDGYPQQQP |
11.87
|
-1.54 |
-1.76 |
| P25604 |
KPKSPHLKP |
11.66
|
-1.61 |
-1.83 |
|
QAPSLPPKP |
11.69
|
-1.09 |
-1.31 |
|
LPPKPKSPH |
12.39
|
-3.48 |
-3.69 |
| P25623 |
SSNLPKTVP |
11.42
|
-2.13 |
-2.34 |
|
QTFTPSEVP |
11.96
|
-0.48 |
-0.69 |
|
PLPVEPASP |
13.06
|
-2.22 |
-2.44 |
| Q05933 |
NFTLPGTPG |
11.04
|
-3.30 |
-3.51 |
|
TKFRGPAYP |
11.52
|
-0.91 |
-1.13 |
|
TFPVDPNTD |
13.81
|
-2.49 |
-2.71 |
| P53094 |
AFPQSPIRA |
10.21
|
-1.76 |
-1.98 |
|
REPNEPPPP |
12.16
|
-2.37 |
-2.59 |
|
YPLKLPPLP |
12.53
|
-4.02 |
-4.23 |
| Q12451 |
PHLLPWLPP |
10.90
|
-2.21 |
-2.42 |
|
AAPKHAPPP |
12.04
|
-1.72 |
-1.94 |
|
QPHLLPWLP |
14.00
|
-3.28 |
-3.49 |
| P15891 |
RRATPEKKP |
8.08
|
-1.67 |
-1.89 |
|
KSFTPSKSP |
8.72
|
-1.26 |
-1.48 |
|
ISPKPFSKP |
9.53
|
-1.62 |
-1.84 |
| P48562 |
KPPISAPRA |
8.94
|
-3.32 |
-3.53 |
|
QFPRGPMHP |
9.51
|
-2.42 |
-2.63 |
|
QNIGPAPRP |
9.56
|
-0.64 |
-0.85 |
| P40341 |
KPPLNDPSN |
12.04
|
-5.16 |
-5.38 |
|
SRNIPPPPP |
13.13
|
-2.91 |
-3.13 |
|
PLNDPSNPV |
14.13
|
0.47 |
0.26 |
| Q08912 |
YTPSWGPSP |
10.47
|
-1.71 |
-1.93 |
|
VCYTPSWGP |
11.15
|
-1.71 |
-1.93 |
|
DHPKGPPPP |
13.12
|
-1.00 |
-1.22 |
| P17555 |
RPKKPSTLK |
10.71
|
-4.07 |
-4.29 |
|
SKSGPPPRP |
11.74
|
-1.19 |
-1.41 |
|
PAPPASVFE |
14.31
|
0.99 |
0.78 |
| Q12342 |
RKAKAPPPP |
10.80
|
-3.48 |
-3.69 |
|
KAKAPPPPP |
14.37
|
-1.92 |
-2.13 |
| P47068 |
YHPMPNTAP |
7.68
|
-3.91 |
-4.13 |
|
PFVDPSSNP |
10.36
|
-1.09 |
-1.31 |
|
PSSNPFFRK |
10.49
|
-0.42 |
-0.64 |
| P38822 |
APEVPPPRR |
12.73
|
-2.49 |
-2.71 |
|
RGPAPEVPP |
13.16
|
-0.91 |
-1.13 |
|
VGDTPTTTP |
13.36
|
-0.87 |
-1.09 |
| P04050 |
PPVRPSISF |
10.31
|
-3.84 |
-4.05 |
|
NYSPTSPSY |
11.41
|
-1.37 |
-1.59 |
|
GSPAYSPKQ |
12.30
|
0.54 |
0.33 |
| P40450 |
KLPQLPPPP |
12.41
|
-2.19 |
-2.40 |
|
VSSSPKLFP |
12.50
|
-0.11 |
-0.33 |
|
PPPLPDLFK |
13.45
|
-2.57 |
-2.78 |
| P40453 |
RLRKRPPPP |
11.13
|
-4.41 |
-4.63 |
|
LRKRPPPPP |
12.08
|
-4.04 |
-4.25 |
|
WKPPDLPIR |
12.14
|
-1.19 |
-1.41 |
| Q12168 |
KVQHPVPKP |
11.81
|
-1.36 |
-1.58 |
|
NDDPYFPQF |
13.58
|
-1.30 |
-1.52 |
|
PLPPRANVQ |
14.55
|
-0.28 |
-0.50 |
| P41832 |
LSSQPPPPP |
13.54
|
-1.36 |
-1.58 |
|
PPPLPSVLS |
13.75
|
-3.14 |
-3.36 |
|
KGETPPPPP |
13.98
|
-1.86 |
-2.08 |
| P36006 |
KSNKKPKNP |
11.80
|
-1.85 |
-2.06 |
|
MGQPKDPKF |
12.07
|
-2.39 |
-2.61 |
|
NIPIPPPPP |
12.80
|
-3.85 |
-4.07 |
| P38753 |
YSPYPSNLP |
8.73
|
-2.23 |
-2.44 |
|
NLPIQHPTN |
10.07
|
-3.38 |
-3.59 |
|
PSNLPIQHP |
11.76
|
-2.00 |
-2.21 |
| P38237 |
NFQIPSKPE |
9.37
|
-1.49 |
-1.71 |
|
ENFQIPSKP |
13.52
|
-0.12 |
-0.33 |
|
IPSKPENTV |
14.20
|
-0.47 |
-0.68 |
| P34245 |
YSTPFGPWP |
11.20
|
-2.27 |
-2.48 |
|
FGPWPGPAE |
11.43
|
0.23 |
0.02 |
|
AYSTPFGPW |
12.01
|
-1.07 |
-1.29 |
| Q01389 |
YPQTPSYYY |
9.52
|
-3.68 |
-3.90 |
|
RYPQTPSYY |
10.07
|
-4.36 |
-4.58 |
|
NIPSPSSSP |
10.50
|
-0.74 |
-0.95 |
| Q03306 |
NKSIPRTKP |
7.61
|
-3.50 |
-3.71 |
|
PFRIPSSTK |
8.70
|
-3.52 |
-3.73 |
|
LGTVPSTTP |
9.59
|
-1.84 |
-2.06 |
| P34758 |
QSIKPSSTP |
8.62
|
-1.15 |
-1.37 |
|
LSSSPSPNP |
9.55
|
-0.87 |
-1.09 |
|
NQQQPQHLP |
9.87
|
-0.90 |
-1.12 |
| P53933 |
YNDLPMELP |
9.12
|
-4.85 |
-5.06 |
|
PPPIPSTQK |
11.86
|
-3.48 |
-3.69 |
|
KRVAPPPLP |
12.93
|
-1.82 |
-2.04 |
| P32381 |
LLTEPPMNP |
12.67
|
-1.37 |
-1.59 |
| Q00453 |
YFPHPMPSA |
9.64
|
-3.43 |
-3.65 |
|
SAPIPLPHQ |
9.74
|
-1.37 |
-1.59 |
|
YAPPYFPHP |
10.29
|
-2.22 |
-2.44 |
| P40021 |
NYVISPNLP |
10.28
|
-2.30 |
-2.51 |
|
SESHPPNHP |
12.18
|
-0.97 |
-1.19 |
|
LDFLPSTPS |
12.36
|
-3.02 |
-3.23 |
| P36150 |
PIVVNPSSP |
14.31
|
-2.25 |
-2.46 |
| Q04439 |
RHSKKPAPP |
11.07
|
-1.89 |
-2.11 |
|
HSKKPAPPP |
11.90
|
-1.87 |
-2.09 |
|
QANIPPPPP |
12.13
|
-3.28 |
-3.49 |
| Q12446 |
PFPVPQQQF |
9.45
|
-3.47 |
-3.69 |
|
QSQIPQSAP |
10.11
|
-2.60 |
-2.81 |
|
FAPLPDPPQ |
10.29
|
-3.19 |
-3.40 |
| Q01560 |
QPPEPQPYY |
12.12
|
-1.54 |
-1.76 |
|
HHQPPEPQP |
12.46
|
-0.26 |
-0.47 |
|
PEPQPYYPP |
12.86
|
-0.66 |
-0.88 |
| P00950 |
RSFDVPPPP |
14.38
|
-2.01 |
-2.22 |
| P53735 |
PAPKLVPPP |
13.41
|
-2.08 |
-2.29 |
|
PKLVPPPPR |
14.22
|
-2.86 |
-3.07 |
|
LVPPPPRTR |
14.58
|
-2.72 |
-2.94 |
| P33334 |
LFFDPSLNP |
8.86
|
-1.64 |
-1.86 |
|
NAIPGGPKF |
10.70
|
-1.95 |
-2.17 |
|
NNAIPGGPK |
10.79
|
-1.89 |
-2.11 |
| P40523 |
YMHNSPRNP |
9.21
|
-2.98 |
-3.19 |
|
GGPLASPTH |
10.36
|
-2.73 |
-2.94 |
|
ENITPLPTP |
11.68
|
-0.38 |
-0.59 |
| P40563 |
PSERPKRRA |
8.62
|
-1.89 |
-2.11 |
|
GMVNPGQLP |
10.68
|
-1.42 |
-1.64 |
|
VTPKVPERP |
12.45
|
-1.10 |
-1.32 |
| Q08989 |
DHPKGPPPP |
13.12
|
-1.00 |
-1.22 |
|
NGDHPKGPP |
13.57
|
-0.70 |
-0.91 |
| P37370 |
RPHMPSVRP |
6.14
|
-4.23 |
-4.45 |
|
VSQMPKPRP |
7.64
|
-3.13 |
-3.34 |
|
QMPKPRPFQ |
9.33
|
-1.94 |
-2.15 |
| P39743 |
NATIPEDNP |
9.91
|
-2.40 |
-2.61 |
|
AYSNPLTSP |
10.94
|
-1.16 |
-1.38 |
|
SNPLTSPVA |
11.43
|
-1.83 |
-2.04 |
| Q03900 |
LPNTPSGAP |
11.41
|
-2.02 |
-2.23 |
|
HLPNTPSGA |
14.63
|
-1.10 |
-1.32 |
|
