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Matrix information:
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ADAN-name: MYO5_1ZUY-14.PDB
Scoring matrix: MYO5_1ZUY-14_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.42
Foldx random average score for Saccharomyces cerevisiae: 15.719 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1744644
Proteins after disorder filtering: 4630
Total fragments: 91167
Proteins after pattern filtering: 2155
Total fragments: 10276
Proteins after MINT filtering: 42
Total fragments: 533 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
17.42
|
8.38 |
0.00 |
| Best peptides |
RPPRIYEGK |
0.00
|
-0.63 |
-9.01 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PLLPPLPGQ |
12.24
|
0.35 |
-8.03 |
|
PPLPGQPPL |
13.58
|
-1.13 |
-9.51 |
|
PNEPLLPPL |
14.75
|
-0.08 |
-8.46 |
| P39113 |
GPRRPQKNR |
8.39
|
1.78 |
-6.60 |
|
HRGPRRPQK |
11.28
|
3.87 |
-4.51 |
|
RGPRRPQKN |
13.24
|
0.41 |
-7.97 |
| P40073 |
YPQQQPSHT |
14.49
|
2.48 |
-5.90 |
| P25604 |
LPPKPNTQL |
10.55
|
0.86 |
-7.52 |
|
TPPLPPKPK |
11.16
|
-0.35 |
-8.73 |
|
KSPHLKPPL |
11.57
|
0.15 |
-8.23 |
| P25623 |
QPPLQPQSK |
10.53
|
0.34 |
-8.04 |
|
LPKTVPISI |
10.95
|
1.36 |
-7.02 |
|
PPLQPQSKT |
12.67
|
3.36 |
-5.02 |
| Q05933 |
FPVDPNTDR |
11.67
|
3.11 |
-5.27 |
|
LPGTPGFPL |
12.34
|
-0.16 |
-8.54 |
|
TPGFPLNNV |
12.94
|
3.84 |
-4.54 |
| P53094 |
FPQSPIRAY |
12.48
|
1.52 |
-6.86 |
|
CYPLKLPPL |
12.69
|
-1.87 |
-10.25 |
|
PVSPKPVSK |
12.98
|
3.50 |
-4.88 |
| Q12451 |
LPWLPPTDT |
13.41
|
1.51 |
-6.87 |
|
APKHAPPPV |
14.65
|
0.86 |
-7.52 |
|
APPPVPNET |
14.66
|
3.59 |
-4.79 |
| P15891 |
RATPEKKPK |
9.59
|
-0.79 |
-9.17 |
|
VPEDEPEGE |
11.07
|
2.31 |
-6.07 |
|
PPPPPRRAT |
11.51
|
2.11 |
-6.27 |
| P48562 |
NPYRPHHNM |
8.33
|
0.83 |
-7.55 |
|
SPSPLNPYR |
12.10
|
3.70 |
-4.68 |
|
KPPISAPRA |
12.44
|
0.49 |
-7.89 |
| P40341 |
PPPPPKPPL |
11.82
|
-1.73 |
-10.11 |
|
NDPSNPVSK |
11.93
|
3.94 |
-4.44 |
|
PPPPPPPPK |
11.97
|
-1.31 |
-9.69 |
| Q08912 |
PPPPPPDEK |
11.94
|
1.62 |
-6.76 |
|
PPPPDEKDR |
12.46
|
2.56 |
-5.82 |
|
TPSWGPSPM |
13.34
|
1.33 |
-7.05 |
| P17555 |
RPKKPSTLK |
10.42
|
-0.50 |
-8.88 |
|
PPPRPKKPS |
11.05
|
-0.36 |
-8.74 |
|
SGPPPRPKK |
11.47
|
3.16 |
-5.22 |
| Q12342 |
TPSTPSDGG |
12.26
|
1.73 |
-6.65 |
| P47068 |
PSSNPFFRK |
10.21
|
3.79 |
-4.59 |
|
EPISPETKK |
11.52
|
3.64 |
-4.74 |
|
DPSSNPFFR |
11.56
|
5.16 |
-3.22 |
| P38822 |
APEVPPPRR |
10.46
|
0.42 |
-7.96 |
|
PAPEVPPPR |
12.90
|
0.20 |
-8.18 |
| P04050 |
PPPPVRPSI |
11.17
|
0.93 |
-7.45 |
|
PGSPAYSPK |
11.82
|
1.41 |
-6.97 |
|
APTSPGFGV |
12.54
|
1.75 |
-6.63 |
| P40450 |
SSPKLFPRL |
10.74
|
3.84 |
-4.54 |
|
PPPLPDLFK |
10.84
|
0.68 |
-7.70 |
|
PAPPLPNGL |
12.11
|
-0.17 |
-8.55 |
| P40453 |
PDLPIRLRK |
9.82
|
3.67 |
-4.71 |
|
KPPDLPIRL |
11.42
|
2.28 |
-6.10 |
|
KVPEPPSWK |
12.43
|
2.90 |
-5.48 |
| Q12168 |
PPVPNRPGG |
10.87
|
-0.03 |
-8.41 |
|
PPLPPRANV |
11.42
|
2.12 |
-6.26 |
|
QHPVPKPNI |
11.97
|
2.07 |
-6.31 |
| P41832 |
PPPPPVPAK |
11.51
|
1.72 |
-6.66 |
|
PPPPVPAKL |
12.78
|
1.04 |
-7.34 |
|
PPPPPPMAL |
13.06
|
0.11 |
-8.27 |
| P36006 |
KKPKNPGGL |
8.65
|
-0.82 |
-9.20 |
|
PMGQPKDPK |
9.98
|
-0.11 |
-8.49 |
|
PPPPPPMGQ |
12.11
|
-0.43 |
-8.81 |
| P38753 |
SPPVPGPAL |
12.19
|
1.84 |
-6.54 |
|
TPVMPPQRQ |
13.21
|
2.37 |
-6.01 |
|
LPIQHPTNS |
14.25
|
2.96 |
-5.42 |
| P38237 |
VPPPNVPKK |
11.54
|
1.79 |
-6.59 |
|
DPFVPPPNV |
12.20
|
2.97 |
-5.41 |
|
FVPPPNVPK |
12.80
|
0.49 |
-7.89 |
| P34245 |
AYSTPFGPW |
12.69
|
-0.39 |
-8.77 |
|
PWPGPAECL |
14.88
|
2.67 |
-5.71 |
| Q01389 |
RYPQTPSYY |
11.86
|
-0.67 |
-9.05 |
|
SPSYPSIFR |
12.37
|
3.84 |
-4.54 |
|
ASPTSPKSL |
12.72
|
2.93 |
-5.45 |
| Q03306 |
SIPRTKPNV |
9.88
|
2.52 |
-5.86 |
|
KPFRIPSST |
10.06
|
2.64 |
-5.74 |
|
RQPTPSPPL |
11.55
|
-2.30 |
-10.68 |
| P34758 |
QPNKPNYGM |
8.95
|
-1.08 |
-9.46 |
|
PPPPPRAQQ |
12.13
|
1.50 |
-6.88 |
|
LVPTQPSYT |
12.94
|
3.04 |
-5.34 |
| P53933 |
PPPIPSTQK |
9.35
|
-0.15 |
-8.53 |
|
VAPPPLPNR |
11.91
|
1.65 |
-6.73 |
|
PPPLPNRQL |
11.93
|
0.90 |
-7.48 |
| Q00453 |
APPYFPHPM |
12.09
|
-0.20 |
-8.58 |
|
VPYNLPIST |
12.89
|
3.89 |
-4.49 |
|
PLPHQPPPL |
13.63
|
-0.15 |
-8.53 |
| P40021 |
SPPLPPPAR |
10.80
|
0.15 |
-8.23 |
|
FLPSTPSQM |
12.26
|
2.64 |
-5.74 |
|
LPPPLFPSS |
12.71
|
1.99 |
-6.39 |
| Q04439 |
PPPPGMQNK |
9.97
|
0.31 |
-8.07 |
|
KPAPPPPGM |
10.27
|
-1.25 |
-9.63 |
|
NIPTPPQNR |
10.74
|
1.85 |
-6.53 |
| Q12446 |
RPLPQLPNR |
8.44
|
-0.01 |
-8.39 |
|
PPPPPRASR |
9.53
|
-1.44 |
-9.82 |
|
PQLPNRNNR |
10.22
|
2.63 |
-5.75 |
| Q01560 |
QPPEPQPYY |
13.15
|
2.54 |
-5.84 |
|
YYPPPPPGE |
13.35
|
1.95 |
-6.43 |
|
PPSNAPIYE |
13.51
|
3.16 |
-5.22 |
| P00950 |
SFDVPPPPI |
14.65
|
-0.61 |
-8.99 |
|
VPPPPIDAS |
14.86
|
1.75 |
-6.63 |
| P53735 |
PKLVPPPPR |
11.76
|
-1.09 |
-9.47 |
|
VPPPPRTRS |
13.10
|
1.42 |
-6.96 |
|
KLVPPPPRT |
15.14
|
3.57 |
-4.81 |
| P33334 |
MPTRFPPAV |
10.58
|
1.50 |
-6.88 |
|
PPPPPPPGL |
11.01
|
-1.59 |
-9.97 |
|
KMPTRFPPA |
11.71
|
-1.23 |
-9.61 |
| P40523 |
PPGTVPNMQ |
12.30
|
2.16 |
-6.22 |
|
APPGTVPNM |
12.33
|
1.77 |
-6.61 |
|
SPRNPDTGT |
12.45
|
2.50 |
-5.88 |
| P40563 |
RAPPPVPKK |
11.47
|
0.88 |
-7.50 |
|
RRAPPPVPK |
11.56
|
-1.17 |
-9.55 |
|
PPPVPKKPS |
12.15
|
0.64 |
-7.74 |
| Q08989 |
PPPPDEKGR |
9.84
|
0.42 |
-7.96 |
|
PPPPPPDEK |
11.94
|
1.62 |
-6.76 |
|
PPPPPPPDE |
14.61
|
2.77 |
-5.61 |
| P37370 |
PKPRPFQNK |
6.42
|
1.41 |
-6.97 |
|
PPPTPTIGL |
9.11
|
-0.81 |
-9.19 |
|
KVPQNRPHM |
10.53
|
-1.08 |
-9.46 |
| Q03900 |
HLPNTPSGA |
12.82
|
1.83 |
-6.55 |
|
TPSGAPKLK |
14.86
|
4.01 |
-4.37 |
|
PNTPSGAPK |
14.93
|
2.27 |
-6.11 |
|
