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Matrix information:
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ADAN-name: MYO5_1YP5-29.PDB
Scoring matrix: MYO5_1YP5-29_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 16.62
Foldx random average score for Saccharomyces cerevisiae: 11.647 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3200363
Proteins after random average filtering: 7179
Total fragments: 1259255
Proteins after disorder filtering: 3925
Total fragments: 41422
Proteins after pattern filtering: 1953
Total fragments: 9876
Proteins after MINT filtering: 41
Total fragments: 552 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
16.62
|
1.03 |
0.00 |
| Best peptides |
DYPPIMPWWH |
0.00
|
-8.12 |
-9.15 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LLPPLPGQPP |
6.86
|
-7.36 |
-8.39 |
|
NEPLLPPLPG |
7.68
|
-8.06 |
-9.09 |
|
PLPGQPPLIN |
8.62
|
-5.59 |
-6.62 |
| P39113 |
HRGPRRPQKN |
6.79
|
-8.04 |
-9.07 |
|
PRRPQKNRYN |
7.28
|
-5.76 |
-6.79 |
|
RGPRRPQKNR |
8.47
|
-6.03 |
-7.06 |
| P40073 |
GYPQQQPSHT |
11.08
|
-4.22 |
-5.25 |
|
QFDGYPQQQP |
11.17
|
-3.77 |
-4.80 |
| P25604 |
NTPPLPPKPK |
6.55
|
-6.63 |
-7.66 |
|
QAPSLPPKPN |
7.45
|
-6.98 |
-8.01 |
|
PLPPKPKSPH |
7.64
|
-7.04 |
-8.07 |
| P25623 |
DTPPLPPHAT |
7.35
|
-6.57 |
-7.60 |
|
SQPPLQPQSK |
7.89
|
-5.48 |
-6.51 |
|
PLPPHATPKN |
8.90
|
-3.53 |
-4.56 |
| Q05933 |
TLPGTPGFPL |
7.86
|
-6.77 |
-7.80 |
|
GTPGFPLNNV |
9.07
|
-6.50 |
-7.53 |
|
TKFRGPAYPS |
9.69
|
-4.20 |
-5.23 |
| P53094 |
YPLKLPPLPL |
7.28
|
-7.56 |
-8.59 |
|
KLPPLPLTSD |
8.60
|
-6.20 |
-7.23 |
|
LNVPLPPQTR |
8.63
|
-6.01 |
-7.04 |
| Q12451 |
LLPWLPPTDT |
8.41
|
-6.64 |
-7.67 |
|
HLLPWLPPTD |
8.98
|
-4.94 |
-5.97 |
|
QPHLLPWLPP |
10.28
|
-4.03 |
-5.06 |
| P15891 |
AQPPLPSRNV |
6.06
|
-8.68 |
-9.71 |
|
AAPPPPPRRA |
8.83
|
-6.90 |
-7.93 |
|
PRRATPEKKP |
8.86
|
-5.95 |
-6.98 |
| P48562 |
LNPYRPHHNM |
7.65
|
-6.69 |
-7.72 |
|
PYRPHHNMIN |
7.92
|
-5.62 |
-6.65 |
|
PSPLNPYRPH |
7.98
|
-5.34 |
-6.37 |
| P40341 |
PPPPKPPLND |
8.23
|
-5.56 |
-6.59 |
|
PKPPLNDPSN |
9.62
|
-5.56 |
-6.59 |
|
PPPPPPPKPP |
10.31
|
-6.52 |
-7.55 |
| Q08912 |
PPPPPDEKDR |
10.85
|
-2.73 |
-3.76 |
|
GPPPPPPPDE |
11.46
|
-4.58 |
-5.61 |
|
YTPSWGPSPM |
11.52
|
-3.41 |
-4.44 |
| P17555 |
GPPPRPKKPS |
7.17
|
-6.53 |
-7.56 |
|
PRPKKPSTLK |
9.10
|
-6.08 |
-7.11 |
|
SKSGPPPRPK |
9.63
|
-5.22 |
-6.25 |
| P47068 |
VPPGIPTNDT |
8.43
|
-8.14 |
-9.17 |
|
PLPPVSEEYH |
8.62
|
-3.50 |
-4.53 |
|
VDPSSNPFFR |
9.00
|
-3.10 |
-4.13 |
| P38822 |
PAPEVPPPRR |
9.88
|
-5.32 |
-6.35 |
|
APEVPPPRRS |
10.37
|
-5.15 |
-6.18 |
|
DRGPAPEVPP |
11.34
|
-4.55 |
-5.58 |
| P04050 |
PVPPPPVRPS |
8.65
|
-6.12 |
-7.15 |
|
PPPVRPSISF |
8.80
|
-6.44 |
-7.47 |
|
GSPAYSPKQD |
9.61
|
-2.60 |
-3.63 |
| P40450 |
APPPLPDLFK |
6.68
|
-7.41 |
-8.44 |
|
SPKLFPRLSS |
8.04
|
-6.31 |
-7.34 |
|
SSPKLFPRLS |
8.14
|
-8.27 |
-9.30 |
| P40453 |
PDLPIRLRKR |
6.51
|
-7.26 |
-8.29 |
|
KPPDLPIRLR |
7.13
|
-8.27 |
-9.30 |
|
RLRKRPPPPP |
8.44
|
-6.79 |
-7.82 |
| Q12168 |
DDPYFPQFRS |
6.80
|
-5.85 |
-6.88 |
|
GPPPLPPRAN |
6.87
|
-8.69 |
-9.72 |
|
IPPPVPNRPG |
8.00
|
-6.91 |
-7.94 |
| P41832 |
VIPPAPPMMP |
8.11
|
-7.88 |
-8.91 |
|
PPPPPMALFG |
8.99
|
-7.14 |
-8.17 |
|
ETPPPPPLPS |
9.51
|
-6.51 |
-7.54 |
| P36006 |
PIPPPPPPMG |
9.16
|
-7.50 |
-8.53 |
|
PPPPPMGQPK |
9.43
|
-4.88 |
-5.91 |
|
ANIPIPPPPP |
9.84
|
-6.70 |
-7.73 |
| P38753 |
NTPVMPPQRQ |
7.68
|
-6.67 |
-7.70 |
|
PYPSNLPIQH |
8.60
|
-5.61 |
-6.64 |
|
SNLPIQHPTN |
10.19
|
-4.77 |
-5.80 |
| P38237 |
ENFQIPSKPE |
7.72
|
-6.53 |
-7.56 |
|
QIPSKPENTV |
8.63
|
-6.24 |
-7.27 |
|
VPPPNVPKKD |
10.24
|
-3.64 |
-4.67 |
| P34245 |
YSTPFGPWPG |
9.82
|
-4.49 |
-5.52 |
|
PFGPWPGPAE |
10.99
|
-4.24 |
-5.27 |
| Q01389 |
ASPSYPSIFR |
7.37
|
-7.97 |
-9.00 |
|
RYPQTPSYYY |
7.59
|
-7.24 |
-8.27 |
|
RSKPLPPQLL |
7.77
|
-6.01 |
-7.04 |
| Q03306 |
PSPPLPQMEF |
8.00
|
-7.48 |
-8.51 |
|
EKPFRIPSST |
9.26
|
-6.09 |
-7.12 |
|
TKPNVPPLQT |
9.37
|
-6.86 |
-7.89 |
| P34758 |
QLPLEPLKPT |
8.39
|
-5.30 |
-6.33 |
|
QQLPLEPLKP |
8.53
|
-7.01 |
-8.04 |
|
HLPPPPPPRA |
9.03
|
-5.51 |
-6.54 |
| P53933 |
APPPLPNRQL |
7.36
|
-8.17 |
-9.20 |
|
RRPPPPPIPS |
7.77
|
-5.79 |
-6.82 |
|
KRVAPPPLPN |
8.98
|
-6.64 |
-7.67 |
| P32381 |
ILLTEPPMNP |
9.70
|
-6.19 |
-7.22 |
| Q00453 |
YAPPYFPHPM |
8.18
|
-5.18 |
-6.21 |
|
SLYAPPYFPH |
8.26
|
-5.98 |
-7.01 |
|
PYFPHPMPSA |
8.35
|
-5.46 |
-6.49 |
| P40021 |
FLPSTPSQMN |
6.80
|
-6.24 |
-7.27 |
|
NSPPLPPPAR |
8.73
|
-6.21 |
-7.24 |
|
PPLPPPLFPS |
9.42
|
-6.08 |
-7.11 |
| Q04439 |
SSKPKEPMFE |
7.27
|
-5.03 |
-6.06 |
|
SKPKEPMFEA |
9.64
|
-5.41 |
-6.44 |
|
SKKPAPPPPG |
10.01
|
-4.88 |
-5.91 |
| Q12446 |
SLPPLPNQFA |
5.30
|
-8.42 |
-9.45 |
|
PLPQLPNRNN |
6.40
|
-8.05 |
-9.08 |
|
FPFPIPEIPS |
7.36
|
-6.16 |
-7.19 |
| Q01560 |
HQPPEPQPYY |
9.36
|
-4.91 |
-5.94 |
|
PQPYYPPPPP |
9.48
|
-6.69 |
-7.72 |
|
PPPPPGEHMH |
9.50
|
-6.04 |
-7.07 |
| P00950 |
RSFDVPPPPI |
10.29
|
-5.44 |
-6.47 |
| P53735 |
KLVPPPPRTR |
8.60
|
-5.65 |
-6.68 |
|
APKLVPPPPR |
9.48
|
-5.56 |
-6.59 |
|
PKLVPPPPRT |
10.60
|
-5.24 |
-6.27 |
| P33334 |
FDPSLNPIPH |
7.92
|
-4.88 |
-5.91 |
|
FLPPPPPPPS |
9.22
|
-6.76 |
-7.79 |
|
KMPTRFPPAV |
9.29
|
-5.89 |
-6.92 |
| P40523 |
GVPPLAPPPH |
9.09
|
-6.57 |
-7.60 |
|
APPPHGPFST |
9.32
|
-4.89 |
-5.92 |
|
APPGTVPNMQ |
10.23
|
-4.45 |
-5.48 |
| P40563 |
APPPVPKKPS |
8.34
|
-6.30 |
-7.33 |
|
KRRAPPPVPK |
9.32
|
-4.95 |
-5.98 |
|
RRAPPPVPKK |
10.84
|
-4.76 |
-5.79 |
| Q08989 |
GPPPPPPPPD |
11.12
|
-4.98 |
-6.01 |
|
PPPPPPPPDE |
11.42
|
-3.90 |
-4.93 |
| P37370 |
SQMPKPRPFQ |
7.70
|
-6.03 |
-7.06 |
|
MPKPRPFQNK |
7.70
|
-6.03 |
-7.06 |
|
PPPPLPAAMS |
7.73
|
-6.72 |
-7.75 |
|
