ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1VA7-26.PDB
Scoring matrix: MYO5_1VA7-26_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.4
Foldx random average score for Saccharomyces cerevisiae: 13.766

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1625851
Proteins after disorder filtering: 4592
 Total fragments: 82243
Proteins after pattern filtering: 2235
 Total fragments: 12591
Proteins after MINT filtering: 44
 Total fragments: 690

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.40

1.99

0.00
Best peptides

DDMKRMPPR

0.00

-3.32

-5.31
         
Interactors      
P53145

EPLLPPLPG

9.86

-4.60

-6.59

NEPLLPPLP

9.93

-4.61

-6.60

PLPGQPPLI

11.74

-2.59

-4.58
P39113

MSPLGAPPP

10.13

-4.32

-6.31

SPLGAPPPP

10.13

-1.89

-3.88

GPRRPQKNR

10.14

-3.36

-5.35
P40073

GYPQQQPSH

11.25

-3.88

-5.87

YPQQQPSHT

13.26

-0.16

-2.15
P25604

PKPKSPHLK

6.50

-3.33

-5.32

TPPLPPKPK

6.81

-3.43

-5.42

KPPLPPPPP

8.61

-4.03

-6.02
P25623

QPPLQPQSK

8.46

-2.51

-4.50

NLPKTVPIS

9.50

-3.92

-5.91

TKPLPVEPA

9.56

-2.90

-4.89
Q05933

FPVDPNTDR

9.55

-1.43

-3.42

TFPVDPNTD

12.10

-0.71

-2.70

RGPAYPSNS

12.31

-1.28

-3.27
P53094

DDEDPVSPK

6.23

-2.39

-4.38

NVPLPPQTR

6.88

-4.62

-6.61

REPNEPPPP

8.88

-3.47

-5.46
Q12451

AAPKHAPPP

9.47

-3.72

-5.71

PHLLPWLPP

10.70

-2.91

-4.90

LLPWLPPTD

11.25

-2.59

-4.58
P15891

SAAPPPPPR

9.80

-1.97

-3.96

AAPPPPPRR

9.92

-1.34

-3.33

DEPEGEPDV

10.15

-3.18

-5.17
P48562

THVQPVAPK

7.47

-2.05

-4.04

PSPSPLNPY

9.73

-1.34

-3.33

SAPRAPYPS

9.93

-2.69

-4.68
P40341

SRNIPPPPP

9.40

-2.47

-4.46

NDPSNPVSK

10.73

-2.62

-4.61

PPPKPPLND

10.82

-2.53

-4.52
Q08912

DHPKGPPPP

7.79

-5.58

-7.57

HPKGPPPPP

11.23

-2.61

-4.60

THGDHPKGP

11.92

-0.66

-2.65
P17555

PRPKKPSTL

9.77

-2.39

-4.38

AAPAPPPPP

10.51

-3.26

-5.25

RPKKPSTLK

10.57

-0.70

-2.69
Q12342

RKAKAPPPP

9.11

-2.78

-4.77

KAKAPPPPP

10.43

-2.85

-4.84

ETPSTPSDG

12.25

-3.73

-5.72
P47068

PEPISPETK

8.29

-1.80

-3.79

PNTAPPLPR

9.11

-2.92

-4.91

DPSSNPFFR

9.16

-3.18

-5.17
P38822

PAPEVPPPR

4.95

-4.73

-6.72

APEVPPPRR

6.46

-3.03

-5.02

DTPTTTPGS

13.13

-2.94

-4.93
P04050

LPVPPPPVR

10.43

-1.48

-3.47

TSPNYSPTS

10.90

-1.70

-3.69

CLPVPPPPV

10.93

-2.40

-4.39
P40450

SSPKLFPRL

8.25

-4.03

-6.02

PPPLPDLFK

8.51

-3.24

-5.23

KLPQLPPPP

9.54

-3.70

-5.69
P40453

KVPEPPSWK

7.83

-2.60

-4.59

TTPEIPPPL

9.14

-2.90

-4.89

LRKRPPPPP

9.47

-2.89

-4.88
Q12168

DDPYFPQFR

5.54

-4.41

-6.40

RGPPPLPPR

9.48

-4.32

-6.31

KVQHPVPKP

10.24

-1.92

-3.91
P41832

DSPAPPPPP

8.98

-4.28

-6.27

DGVIPPAPP

10.37

-3.42

-5.41

PPPPPVPAK

11.27

-0.55

-2.54
P36006

SNKKPKNPG

9.13

-3.11

-5.10

NIPIPPPPP

9.79

-4.59

-6.58

PMGQPKDPK

10.08

-0.43

-2.42
P38753

NTPVMPPQR

6.44

-4.10

-6.09

SPPVPGPAL

10.83

-1.67

-3.66

TPVMPPQRQ

10.92

-0.33

-2.32
P38237

NDPFVPPPN

10.22

-3.78

-5.77

PDLNDPFVP

10.92

-2.48

-4.47

VPPPNVPKK

11.70

-2.51

-4.50
P34245

STPFGPWPG

10.39

-2.43

-4.42

FGPWPGPAE

12.67

-2.33

-4.32
Q01389

RYPQTPSYY

9.74

-3.01

-5.00

SKPLPPQLL

10.23

-2.85

-4.84

KREAPKPPA

10.28

-2.81

-4.80
Q03306

SEPSSPPPI

9.47

-2.67

-4.66

EKPFRIPSS

9.55

-5.40

-7.39

SPPLPQMEF

9.67

-3.71

-5.70
P34758

HLPPPPPPR

9.58

-2.55

-4.54

QQPQHLPPP

10.54

-4.00

-5.99

SQPNKPNYG

10.55

-1.69

-3.68
P53933

SYPGNPTSR

8.91

-2.05

-4.04

KRVAPPPLP

10.10

-3.13

-5.12

VAPPPLPNR

10.95

-0.92

-2.91
Q00453

YFPHPMPSA

9.47

-4.37

-6.36

APPYFPHPM

9.64

-3.69

-5.68

SAPIPLPHQ

10.15

-2.62

-4.61
P40021

SPPLPPPAR

3.99

-5.42

-7.41

PPPLPPPLF

8.86

-4.12

-6.11

HPPNHPHSQ

10.93

-2.84

-4.83
P36150

PIVVNPSSP

12.27

-0.34

-2.33

IVVNPSSPS

12.69

-0.15

-2.14
Q04439

NIPTPPQNR

8.53

-2.69

-4.68

KPKEPMFEA

9.36

-4.47

-6.46

KKPAPPPPG

9.44

-3.73

-5.72
Q12446

LPPASPEVR

7.85

-2.17

-4.16

SNMSSPPPP

9.32

-2.88

-4.87

RNNRPVPPP

9.50

-3.49

-5.48
Q01560

QPPEPQPYY

8.81

-4.88

-6.87

SAPQEPPAP

9.88

-2.76

-4.75

PQPYYPPPP

9.96

-3.68

-5.67
P00950

RSFDVPPPP

13.21

-3.73

-5.72
P53735

PKLVPPPPR

4.98

-3.00

-4.99

PAPKLVPPP

8.25

-3.89

-5.88

APKLVPPPP

10.29

-3.28

-5.27
P33334

GGPKFEPLY

7.96

-4.28

-6.27

DLALPPPPP

9.12

-4.93

-6.92

SDLALPPPP

9.31

-2.59

-4.58
P40523

VPPLAPPPH

9.64

-4.31

-6.30

PVPVGVPPL

10.09

-3.23

-5.22

APPGTVPNM

10.23

-2.82

-4.81
P40563

VTPKVPERP

10.74

-2.34

-4.33

RAPPPVPKK

10.83

-1.64

-3.63

PPPVPKKPS

11.25

-3.07

-5.06
Q08989

DHPKGPPPP

7.79

-5.58

-7.57

HPKGPPPPP

11.23

-2.61

-4.60

PPPPDEKGR

11.96

-2.69

-4.68
P37370

SAPKVPQNR

5.36

-2.87

-4.86

NRPHMPSVR

7.60

-2.33

-4.32

ISPSINPPK

8.12

-2.27

-4.26
P39743

SNPLTSPVA

11.02

-3.77

-5.76
Q03900

HLPNTPSGA

11.92

-1.91

-3.90

NTPSGAPKL

12.29

-3.21

-5.20

TPSGAPKLK

13.02

0.07

-1.92

 


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