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Matrix information:
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ADAN-name: MYO5_1YP5-10.PDB
Scoring matrix: MYO5_1YP5-10_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.98
Foldx random average score for Saccharomyces cerevisiae: 12.809 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1591284
Proteins after disorder filtering: 4810
Total fragments: 107655
Proteins after pattern filtering: 2286
Total fragments: 13534
Proteins after MINT filtering: 45
Total fragments: 975 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
13.98
|
3.94 |
0.00 |
| Best peptides |
RKRKGWWR |
0.00
|
-5.66 |
-9.60 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
EPLLPPLP |
9.11
|
-2.79 |
-6.73 |
|
LPPLPGQP |
9.29
|
-4.09 |
-8.03 |
|
PPLPGQPP |
9.48
|
-2.86 |
-6.80 |
| P39113 |
MSPLGAPP |
8.90
|
-2.94 |
-6.88 |
|
APPPPPHK |
9.49
|
-0.88 |
-4.82 |
|
THPEGPNC |
10.41
|
-1.59 |
-5.53 |
| P40073 |
YPQQQPSH |
10.84
|
-0.66 |
-4.60 |
|
PQQQPSHT |
11.58
|
-1.88 |
-5.82 |
| P25604 |
PKPKSPHL |
7.63
|
-2.65 |
-6.59 |
|
LPPKPKSP |
9.23
|
-4.45 |
-8.39 |
|
KPPLPPPP |
9.49
|
-4.72 |
-8.66 |
| P25623 |
TPPLPPHA |
8.91
|
-3.81 |
-7.75 |
|
TKPLPVEP |
10.31
|
-1.16 |
-5.10 |
|
PKTVPISI |
10.53
|
-3.47 |
-7.41 |
| Q05933 |
FRGPAYPS |
10.24
|
-2.03 |
-5.97 |
|
FTLPGTPG |
10.31
|
-0.52 |
-4.46 |
|
PVDPNTDR |
10.63
|
2.39 |
-1.55 |
| P53094 |
FPQSPIRA |
8.73
|
-3.13 |
-7.07 |
|
AFPQSPIR |
9.33
|
-1.83 |
-5.77 |
|
YPLKLPPL |
9.34
|
-2.12 |
-6.06 |
| Q12451 |
QPHLLPWL |
9.22
|
-3.08 |
-7.02 |
|
LPWLPPTD |
9.58
|
-2.00 |
-5.94 |
|
PHLLPWLP |
10.40
|
-1.40 |
-5.34 |
| P15891 |
APPPPPRR |
7.82
|
-2.50 |
-6.44 |
|
QPPLPSRN |
8.04
|
-4.62 |
-8.56 |
|
KPEVPEDE |
9.11
|
-3.81 |
-7.75 |
| P48562 |
QFPRGPMH |
6.16
|
-3.88 |
-7.82 |
|
KPPISAPR |
7.08
|
-2.48 |
-6.42 |
|
FPRGPMHP |
8.67
|
-0.92 |
-4.86 |
| P40341 |
PPPKPPLN |
8.83
|
-2.22 |
-6.16 |
|
KPPLNDPS |
9.75
|
-0.95 |
-4.89 |
|
RNIPPPPP |
10.28
|
-4.09 |
-8.03 |
| Q08912 |
TPSWGPSP |
8.99
|
-2.75 |
-6.69 |
|
DHPKGPPP |
9.78
|
-2.99 |
-6.93 |
|
PPPPDEKD |
10.75
|
-0.13 |
-4.07 |
| P17555 |
RPKKPSTL |
7.20
|
-5.08 |
-9.02 |
|
PKKPSTLK |
9.29
|
-1.47 |
-5.41 |
|
KSGPPPRP |
10.07
|
-2.90 |
-6.84 |
| Q12342 |
PPPPPPPP |
11.77
|
-3.58 |
-7.52 |
|
APPPPPPP |
11.93
|
-2.45 |
-6.39 |
|
AKAPPPPP |
11.96
|
-1.22 |
-5.16 |
| P47068 |
YVPPGIPT |
8.44
|
-2.01 |
-5.95 |
|
MPFVDPSS |
8.59
|
0.01 |
-3.93 |
|
YYVPPGIP |
9.15
|
-1.12 |
-5.06 |
| P38822 |
PEVPPPRR |
8.90
|
-2.77 |
-6.71 |
|
APEVPPPR |
9.59
|
-3.35 |
-7.29 |
|
RGPAPEVP |
11.95
|
-2.03 |
-5.97 |
| P04050 |
VPPPPVRP |
9.21
|
-3.84 |
-7.78 |
|
PPVRPSIS |
9.85
|
-1.54 |
-5.48 |
|
VSSPGFSP |
10.12
|
-1.37 |
-5.31 |
| P40450 |
SPKLFPRL |
9.02
|
-1.41 |
-5.35 |
|
PPLPDLFK |
9.57
|
1.02 |
-2.92 |
|
PPPLPDLF |
9.89
|
-4.84 |
-8.78 |
| P40453 |
CPRCGPTA |
8.21
|
-2.29 |
-6.23 |
|
PPDLPIRL |
8.26
|
-4.32 |
-8.26 |
|
VPEPPSWK |
8.67
|
-1.35 |
-5.29 |
| Q12168 |
PPPLPPRA |
8.67
|
-4.13 |
-8.07 |
|
PPPVPNRP |
9.38
|
-5.23 |
-9.17 |
|
PNRPGGTT |
9.90
|
-0.48 |
-4.42 |
| P41832 |
PPAPPMMP |
9.48
|
-2.90 |
-6.84 |
|
IPPAPPMM |
9.75
|
-3.25 |
-7.19 |
|
PPLPSVLS |
9.96
|
-1.53 |
-5.47 |
| P36006 |
PKNPGGLS |
8.13
|
-3.30 |
-7.24 |
|
PPPMGQPK |
8.14
|
-4.15 |
-8.09 |
|
KKPKNPGG |
9.11
|
-1.25 |
-5.19 |
| P38753 |
TPVMPPQR |
7.44
|
-3.99 |
-7.93 |
|
PPVPGPAL |
8.82
|
-2.86 |
-6.80 |
|
YPSNLPIQ |
9.75
|
-0.26 |
-4.20 |
| P38237 |
IPSKPENT |
8.93
|
-4.03 |
-7.97 |
|
FQIPSKPE |
10.19
|
-0.51 |
-4.45 |
|
PPNVPKKD |
10.73
|
-3.96 |
-7.90 |
| P34245 |
GPWPGPAE |
8.76
|
-2.46 |
-6.40 |
|
STPFGPWP |
9.34
|
-1.86 |
-5.80 |
|
PFGPWPGP |
12.04
|
3.30 |
-0.64 |
| Q01389 |
RPVPPDSS |
9.22
|
-3.98 |
-7.92 |
|
IPSPSSSP |
9.42
|
-1.50 |
-5.44 |
|
KRSKPLPP |
9.52
|
-1.08 |
-5.02 |
| Q03306 |
KPNVPPLQ |
8.51
|
-3.67 |
-7.61 |
|
PPKVPVIN |
9.48
|
-3.27 |
-7.21 |
|
SPPLPQME |
9.67
|
-4.26 |
-8.20 |
| P34758 |
LPPPPPPR |
9.60
|
-3.14 |
-7.08 |
|
PPPPPPRA |
9.61
|
-3.93 |
-7.87 |
|
QPLKPTAT |
10.32
|
-3.08 |
-7.02 |
| P53933 |
RPPPPPIP |
7.55
|
-4.93 |
-8.87 |
|
YPGNPTSR |
8.63
|
-2.84 |
-6.78 |
|
PPPLPNRQ |
9.11
|
-5.15 |
-9.09 |
| P32381 |
LTEPPMNP |
11.94
|
-0.86 |
-4.80 |
| Q00453 |
PPPLPIYS |
10.12
|
-3.89 |
-7.83 |
|
APPYFPHP |
10.52
|
0.88 |
-3.06 |
|
APIPLPHQ |
10.54
|
0.94 |
-3.00 |
| P40021 |
PPLPPPAR |
9.79
|
-3.20 |
-7.14 |
|
PPLPPPLF |
10.23
|
-2.87 |
-6.81 |
|
LDFLPSTP |
10.25
|
-2.28 |
-6.22 |
| P36150 |
IVVNPSSP |
12.32
|
-2.27 |
-6.21 |
| Q04439 |
PPPPGMQN |
7.58
|
-3.87 |
-7.81 |
|
IPTPPQNR |
8.60
|
-2.01 |
-5.95 |
|
KPKEPMFE |
9.20
|
-2.63 |
-6.57 |
| Q12446 |
PPRRGPAP |
7.65
|
-4.44 |
-8.38 |
|
APPPPPRR |
7.82
|
-2.50 |
-6.44 |
|
VPPPPPMR |
7.85
|
-3.51 |
-7.45 |
| Q01560 |
PPPPGEHM |
7.47
|
-3.42 |
-7.36 |
|
YPPPPPGE |
9.64
|
-2.60 |
-6.54 |
|
PPSNAPIY |
10.08
|
-1.20 |
-5.14 |
| P00950 |
VPPPPIDA |
10.96
|
-2.44 |
-6.38 |
|
FDVPPPPI |
11.25
|
-2.25 |
-6.19 |
|
SFDVPPPP |
12.52
|
-2.04 |
-5.98 |
| P53735 |
VPPPPRTR |
9.29
|
-2.58 |
-6.52 |
|
KLVPPPPR |
9.53
|
-2.13 |
-6.07 |
|
LVPPPPRT |
10.52
|
-3.51 |
-7.45 |
| P33334 |
PPPPGLDE |
8.25
|
-3.28 |
-7.22 |
|
PPPPGFEE |
8.32
|
-2.92 |
-6.86 |
|
PPPPGYEI |
8.89
|
-2.88 |
-6.82 |
| P40523 |
PPPHGPFS |
8.73
|
-3.31 |
-7.25 |
|
VPPLAPPP |
9.55
|
-3.66 |
-7.60 |
|
PVPVGVPP |
10.22
|
-3.14 |
-7.08 |
| P40563 |
MVNPGQLP |
8.43
|
-3.50 |
-7.44 |
|
TPKVPERP |
8.62
|
-3.87 |
-7.81 |
|
RRAPPPVP |
8.76
|
-5.19 |
-9.13 |
| Q08989 |
DHPKGPPP |
9.78
|
-2.99 |
-6.93 |
|
PPPPDEKG |
10.82
|
0.32 |
-3.62 |
|
PPPPPPDE |
10.89
|
-1.66 |
-5.60 |
| P37370 |
RPHMPSVR |
5.40
|
-6.78 |
-10.72 |
|
PPIPGAVP |
7.88
|
-3.48 |
-7.42 |
|
PPPPGAFS |
8.44
|
-3.11 |
-7.05 |
| P39743 |
NPLTSPVA |
11.53
|
-0.53 |
-4.47 |
|
YSNPLTSP |
12.44
|
0.47 |
-3.47 |
| Q03900 |
TPSGAPKL |
11.27
|
-2.19 |
-6.13 |
|
PNTPSGAP |
12.29
|
0.03 |
-3.91 |
|
NTPSGAPK |
12.69
|
0.71 |
-3.23 |
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