ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1YP5-2.PDB
Scoring matrix: MYO5_1YP5-2_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 14.56
Foldx random average score for Saccharomyces cerevisiae: 15.127

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1595658
Proteins after disorder filtering: 4569
 Total fragments: 118516
Proteins after pattern filtering: 2323
 Total fragments: 23344
Proteins after MINT filtering: 45
 Total fragments: 1577

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

14.56

-3.99

0.00
Best peptides

SPLYMFMDRF

0.00

-6.75

-2.76
         
Interactors      
P53145

PLPGQPPLIN

8.23

-7.25

-3.26

PPLPGQPPLI

9.52

-8.25

-4.26

NEPLLPPLPG

9.54

-4.93

-0.94
P39113

PLGAPPPPPH

6.76

-9.29

-5.30

SPLGAPPPPP

7.00

-7.95

-3.96

GPRRPQKNRY

8.27

-6.71

-2.72
P40073

QFDGYPQQQP

8.86

-5.79

-1.80

GYPQQQPSHT

12.96

-3.20

0.79

DGYPQQQPSH

13.40

-2.55

1.44
P25604

SPHLKPPLPP

6.88

-8.90

-4.91

PLPPPPPPQP

7.23

-8.98

-4.99

PHLKPPLPPP

8.16

-9.08

-5.09
P25623

QPPLQPQSKT

7.10

-7.39

-3.40

PPLPPHATPK

8.78

-7.54

-3.55

PPLQPQSKTK

9.51

-5.10

-1.11
Q05933

PGTPGFPLNN

10.34

-4.98

-0.99

GPAYPSNSDY

11.22

-3.94

0.05

TKFRGPAYPS

11.57

-4.22

-0.23
P53094

NVPLPPQTRE

7.82

-6.19

-2.20

EPNEPPPPCP

8.10

-8.85

-4.86

AFPQSPIRAY

8.39

-5.83

-1.84
Q12451

APKHAPPPVP

6.46

-9.97

-5.98

QPHLLPWLPP

7.58

-7.57

-3.58

PKHAPPPVPN

8.44

-6.30

-2.31
P15891

SAAPPPPPRR

7.03

-6.11

-2.12

SSAAPPPPPR

8.11

-6.45

-2.46

APPPPPRRAT

8.34

-5.74

-1.75
P48562

PPISAPRAPY

6.22

-7.26

-3.27

QFPRGPMHPN

7.07

-6.12

-2.13

SPLNPYRPHH

7.36

-6.46

-2.47
P40341

PPPPPPPPPK

5.83

-9.68

-5.69

PPPPPPPPKP

6.29

-10.04

-6.05

PPPPPPPKPP

6.90

-9.74

-5.75
Q08912

PPPPPPPDEK

5.51

-9.50

-5.51

PKGPPPPPPP

7.76

-8.10

-4.11

HPKGPPPPPP

7.89

-8.61

-4.62
P17555

SKSGPPPRPK

6.96

-6.62

-2.63

APAPPPPPPA

7.28

-7.68

-3.69

APPPPPPAPP

7.43

-8.45

-4.46
Q12342

APPPPPPPPP

7.01

-9.63

-5.64

AKAPPPPPPP

7.88

-5.89

-1.90

KAPPPPPPPP

10.83

-7.26

-3.27
P47068

DPSSNPFFRK

6.99

-5.27

-1.28

PLPRAPPVPP

7.84

-8.96

-4.97

APSIPPVPPT

7.89

-6.67

-2.68
P38822

APEVPPPRRS

7.04

-6.85

-2.86

PAPEVPPPRR

7.54

-7.40

-3.41

GPAPEVPPPR

10.97

-6.16

-2.17
P04050

SPGYSPGSPA

6.82

-7.14

-3.15

SPSYSPTSPN

6.89

-6.58

-2.59

SPSYSPTSPA

7.38

-8.26

-4.27
P40450

PPPPPPPPPP

6.77

-10.46

-6.47

PPPPPPPPPL

7.27

-8.29

-4.30

PPPPPPPLPE

7.43

-8.29

-4.30
P40453

PPPPPPVSMP

7.61

-9.68

-5.69

TPEIPPPLPP

7.97

-8.02

-4.03

PPSWKPPDLP

8.29

-9.60

-5.61
Q12168

PPPLPPRANV

7.01

-6.93

-2.94

DNDDPYFPQF

7.95

-3.63

0.36

NKVQHPVPKP

8.75

-6.79

-2.80
P41832

PPPPPPPPPM

5.93

-8.79

-4.80

PPPPPPMALF

6.40

-9.15

-5.16

SPAPPPPPPP

6.71

-8.29

-4.30
P36006

PPPPPPMGQP

6.37

-10.55

-6.56

PPMGQPKDPK

7.19

-8.36

-4.37

NIPIPPPPPP

7.23

-7.59

-3.60
P38753

TPVMPPQRQS

8.39

-7.10

-3.11

PVMPPQRQSY

9.26

-4.33

-0.34

NNTPVMPPQR

9.86

-5.39

-1.40
P38237

DLNDPFVPPP

9.25

-6.31

-2.32

DPFVPPPNVP

9.31

-7.79

-3.80

PFVPPPNVPK

9.87

-5.76

-1.77
P34245

STPFGPWPGP

10.14

-6.61

-2.62

PFGPWPGPAE

11.28

-5.15

-1.16

AYSTPFGPWP

11.31

-5.46

-1.47
Q01389

SPSYPSIFRR

4.91

-5.36

-1.37

SPSSSPPPIP

7.36

-8.14

-4.15

PASPSYPSIF

8.39

-6.60

-2.61
Q03306

SPPLPQMEFP

7.06

-7.67

-3.68

PSSPPPISRK

7.34

-4.81

-0.82

PSPPLPQMEF

8.27

-4.18

-0.19
P34758

QPQHLPPPPP

5.66

-10.57

-6.58

QHLPPPPPPR

6.84

-6.27

-2.28

HLPPPPPPRA

7.82

-5.77

-1.78
P53933

PPPPIPSTQK

8.42

-7.85

-3.86

TRRRPPPPPI

9.20

-5.86

-1.87

PPPLPNRQLP

9.59

-7.94

-3.95
P32381

LLTEPPMNPL

9.56

-7.09

-3.10

ILLTEPPMNP

14.72

-5.39

-1.40
Q00453

APPYFPHPMP

6.06

-8.70

-4.71

PPYFPHPMPS

7.19

-8.85

-4.86

PLPHQPPPLP

7.60

-9.23

-5.24
P40021

SPPLPPPARS

6.27

-7.14

-3.15

PPPPLPPPLF

6.84

-8.84

-4.85

PPPLPPPLFP

7.63

-8.61

-4.62
P36150

PIVVNPSSPS

10.52

-6.31

-2.32

NPIVVNPSSP

11.54

-6.85

-2.86
Q04439

PPSSKPKEPM

7.01

-8.62

-4.63

SKPKEPMFEA

7.25

-6.83

-2.84

PPPPPPPPPS

7.32

-8.30

-4.31
Q12446

APAPPPPPQM

6.04

-8.37

-4.38

LPAPPPPPRR

6.82

-8.96

-4.97

SNPFPFPIPE

6.87

-7.84

-3.85
Q01560

QPYYPPPPPG

4.85

-10.53

-6.54

PQPYYPPPPP

6.22

-7.57

-3.58

EPQPYYPPPP

7.07

-9.12

-5.13
P00950

SFDVPPPPID

8.84

-6.15

-2.16

DVPPPPIDAS

10.00

-5.09

-1.10

PPPPIDASSP

13.52

-6.75

-2.76
P53735

APKLVPPPPR

6.01

-8.29

-4.30

PKLVPPPPRT

7.11

-5.92

-1.93

LVPPPPRTRS

9.31

-5.83

-1.84
P33334

PPPPPPPSNF

6.35

-7.79

-3.80

ALPPPPPPPP

7.56

-8.21

-4.22

PPPPPPPPGY

7.60

-8.13

-4.14
P40523

PPPHGPFSTS

7.77

-6.40

-2.41

PLAPPPHGPF

8.38

-6.39

-2.40

PPLAPPPHGP

8.87

-7.51

-3.52
P40563

PKRRAPPPVP

8.18

-9.11

-5.12

APPPVPKKPS

9.20

-6.52

-2.53

NPGQLPPSLE

9.23

-8.42

-4.43
Q08989

PPPPPPPDEK

5.51

-9.50

-5.51

PKGPPPPPPP

7.76

-8.10

-4.11

HPKGPPPPPP

7.89

-8.61

-4.62
P37370

PPTLAPPLPN

6.75

-8.57

-4.58

NPTKSPPPPP

6.92

-9.40

-5.41

APAPPPPPPP

6.98

-9.07

-5.08
P39743

PNATIPEDNP

10.20

-6.15

-2.16

PAYSNPLTSP

13.02

-6.23

-2.24
Q03900

TPSGAPKLKN

9.18

-6.27

-2.28

NTPSGAPKLK

11.51

-5.28

-1.29

LPNTPSGAPK

12.38

-5.28

-1.29

 


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