ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-27.PDB
Scoring matrix: MYO5_1YP5-27_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 9.94
Foldx random average score for Saccharomyces cerevisiae: 10.678

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1643126
Proteins after disorder filtering: 4698
 Total fragments: 116750
Proteins after pattern filtering: 2283
 Total fragments: 18019
Proteins after MINT filtering: 45
 Total fragments: 1176

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

9.94

-3.75

0.00
Best peptides

WDWEWDPRR

0.00

-5.70

-1.95
         
Interactors      
P53145

LPPLPGQPP

6.12

-5.79

-2.04

LPGQPPLIN

6.36

-5.85

-2.10

LLPPLPGQP

8.33

-2.29

1.46
P39113

RGPRRPQKN

3.84

-5.41

-1.66

LGAPPPPPH

4.05

-6.29

-2.54

LFTHPEGPN

5.49

-5.15

-1.40
P40073

FDGYPQQQP

8.79

-4.37

-0.62

DGYPQQQPS

9.33

-2.63

1.12

YPQQQPSHT

9.52

-2.62

1.13
P25604

LPPKPKSPH

4.18

-5.23

-1.48

LKPPLPPPP

5.08

-5.78

-2.03

LPPPPPPQP

5.21

-5.46

-1.71
P25623

LPVEPASPS

4.66

-5.60

-1.85

ISQPPLQPQ

6.11

-4.95

-1.20

FTPSEVPPS

6.76

-3.78

-0.03
Q05933

KFRGPAYPS

6.54

-4.27

-0.52

RGPAYPSNS

6.95

-2.96

0.79

FRGPAYPSN

8.23

-2.95

0.80
P53094

LKLPPLPLT

5.26

-5.16

-1.41

EPNEPPPPC

5.41

-4.17

-0.42

REPNEPPPP

5.74

-5.12

-1.37
Q12451

HLLPWLPPT

6.12

-4.59

-0.84

AAPKHAPPP

6.30

-4.18

-0.43

APKHAPPPV

7.61

-4.42

-0.67
P15891

RSSAAPPPP

5.22

-5.28

-1.53

ISPKPFSKP

5.38

-4.35

-0.60

AAPPPPPRR

5.44

-5.90

-2.15
P48562

IGPAPRPPS

4.02

-6.35

-2.60

MRQAPKRPD

4.26

-6.43

-2.68

QRTAPKPPI

5.57

-5.89

-2.14
P40341

RNIPPPPPP

3.51

-6.15

-2.40

IPPPPPPPP

4.69

-6.47

-2.72

NSRNIPPPP

6.30

-5.48

-1.73
Q08912

KGPPPPPPP

4.81

-6.28

-2.53

GPPPPPPPD

6.23

-5.56

-1.81

HPKGPPPPP

6.43

-5.38

-1.63
P17555

RPKKPSTLK

5.27

-3.75

-0.00

AAPAPPPPP

5.76

-6.16

-2.41

KSGPPPRPK

5.92

-5.06

-1.31
Q12342

RKAKAPPPP

4.19

-5.00

-1.25

KAKAPPPPP

5.21

-6.37

-2.62

KAPPPPPPP

5.50

-5.49

-1.74
P47068

LSAPSIPPV

5.44

-3.65

0.10

LSAPSVPPV

5.59

-3.83

-0.08

APPAPPAPL

6.12

-5.59

-1.84
P38822

RGPAPEVPP

6.36

-5.30

-1.55

PAPEVPPPR

8.18

-4.66

-0.91

GDTPTTTPG

8.43

-1.16

2.59
P04050

LPVPPPPVR

6.23

-4.34

-0.59

VPPPPVRPS

7.23

-4.74

-0.99

GSPAYSPKQ

7.63

-3.55

0.20
P40450

LPPPPPPPP

4.03

-6.62

-2.87

LVTPPAPPL

5.32

-5.55

-1.80

LPQLPPPPP

5.53

-6.26

-2.51
P40453

LRKRPPPPP

2.38

-6.93

-3.18

RKRPPPPPP

3.45

-6.17

-2.42

RLRKRPPPP

3.52

-5.47

-1.72
Q12168

RGPPPLPPR

3.42

-6.21

-2.46

IPPPVPNRP

6.61

-5.76

-2.01

GPPPLPPRA

7.11

-5.46

-1.71
P41832

LSSQPPPPP

3.42

-6.72

-2.97

QPPPPPPPP

5.76

-5.56

-1.81

DSPAPPPPP

5.81

-5.73

-1.98
P36006

IPIPPPPPP

4.87

-6.14

-2.39

MGQPKDPKF

5.46

-5.23

-1.48

IPPPPPPMG

5.65

-6.21

-2.46
P38753

LPIQHPTNS

7.36

-3.74

0.01

ISPPVPGPA

7.52

-4.31

-0.56

TPVMPPQRQ

8.09

-5.80

-2.05
P38237

LNDPFVPPP

5.23

-4.34

-0.59

IPSKPENTV

6.99

-3.45

0.30

FQIPSKPEN

7.25

-2.42

1.33
P34245

YSTPFGPWP

7.74

-4.22

-0.47

FGPWPGPAE

7.79

-3.45

0.30

PFGPWPGPA

9.06

-3.60

0.15
Q01389

KRSKPLPPQ

4.32

-6.20

-2.45

KREAPKPPA

4.57

-6.92

-3.17

RYPQTPSYY

5.96

-2.73

1.02
Q03306

RTKPNVPPL

5.67

-3.16

0.59

ASSEPSSPP

6.17

-4.24

-0.49

KSIPRTKPN

6.64

-4.68

-0.93
P34758

LPLEPLKPT

3.38

-5.55

-1.80

LPPPPPPRA

3.46

-8.72

-4.97

IHSQPNKPN

4.92

-5.38

-1.63
P53933

RRRPPPPPI

3.42

-6.13

-2.38

RTRRRPPPP

3.44

-5.98

-2.23

RRPPPPPIP

4.16

-5.77

-2.02
P32381

LTEPPMNPL

5.58

-5.15

-1.40

LLTEPPMNP

8.41

-3.71

0.04
Q00453

LPHQPPPLP

4.60

-6.70

-2.95

LYAPPYFPH

5.34

-6.03

-2.28

MPSAPIPLP

5.39

-5.71

-1.96
P40021

LNSPPLPPP

4.30

-5.88

-2.13

KNTGPPPPL

5.75

-5.71

-1.96

LDFLPSTPS

6.17

-4.71

-0.96
P36150

IVVNPSSPS

6.65

-4.93

-1.18
Q04439

RHSKKPAPP

4.34

-4.63

-0.88

KKPAPPPPG

4.44

-7.05

-3.30

IPPPPPPPP

4.69

-6.47

-2.72
Q12446

RGPAPPPPP

2.94

-6.95

-3.20

RNNRPVPPP

3.18

-5.68

-1.93

RLPAPPPPP

3.64

-6.69

-2.94
Q01560

QHHQPPEPQ

5.45

-5.43

-1.68

APQEPPAPQ

5.86

-5.20

-1.45

QPPEPQPYY

6.22

-4.54

-0.79
P00950

FDVPPPPID

4.66

-5.32

-1.57

RSFDVPPPP

6.30

-5.03

-1.28

VPPPPIDAS

9.84

-2.96

0.79
P53735

KLVPPPPRT

5.35

-6.25

-2.50

VPPPPRTRS

6.85

-2.87

0.88

LVPPPPRTR

6.98

-3.84

-0.09
P33334

LPPPPPPPP

4.03

-6.62

-2.87

LPPPPPPPS

4.12

-6.67

-2.92

LPPPPPPPG

4.14

-6.62

-2.87
P40523

MHNSPRNPD

5.13

-5.20

-1.45

LAPPPHGPF

6.12

-4.50

-0.75

VGVPPLAPP

6.97

-4.57

-0.82
P40563

RAPPPVPKK

5.11

-4.95

-1.20

ANSEPPTPA

5.72

-5.07

-1.32

KRRAPPPVP

6.43

-5.93

-2.18
Q08989

KGPPPPPPP

4.81

-6.28

-2.53

GPPPPPPPP

6.24

-5.59

-1.84

HPKGPPPPP

6.43

-5.38

-1.63
P37370

MPAPPPPPP

4.17

-6.66

-2.91

IPLAPLPPP

4.70

-6.57

-2.82

LAPLPPPPP

5.27

-6.24

-2.49
P39743

AYSNPLTSP

9.80

-3.15

0.60

YSNPLTSPV

10.29

-3.81

-0.06

SNPLTSPVA

10.59

-3.09

0.66
Q03900

GSHLPNTPS

9.20

-4.06

-0.31

HLPNTPSGA

9.30

-2.38

1.37

PNTPSGAPK

9.49

-3.37

0.38

 


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