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Matrix information:
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ADAN-name: MYO5_1YP5-20.PDB
Scoring matrix: MYO5_1YP5-20_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.17
Foldx random average score for Saccharomyces cerevisiae: 16.693 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1459906
Proteins after disorder filtering: 4602
Total fragments: 89331
Proteins after pattern filtering: 2127
Total fragments: 9251
Proteins after MINT filtering: 43
Total fragments: 490 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
17.17
|
-2.55 |
0.00 |
| Best peptides |
NIFKHGRHY |
0.00
|
-6.59 |
-4.04 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PGQPPLINI |
16.07
|
-5.48 |
-2.93 |
|
PPLPGQPPL |
16.34
|
-6.64 |
-4.09 |
|
LPPLPGQPP |
16.39
|
-7.53 |
-4.98 |
| P39113 |
HRGPRRPQK |
9.49
|
-5.21 |
-2.66 |
|
GPRRPQKNR |
10.39
|
-6.58 |
-4.03 |
|
PPPPHKDHL |
12.25
|
-8.21 |
-5.66 |
| P40073 |
GYPQQQPSH |
13.50
|
-4.21 |
-1.66 |
|
FDGYPQQQP |
16.40
|
-5.81 |
-3.26 |
| P25604 |
LPPKPNTQL |
11.01
|
-8.85 |
-6.30 |
|
KPKSPHLKP |
11.27
|
-6.77 |
-4.22 |
|
PPKPKSPHL |
11.75
|
-8.51 |
-5.96 |
| P25623 |
EPASPSISL |
13.95
|
-5.76 |
-3.21 |
|
PPLPPHATP |
14.07
|
-7.88 |
-5.33 |
|
PPLQPQSKT |
14.35
|
-5.61 |
-3.06 |
| Q05933 |
LPGTPGFPL |
12.36
|
-6.55 |
-4.00 |
|
TPGFPLNNV |
12.54
|
-6.68 |
-4.13 |
|
FRGPAYPSN |
12.64
|
-4.20 |
-1.65 |
| P53094 |
FPQSPIRAY |
11.40
|
-7.25 |
-4.70 |
|
TREPNEPPP |
14.21
|
-7.33 |
-4.78 |
|
VPLPPQTRE |
14.33
|
-6.12 |
-3.57 |
| Q12451 |
AAPKHAPPP |
14.45
|
-6.30 |
-3.75 |
|
HAPPPVPNE |
16.59
|
-4.24 |
-1.69 |
|
PPVPNETDN |
16.61
|
-3.14 |
-0.59 |
| P15891 |
RRATPEKKP |
9.38
|
-8.14 |
-5.59 |
|
PPPPRRATP |
11.71
|
-8.29 |
-5.74 |
|
ISPKPFSKP |
12.05
|
-6.41 |
-3.86 |
| P48562 |
NPYRPHHNM |
8.10
|
-8.40 |
-5.85 |
|
NGQFPRGPM |
11.45
|
-7.14 |
-4.59 |
|
PLNPYRPHH |
12.31
|
-6.55 |
-4.00 |
| P40341 |
PPKPPLNDP |
15.14
|
-6.96 |
-4.41 |
|
PPPPPKPPL |
15.50
|
-7.81 |
-5.26 |
| Q08912 |
YTPSWGPSP |
11.47
|
-6.52 |
-3.97 |
|
PPPPPDEKD |
13.91
|
-5.50 |
-2.95 |
|
GDHPKGPPP |
14.52
|
-6.45 |
-3.90 |
| P17555 |
RPKKPSTLK |
9.96
|
-6.93 |
-4.38 |
|
SGPPPRPKK |
13.07
|
-6.17 |
-3.62 |
|
PPRPKKPST |
14.49
|
-6.01 |
-3.46 |
| Q12342 |
LETPSTPSD |
15.26
|
-4.14 |
-1.59 |
| P47068 |
HPVPSAPSA |
12.58
|
-5.96 |
-3.41 |
|
HPMPNTAPP |
12.92
|
-6.57 |
-4.02 |
|
YHPMPNTAP |
13.12
|
-7.29 |
-4.74 |
| P38822 |
RGPAPEVPP |
15.47
|
-6.11 |
-3.56 |
| P04050 |
NYSPTSPSY |
9.71
|
-5.15 |
-2.60 |
|
PPPPVRPSI |
10.08
|
-7.85 |
-5.30 |
|
SPTSPGYSP |
10.78
|
-5.79 |
-3.24 |
| P40450 |
PKLFPRLSS |
11.92
|
-4.67 |
-2.12 |
|
PPLPESLSM |
13.41
|
-7.05 |
-4.50 |
|
PPLPNGLLS |
13.80
|
-5.14 |
-2.59 |
| P40453 |
VPEPPSWKP |
11.55
|
-8.07 |
-5.52 |
|
PDLPIRLRK |
13.86
|
-5.25 |
-2.70 |
|
MPTTPEIPP |
13.91
|
-7.87 |
-5.32 |
| Q12168 |
PPLPPRANV |
12.10
|
-8.19 |
-5.64 |
|
NDDPYFPQF |
12.57
|
-5.04 |
-2.49 |
|
DPYFPQFRS |
13.18
|
-6.02 |
-3.47 |
| P41832 |
PPPPPLPSV |
13.22
|
-8.62 |
-6.07 |
|
PPPPPMALF |
13.37
|
-7.30 |
-4.75 |
| P36006 |
MGQPKDPKF |
12.39
|
-6.14 |
-3.59 |
|
PPPMGQPKD |
13.01
|
-6.19 |
-3.64 |
|
KPKNPGGLS |
13.29
|
-5.35 |
-2.80 |
| P38753 |
SPPVPGPAL |
12.18
|
-7.03 |
-4.48 |
|
NLPIQHPTN |
13.74
|
-7.34 |
-4.79 |
|
HISPPVPGP |
14.30
|
-6.35 |
-3.80 |
| P38237 |
IPSKPENTV |
13.74
|
-7.05 |
-4.50 |
|
NFQIPSKPE |
14.99
|
-3.39 |
-0.84 |
|
VPPPNVPKK |
15.13
|
-6.65 |
-4.10 |
| P34245 |
YSTPFGPWP |
10.86
|
-6.26 |
-3.71 |
|
FGPWPGPAE |
14.72
|
-4.02 |
-1.47 |
|
TPFGPWPGP |
14.85
|
-5.67 |
-3.12 |
| Q01389 |
RPVPPDSSY |
8.78
|
-9.35 |
-6.80 |
|
RRYPQTPSY |
8.78
|
-7.87 |
-5.32 |
|
NIPSPSSSP |
9.17
|
-5.84 |
-3.29 |
| Q03306 |
NKSIPRTKP |
7.96
|
-7.99 |
-5.44 |
|
SIPRTKPNV |
12.62
|
-5.99 |
-3.44 |
|
GYRQPTPSP |
13.02
|
-6.18 |
-3.63 |
| P34758 |
NQQQPQHLP |
11.03
|
-6.28 |
-3.73 |
|
HSQPNKPNY |
11.25
|
-6.50 |
-3.95 |
|
PPPPPRAQQ |
12.38
|
-7.70 |
-5.15 |
| P53933 |
PPLPNRQLP |
11.21
|
-7.54 |
-4.99 |
|
PPIPSTQKP |
13.37
|
-6.57 |
-4.02 |
|
VAPPPLPNR |
13.61
|
-6.55 |
-4.00 |
| Q00453 |
PPYFPHPMP |
10.49
|
-8.73 |
-6.18 |
|
YAPPYFPHP |
11.96
|
-6.35 |
-3.80 |
|
MPSAPIPLP |
12.67
|
-7.27 |
-4.72 |
| P40021 |
PLPPPARSQ |
12.90
|
-4.85 |
-2.30 |
|
PPLFPSSST |
13.39
|
-5.74 |
-3.19 |
|
LPPPLFPSS |
13.83
|
-6.58 |
-4.03 |
| Q04439 |
APPPPGMQN |
11.87
|
-6.27 |
-3.72 |
|
PPPPPSSKP |
12.10
|
-8.18 |
-5.63 |
|
HSKKPAPPP |
12.77
|
-7.20 |
-4.65 |
| Q12446 |
PPPPPRASR |
9.45
|
-7.65 |
-5.10 |
|
PPPPPRRGP |
9.67
|
-8.38 |
-5.83 |
|
PPPRRGPAP |
9.68
|
-8.29 |
-5.74 |
| Q01560 |
PPPPPGEHM |
9.92
|
-9.63 |
-7.08 |
|
QPPEPQPYY |
12.32
|
-7.25 |
-4.70 |
|
HHQPPEPQP |
13.13
|
-5.30 |
-2.75 |
| P00950 |
PPPPIDASS |
14.96
|
-5.35 |
-2.80 |
| P53735 |
PPPPRTRSP |
9.95
|
-5.97 |
-3.42 |
|
VPPPPRTRS |
12.92
|
-7.01 |
-4.46 |
| P33334 |
NAIPGGPKF |
8.62
|
-6.10 |
-3.55 |
|
NNAIPGGPK |
13.24
|
-4.74 |
-2.19 |
|
GGPKFEPLY |
13.32
|
-5.98 |
-3.43 |
| P40523 |
VPVPVGVPP |
12.86
|
-7.24 |
-4.69 |
|
APPPHGPFS |
13.03
|
-4.45 |
-1.90 |
|
LGAPPGTVP |
14.51
|
-6.44 |
-3.89 |
| P40563 |
NSQPQGPSD |
10.42
|
-3.18 |
-0.63 |
|
GMVNPGQLP |
12.91
|
-5.47 |
-2.92 |
|
PSERPKRRA |
14.38
|
-5.42 |
-2.87 |
| Q08989 |
PPPPDEKGR |
13.75
|
-5.74 |
-3.19 |
|
GDHPKGPPP |
14.52
|
-6.45 |
-3.90 |
|
PPPPPDEKG |
15.02
|
-5.76 |
-3.21 |
| P37370 |
RPHMPSVRP |
8.72
|
-9.62 |
-7.07 |
|
RPSPISPSI |
9.49
|
-7.61 |
-5.06 |
|
KVPQNRPHM |
9.51
|
-8.72 |
-6.17 |
| P39743 |
NATIPEDNP |
12.11
|
-5.45 |
-2.90 |
|
AYSNPLTSP |
14.37
|
-6.25 |
-3.70 |
| Q03900 |
NTPSGAPKL |
13.25
|
-4.55 |
-2.00 |
|
LPNTPSGAP |
13.40
|
-7.85 |
-5.30 |
|
