ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-4.PDB
Scoring matrix: MYO5_1YP5-4_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.27
Foldx random average score for Saccharomyces cerevisiae: 16.391

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1336847
Proteins after disorder filtering: 4423
 Total fragments: 88950
Proteins after pattern filtering: 2294
 Total fragments: 21340
Proteins after MINT filtering: 45
 Total fragments: 1482

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.27

-5.12

0.00
Best peptides

RPPRRFRDRH

0.00

-6.85

-1.73
         
Interactors      
P53145

PLPGQPPLIN

10.83

-8.71

-3.59

PPLPGQPPLI

11.61

-8.51

-3.39

NEPLLPPLPG

13.05

-5.74

-0.62
P39113

ASHRGPRRPQ

8.74

-6.02

-0.90

PLGAPPPPPH

8.97

-10.49

-5.37

SPLGAPPPPP

9.19

-10.00

-4.88
P40073

QFDGYPQQQP

10.40

-6.25

-1.13

FDGYPQQQPS

12.57

-4.68

0.44

DGYPQQQPSH

14.82

-4.05

1.07
P25604

PLPPPPPPQP

8.97

-10.48

-5.36

PLPPKPKSPH

9.10

-8.09

-2.97

SPHLKPPLPP

9.27

-9.75

-4.63
P25623

TPSEVPPSTP

10.35

-8.60

-3.48

QPPLQPQSKT

10.70

-7.26

-2.14

TPPLPPHATP

11.17

-7.91

-2.79
Q05933

FPVDPNTDRM

10.62

-6.81

-1.69

FRGPAYPSNS

11.55

-6.15

-1.03

TLPGTPGFPL

12.21

-6.10

-0.98
P53094

FKSSAFPQSP

9.46

-6.60

-1.48

YPLKLPPLPL

9.57

-9.05

-3.93

REPNEPPPPC

10.61

-6.43

-1.31
Q12451

QPHLLPWLPP

9.87

-8.21

-3.09

APKHAPPPVP

10.03

-10.48

-5.36

PKHAPPPVPN

11.78

-7.36

-2.24
P15891

PPPPPRRATP

8.72

-8.88

-3.76

RSSAAPPPPP

9.47

-7.67

-2.55

APPPPPRRAT

9.59

-8.02

-2.90
P48562

SPLNPYRPHH

7.56

-7.84

-2.72

PPISAPRAPY

8.09

-6.69

-1.57

NIGPAPRPPS

8.18

-7.58

-2.46
P40341

NIPPPPPPPP

7.95

-8.72

-3.60

RNIPPPPPPP

8.37

-8.78

-3.66

PPPPPPPPKP

8.84

-11.31

-6.19
Q08912

HPKGPPPPPP

8.66

-10.46

-5.34

PPPPPPPDEK

9.26

-9.58

-4.46

PKGPPPPPPP

10.02

-9.53

-4.41
P17555

APPPPPPAPP

9.34

-10.15

-5.03

SKSGPPPRPK

10.18

-7.74

-2.62

APAPPPPPPA

10.70

-8.53

-3.41
Q12342

RKAKAPPPPP

7.76

-9.08

-3.96

APPPPPPPPP

8.84

-10.15

-5.03

AKAPPPPPPP

9.93

-8.36

-3.24
P47068

PLPRAPPVPP

7.94

-9.54

-4.42

TAPPLPRAPP

8.43

-8.82

-3.70

SIPPVPPTPP

9.50

-8.66

-3.54
P38822

PAPEVPPPRR

11.16

-7.92

-2.80

APEVPPPRRS

11.29

-8.28

-3.16

RGPAPEVPPP

12.05

-5.35

-0.23
P04050

CLPVPPPPVR

10.18

-7.88

-2.76

SPSYSPTSPN

10.74

-7.82

-2.70

SPSYSPTSPA

11.27

-7.93

-2.81
P40450

QLPPPPPPPP

8.44

-9.25

-4.13

PPPPPPPPPP

8.79

-10.56

-5.44

AVPPPPPPPP

9.65

-8.95

-3.83
P40453

RLRKRPPPPP

6.55

-9.43

-4.31

RKRPPPPPPV

8.91

-6.91

-1.79

RPPPPPPVSM

9.21

-7.79

-2.67
Q12168

PPPLPPRANV

9.77

-6.57

-1.45

TNRGPPPLPP

10.29

-10.87

-5.75

NKVQHPVPKP

10.50

-7.48

-2.36
P41832

QPPPPPPPPP

8.19

-9.90

-4.78

PPPPPPPPPP

8.79

-10.56

-5.44

APPPPPPPPP

8.84

-10.15

-5.03
P36006

NIPIPPPPPP

7.89

-8.95

-3.83

PPPPPPMGQP

8.64

-11.00

-5.88

PPMGQPKDPK

10.17

-9.50

-4.38
P38753

YPSNLPIQHP

10.41

-7.20

-2.08

PVMPPQRQSY

11.15

-5.50

-0.38

NTPVMPPQRQ

11.26

-6.55

-1.43
P38237

DLNDPFVPPP

10.19

-7.43

-2.31

FVPPPNVPKK

10.70

-5.21

-0.09

DPFVPPPNVP

11.32

-8.22

-3.10
P34245

TPFGPWPGPA

12.78

-6.33

-1.21

AYSTPFGPWP

12.97

-5.70

-0.58

PWPGPAECLW

13.65

-5.12

0.00
Q01389

SPSSSPPPIP

9.16

-10.40

-5.28

APKREAPKPP

9.67

-9.00

-3.88

EPSTPSRPVP

10.59

-6.39

-1.27
Q03306

RNKSIPRTKP

6.59

-9.14

-4.02

QPTPSPPLPQ

10.16

-7.74

-2.62

SIPRTKPNVP

10.18

-8.83

-3.71
P34758

PPPPPPRAQQ

7.73

-8.27

-3.15

QPQHLPPPPP

8.62

-8.82

-3.70

HLPPPPPPRA

10.19

-8.07

-2.95
P53933

RTRRRPPPPP

6.70

-11.76

-6.64

RRRPPPPPIP

7.65

-8.92

-3.80

TRRRPPPPPI

7.74

-7.28

-2.16
P32381

LLTEPPMNPL

12.40

-7.62

-2.50

ILLTEPPMNP

13.05

-8.14

-3.02
Q00453

APPYFPHPMP

8.59

-10.12

-5.00

FPHPMPSAPI

9.44

-7.39

-2.27

PIPLPHQPPP

9.78

-8.54

-3.42
P40021

PPPPLPPPLF

9.86

-9.57

-4.45

FLPSTPSQMN

10.01

-6.36

-1.24

PLPPPARSQS

10.64

-7.26

-2.14
P36150

NPIVVNPSSP

12.54

-6.26

-1.14

PIVVNPSSPS

13.51

-6.74

-1.62
Q04439

NIPPPPPPPP

7.95

-8.72

-3.60

RQANIPPPPP

8.15

-7.93

-2.81

IPPPPPPPPP

10.07

-10.93

-5.81
Q12446

RPVPPPPPMR

7.36

-9.93

-4.81

RLPAPPPPPR

7.38

-8.10

-2.98

RRGPAPPPPP

7.85

-9.84

-4.72
Q01560

PQPYYPPPPP

8.78

-8.77

-3.65

YYPPPPPGEH

8.95

-8.71

-3.59

QPYYPPPPPG

9.02

-10.19

-5.07
P00950

RSFDVPPPPI

9.86

-7.38

-2.26

SFDVPPPPID

12.36

-7.08

-1.96

RRSFDVPPPP

13.32

-7.77

-2.65
P53735

APKLVPPPPR

9.83

-9.05

-3.93

LVPPPPRTRS

11.42

-5.71

-0.59

PKLVPPPPRT

11.43

-7.68

-2.56
P33334

MPTRFPPAVF

7.90

-8.82

-3.70

FLPPPPPPPS

8.92

-8.27

-3.15

ALPPPPPPPP

9.09

-10.33

-5.21
P40523

YMHNSPRNPD

9.19

-5.48

-0.36

TPLPTPVPVP

10.52

-8.35

-3.23

NITPLPTPVP

10.69

-8.52

-3.40
P40563

PKRRAPPPVP

8.83

-9.27

-4.15

RRAPPPVPKK

8.87

-6.01

-0.89

PSERPKRRAP

10.99

-5.75

-0.63
Q08989

HPKGPPPPPP

8.66

-10.46

-5.34

PPPPPPPDEK

9.26

-9.58

-4.46

PKGPPPPPPP

10.02

-9.53

-4.41
P37370

NPPQAPPPPP

8.26

-10.32

-5.20

MPAPPPPPPP

8.50

-11.04

-5.92

NPTKSPPPPP

8.52

-10.79

-5.67
P39743

PNATIPEDNP

14.05

-7.81

-2.69

PAYSNPLTSP

15.15

-6.22

-1.10
Q03900

TPSGAPKLKN

10.73

-7.20

-2.08

HLPNTPSGAP

12.33

-5.92

-0.80

NTPSGAPKLK

14.08

-5.49

-0.37

 


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