ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1ZUY-12.PDB
Scoring matrix: MYO5_1ZUY-12_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.01
Foldx random average score for Saccharomyces cerevisiae: 10.361

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1278177
Proteins after disorder filtering: 4528
 Total fragments: 61436
Proteins after pattern filtering: 2124
 Total fragments: 10714
Proteins after MINT filtering: 45
 Total fragments: 808

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.01

-0.48

0.00
Best peptides

YRIPPKWR

0.00

-2.94

-2.46
         
Interactors      
P53145

PLLPPLPG

8.38

-3.89

-3.41

PGQPPLIN

9.52

-2.84

-2.36

NEPLLPPL

9.71

-2.49

-2.01
P39113

PRRPQKNR

4.61

-2.70

-2.22

PPPPHKDH

6.65

-2.81

-2.33

HRGPRRPQ

6.74

-1.76

-1.28
P40073

GYPQQQPS

9.85

-2.84

-2.36

DGYPQQQP

9.87

-2.67

-2.19
P25604

PSLPPKPN

6.04

-3.67

-3.19

PPLPPKPK

6.99

-3.26

-2.78

KSPHLKPP

7.01

-1.58

-1.10
P25623

PHATPKNV

8.71

-0.95

-0.47

DTPPLPPH

9.07

-3.02

-2.54

SQPPLQPQ

9.07

-3.57

-3.09
Q05933

PGTPGFPL

8.54

-3.94

-3.46

FRGPAYPS

8.91

-1.47

-0.99

RGPAYPSN

9.78

-1.69

-1.21
P53094

DPVSPKPV

7.27

-3.30

-2.82

LKLPPLPL

7.27

-4.00

-3.52

CYPLKLPP

8.35

-3.62

-3.14
Q12451

PHLLPWLP

8.30

-3.39

-2.91

HLLPWLPP

8.78

-3.66

-3.18

PKHAPPPV

9.47

-2.66

-2.18
P15891

ATPEKKPK

6.68

-2.53

-2.05

KKEPVKTP

6.96

-1.40

-0.92

PEKKPKEN

7.04

-3.08

-2.60
P48562

MRQAPKRP

6.36

-1.90

-1.42

VAKPKKPA

6.40

-2.75

-2.27

IGPAPRPP

6.62

-2.64

-2.16
P40341

PPPPPKPP

6.42

-3.32

-2.84

RNIPPPPP

6.84

-2.99

-2.51

NIPPPPPP

8.52

-3.35

-2.87
Q08912

KGPPPPPP

8.21

-3.42

-2.94

CYTPSWGP

9.49

-3.40

-2.92

GPPPPPPP

9.54

-3.28

-2.80
P17555

SGPPPRPK

5.90

-3.15

-2.67

PPRPKKPS

6.73

-3.07

-2.59

PPPRPKKP

7.67

-2.88

-2.40
Q12342

KAPPPPPP

8.19

-3.51

-3.03

KAKAPPPP

8.97

-2.72

-2.24

AKAPPPPP

9.11

-2.27

-1.79
P47068

DKVPPHPV

7.52

-3.53

-3.05

YVPPGIPT

7.73

-2.41

-1.93

PSIPPVPP

7.88

-2.18

-1.70
P38822

PEVPPPRR

8.65

-3.92

-3.44
P04050

PAYSPKQD

7.55

-1.84

-1.36

PPPPVRPS

7.63

-2.94

-2.46

PVRPSISF

8.32

-2.14

-1.66
P40450

PKLFPRLS

6.77

-1.21

-0.73

SSPKLFPR

6.78

-3.93

-3.45

PAPPPLPD

7.74

-4.16

-3.68
P40453

WKPPDLPI

6.66

-4.26

-3.78

KRPPPPPP

6.67

-3.73

-3.25

RKRPPPPP

6.88

-3.34

-2.86
Q12168

QHPVPKPN

6.51

-1.76

-1.28

PYFPQFRS

6.60

-5.38

-4.90

RGPPPLPP

7.00

-4.31

-3.83
P41832

PAPPMMPA

7.31

-4.08

-3.60

GVIPPAPP

8.06

-2.10

-1.62

PPPPPMAL

8.30

-4.48

-4.00
P36006

SNKKPKNP

7.16

-2.14

-1.66

IPIPPPPP

8.13

-3.12

-2.64

ANIPIPPP

8.13

-2.75

-2.27
P38753

PVMPPQRQ

8.00

-4.11

-3.63

PYPSNLPI

9.05

-3.48

-3.00

AHISPPVP

9.24

-2.32

-1.84
P38237

FQIPSKPE

4.28

-3.34

-2.86

PFVPPPNV

9.04

-3.93

-3.45

PPNVPKKD

9.67

-0.39

0.09
P34245

STPFGPWP

7.53

-3.18

-2.70

TPFGPWPG

8.06

-2.92

-2.44

FGPWPGPA

9.86

-1.47

-0.99
Q01389

KREAPKPP

5.83

-2.75

-2.27

PPPIPKTA

7.20

-1.96

-1.48

EEAPTKPN

7.73

-2.51

-2.03
Q03306

EEKPFRIP

7.13

-3.11

-2.63

SIPRTKPN

7.16

-2.94

-2.46

EKPFRIPS

7.73

-1.76

-1.28
P34758

HSQPNKPN

7.15

-2.23

-1.75

GLQPLKPT

7.50

-2.33

-1.85

PPPPPRAQ

7.62

-2.49

-2.01
P53933

RRRPPPPP

6.34

-3.12

-2.64

RRPPPPPI

6.68

-3.31

-2.83

VAPPPLPN

7.62

-4.49

-4.01
P32381

LTEPPMNP

8.39

-2.82

-2.34

TEPPMNPL

10.25

-2.60

-2.12
Q00453

YAPPYFPH

5.92

-4.49

-4.01

YFPHPMPS

7.32

-3.32

-2.84

HQPPPLPI

7.45

-4.64

-4.16
P40021

LPPPLFPS

7.45

-5.15

-4.67

PLPPPLFP

8.12

-4.41

-3.93

GPPPPLPP

8.37

-3.82

-3.34
P36150

IVVNPSSP

9.65

-2.10

-1.62
Q04439

PPPSSKPK

7.44

-2.54

-2.06

ANIPPPPP

7.50

-2.89

-2.41

KKPAPPPP

7.86

-2.86

-2.38
Q12446

TNPFPFPV

6.41

-3.64

-3.16

SNPFPFPI

6.42

-3.57

-3.09

PPPPHRHV

6.65

-2.90

-2.42
Q01560

YYPPPPPG

7.91

-3.68

-3.20

PYYPPPPP

8.66

-3.64

-3.16

PEPQPYYP

9.08

-3.10

-2.62
P00950

FDVPPPPI

8.57

-3.82

-3.34

VPPPPIDA

9.18

-2.57

-2.09

DVPPPPID

9.38

-2.74

-2.26
P53735

VPPPPRTR

6.74

-2.85

-2.37

KLVPPPPR

7.74

-4.25

-3.77

LVPPPPRT

8.96

-3.25

-2.77
P33334

SKMPTRFP

5.74

-4.03

-3.55

KMPTRFPP

6.63

-3.86

-3.38

PPPPGFEE

7.90

-4.45

-3.97
P40523

VGVPPLAP

8.45

-4.29

-3.81

PPHGPFST

9.14

-2.91

-2.43

MHNSPRNP

9.20

-1.96

-1.48
P40563

PPVPKKPS

6.96

-3.61

-3.13

SEVTPKVP

7.56

-2.16

-1.68

PPPVPKKP

7.66

-2.30

-1.82
Q08989

KGPPPPPP

8.21

-3.42

-2.94

PPPPPPPP

9.49

-3.36

-2.88

GPPPPPPP

9.54

-3.28

-2.80
P37370

PKPRPFQN

6.60

-4.13

-3.65

QNRPHMPS

6.70

-4.20

-3.72

QMPKPRPF

6.71

-3.04

-2.56
P39743

ATIPEDNP

9.09

-1.78

-1.30
Q03900

PSGAPKLK

9.00

-0.86

-0.38

HLPNTPSG

10.04

-1.91

-1.43

 


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