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Matrix information:
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ADAN-name: MYO5_1YP5-11.PDB
Scoring matrix: MYO5_1YP5-11_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.67
Foldx random average score for Saccharomyces cerevisiae: 9.877 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3221900
Proteins after random average filtering: 7179
Total fragments: 1350433
Proteins after disorder filtering: 4551
Total fragments: 72505
Proteins after pattern filtering: 2240
Total fragments: 12225
Proteins after MINT filtering: 44
Total fragments: 970 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
12.67
|
-0.20 |
0.00 |
| Best peptides |
YRPLPPR |
0.00
|
-7.22 |
-7.01 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
LPPLPGQ |
4.84
|
-7.68 |
-7.47 |
|
EPLLPPL |
6.07
|
-6.36 |
-6.16 |
|
NEPLLPP |
6.78
|
-5.47 |
-5.26 |
| P39113 |
RGPRRPQ |
6.44
|
-4.97 |
-4.76 |
|
GPRRPQK |
7.22
|
-5.27 |
-5.06 |
|
APPPPPH |
7.34
|
-5.21 |
-5.00 |
| P40073 |
YPQQQPS |
7.12
|
-4.89 |
-4.68 |
|
PQQQPSH |
8.38
|
-3.88 |
-3.67 |
|
GYPQQQP |
9.75
|
-2.10 |
-1.90 |
| P25604 |
KPPLPPP |
4.70
|
-7.83 |
-7.63 |
|
TPPLPPK |
5.40
|
-6.23 |
-6.03 |
|
APSLPPK |
5.61
|
-6.80 |
-6.59 |
| P25623 |
TPPLPPH |
5.52
|
-5.64 |
-5.43 |
|
QPPLQPQ |
6.76
|
-5.05 |
-4.84 |
|
PPSTPQQ |
7.39
|
-5.59 |
-5.38 |
| Q05933 |
GPAYPSN |
6.35
|
-5.24 |
-5.04 |
|
LPGTPGF |
6.49
|
-6.14 |
-5.93 |
|
FRGPAYP |
7.30
|
-3.09 |
-2.88 |
| P53094 |
YPLKLPP |
4.43
|
-8.08 |
-7.88 |
|
FPQSPIR |
5.55
|
-5.18 |
-4.97 |
|
NVPLPPQ |
6.14
|
-5.25 |
-5.04 |
| Q12451 |
QPHLLPW |
6.05
|
-5.61 |
-5.41 |
|
LPWLPPT |
6.22
|
-6.91 |
-6.71 |
|
PPPVPNE |
7.62
|
-5.61 |
-5.41 |
| P15891 |
QPPLPSR |
4.13
|
-6.73 |
-6.53 |
|
APPPPPR |
5.67
|
-5.88 |
-5.67 |
|
PPPPPRR |
5.92
|
-5.83 |
-5.63 |
| P48562 |
RGPMHPN |
5.67
|
-4.59 |
-4.38 |
|
NPYRPHH |
6.64
|
-5.07 |
-4.87 |
|
SPLNPYR |
6.78
|
-4.73 |
-4.53 |
| P40341 |
PPPKPPL |
6.29
|
-7.05 |
-6.84 |
|
NIPPPPP |
6.34
|
-4.59 |
-4.38 |
|
IPPPPPP |
6.54
|
-5.55 |
-5.34 |
| Q08912 |
PPPPPPP |
7.25
|
-6.19 |
-5.99 |
|
YTPSWGP |
7.63
|
-3.37 |
-3.17 |
|
GPPPPPP |
7.98
|
-4.95 |
-4.75 |
| P17555 |
RPKKPST |
5.86
|
-7.67 |
-7.46 |
|
PPPRPKK |
6.41
|
-6.37 |
-6.17 |
|
PRPKKPS |
7.08
|
-3.93 |
-3.73 |
| Q12342 |
PPPPPPP |
7.25
|
-6.19 |
-5.99 |
|
APPPPPP |
7.29
|
-6.00 |
-5.79 |
|
KAPPPPP |
7.98
|
-4.83 |
-4.63 |
| P47068 |
PPGIPTN |
6.11
|
-5.59 |
-5.38 |
|
APSIPPV |
6.57
|
-5.74 |
-5.54 |
|
IPPVPPT |
6.57
|
-5.46 |
-5.25 |
| P38822 |
APEVPPP |
6.43
|
-5.95 |
-5.75 |
|
PEVPPPR |
7.30
|
-4.31 |
-4.10 |
| P04050 |
VPPPPVR |
6.24
|
-4.21 |
-4.00 |
|
CLPVPPP |
6.74
|
-5.72 |
-5.51 |
|
PPVRPSI |
6.96
|
-5.82 |
-5.62 |
| P40450 |
SPKLFPR |
4.94
|
-5.50 |
-5.29 |
|
LPQLPPP |
5.74
|
-7.42 |
-7.21 |
|
PPPLPDL |
5.79
|
-6.71 |
-6.50 |
| P40453 |
PPDLPIR |
4.60
|
-6.76 |
-6.55 |
|
PPPLPPK |
5.14
|
-7.69 |
-7.49 |
|
RPPPPPP |
5.29
|
-6.72 |
-6.51 |
| Q12168 |
PPPLPPR |
3.59
|
-7.84 |
-7.63 |
|
PPPVPNR |
4.90
|
-6.60 |
-6.39 |
|
DPYFPQF |
7.27
|
-5.50 |
-5.29 |
| P41832 |
PPPLPSV |
6.26
|
-6.57 |
-6.37 |
|
PPPVPAK |
6.51
|
-6.49 |
-6.29 |
|
IPPAPPM |
6.74
|
-4.82 |
-4.62 |
| P36006 |
NIPIPPP |
4.33
|
-5.59 |
-5.38 |
|
IPPPPPP |
6.54
|
-5.55 |
-5.34 |
|
PIPPPPP |
6.56
|
-5.30 |
-5.09 |
| P38753 |
YPSNLPI |
5.73
|
-6.26 |
-6.05 |
|
TPVMPPQ |
5.80
|
-6.10 |
-5.89 |
|
SPPVPGP |
6.61
|
-5.20 |
-5.00 |
| P38237 |
IPSKPEN |
6.55
|
-5.49 |
-5.29 |
|
DPFVPPP |
6.98
|
-5.34 |
-5.13 |
|
PPNVPKK |
7.15
|
-6.25 |
-6.04 |
| P34245 |
FGPWPGP |
7.09
|
-4.76 |
-4.55 |
|
YSTPFGP |
7.34
|
-4.01 |
-3.80 |
|
TPFGPWP |
9.19
|
-3.26 |
-3.05 |
| Q01389 |
YPQTPSY |
4.46
|
-6.40 |
-6.20 |
|
SKPLPPQ |
5.83
|
-5.36 |
-5.16 |
|
EPSTPSR |
6.12
|
-5.42 |
-5.21 |
| Q03306 |
SPPLPQM |
5.84
|
-6.09 |
-5.88 |
|
RQPTPSP |
6.09
|
-6.42 |
-6.21 |
|
KPNVPPL |
6.47
|
-6.54 |
-6.34 |
| P34758 |
PPPPPPR |
5.62
|
-6.30 |
-6.09 |
|
VPTQPSY |
6.49
|
-3.94 |
-3.73 |
|
PQHLPPP |
6.65
|
-5.60 |
-5.39 |
| P53933 |
PPPLPNR |
4.06
|
-7.28 |
-7.08 |
|
RRPPPPP |
4.35
|
-6.23 |
-6.03 |
|
RRRPPPP |
4.63
|
-5.37 |
-5.17 |
| P32381 |
EPPMNPL |
7.38
|
-4.63 |
-4.42 |
| Q00453 |
PIPLPHQ |
4.69
|
-6.23 |
-6.03 |
|
PPPLPIY |
5.06
|
-6.16 |
-5.96 |
|
YFPHPMP |
5.14
|
-5.72 |
-5.51 |
| P40021 |
PPPLPPP |
5.22
|
-7.68 |
-7.47 |
|
SPPLPPP |
5.65
|
-6.49 |
-6.29 |
|
PPPLFPS |
6.87
|
-5.80 |
-5.59 |
| Q04439 |
NIPTPPQ |
5.77
|
-5.15 |
-4.95 |
|
NIPPPPP |
6.34
|
-4.59 |
-4.38 |
|
KPKEPMF |
6.47
|
-5.19 |
-4.99 |
| Q12446 |
LPQLPNR |
4.59
|
-7.26 |
-7.05 |
|
FAPLPDP |
4.87
|
-5.76 |
-5.55 |
|
NRPVPPP |
4.89
|
-4.97 |
-4.76 |
| Q01560 |
YPPPPPG |
5.21
|
-7.71 |
-7.50 |
|
YYPPPPP |
5.42
|
-6.19 |
-5.99 |
|
QPYYPPP |
6.18
|
-6.36 |
-6.16 |
| P00950 |
FDVPPPP |
7.18
|
-4.30 |
-4.09 |
|
VPPPPID |
9.33
|
-3.60 |
-3.40 |
|
DVPPPPI |
9.49
|
-3.89 |
-3.69 |
| P53735 |
LVPPPPR |
6.79
|
-5.32 |
-5.12 |
|
PKLVPPP |
6.92
|
-5.37 |
-5.17 |
|
PPPPRTR |
7.21
|
-4.78 |
-4.58 |
| P33334 |
FLPPPPP |
6.11
|
-5.59 |
-5.38 |
|
MPTRFPP |
6.29
|
-6.10 |
-5.89 |
|
PPPPPGF |
6.44
|
-5.76 |
-5.55 |
| P40523 |
ITPLPTP |
6.92
|
-4.07 |
-3.87 |
|
VPPLAPP |
7.06
|
-4.26 |
-4.05 |
|
PPLAPPP |
7.96
|
-5.58 |
-5.38 |
| P40563 |
TPNVPTR |
6.04
|
-4.49 |
-4.29 |
|
TPKVPER |
6.25
|
-4.91 |
-4.71 |
|
PPPVPKK |
6.47
|
-6.46 |
-6.25 |
| Q08989 |
PPPPPPP |
7.25
|
-6.19 |
-5.99 |
|
GPPPPPP |
7.98
|
-4.95 |
-4.75 |
|
PKGPPPP |
8.29
|
-4.06 |
-3.85 |
| P37370 |
RPHMPSV |
4.89
|
-6.85 |
-6.64 |
|
APPLPTF |
4.99
|
-5.90 |
-5.70 |
|
APPIPGM |
5.32
|
-6.23 |
-6.03 |
| P39743 |
TIPEDNP |
9.59
|
-1.34 |
-1.14 |
| Q03900 |
LPNTPSG |
8.19
|
-5.86 |
-5.66 |
|
