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Matrix information:
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ADAN-name: MYO5_1RUW-26.PDB
Scoring matrix: MYO5_1RUW-26_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.44
Foldx random average score for Saccharomyces cerevisiae: 11.794 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1328751
Proteins after disorder filtering: 4329
Total fragments: 55883
Proteins after pattern filtering: 2075
Total fragments: 9366
Proteins after MINT filtering: 44
Total fragments: 501 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
14.44
|
0.28 |
0.00 |
| Best peptides |
DRRKRRFPW |
0.00
|
-2.14 |
-2.42 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
NEPLLPPLP |
9.93
|
-3.81 |
-4.09 |
|
EPLLPPLPG |
10.07
|
-4.61 |
-4.89 |
|
PLPGQPPLI |
11.03
|
-2.66 |
-2.94 |
| P39113 |
GPRRPQKNR |
6.83
|
-3.84 |
-4.12 |
|
SHRGPRRPQ |
7.89
|
-2.47 |
-2.75 |
|
MSPLGAPPP |
9.66
|
-4.27 |
-4.55 |
| P40073 |
GYPQQQPSH |
8.96
|
-4.75 |
-5.03 |
| P25604 |
LPPKPKSPH |
6.10
|
-3.60 |
-3.88 |
|
KPPLPPPPP |
8.07
|
-4.72 |
-5.00 |
|
KSPHLKPPL |
8.26
|
-1.82 |
-2.10 |
| P25623 |
TKPLPVEPA |
10.04
|
-3.72 |
-4.00 |
|
NLPKTVPIS |
10.14
|
-3.43 |
-3.71 |
|
FTPSEVPPS |
10.16
|
-3.37 |
-3.65 |
| Q05933 |
KFRGPAYPS |
9.62
|
-4.22 |
-4.50 |
|
FPVDPNTDR |
10.78
|
-3.18 |
-3.46 |
|
HSTFPVDPN |
10.87
|
-1.00 |
-1.28 |
| P53094 |
DPVSPKPVS |
7.62
|
-3.47 |
-3.75 |
|
REPNEPPPP |
8.12
|
-3.22 |
-3.50 |
|
FPQSPIRAY |
8.62
|
-2.97 |
-3.25 |
| Q12451 |
AAPKHAPPP |
9.12
|
-4.04 |
-4.32 |
|
LLPWLPPTD |
10.67
|
-3.29 |
-3.57 |
|
PHLLPWLPP |
10.85
|
-3.52 |
-3.80 |
| P15891 |
ATPEKKPKE |
8.71
|
-3.95 |
-4.23 |
|
KEPVKTPSP |
9.25
|
-3.88 |
-4.16 |
|
EVPEDEPEG |
9.35
|
-3.95 |
-4.23 |
| P48562 |
IGPAPRPPS |
7.55
|
-4.05 |
-4.33 |
|
FPRGPMHPN |
8.42
|
-3.45 |
-3.73 |
|
QRTAPKPPI |
8.66
|
-2.95 |
-3.23 |
| P40341 |
NSRNIPPPP |
8.61
|
-2.92 |
-3.20 |
|
SRNIPPPPP |
10.06
|
-2.48 |
-2.76 |
|
KPPLNDPSN |
10.16
|
-3.87 |
-4.15 |
| Q08912 |
DHPKGPPPP |
7.70
|
-5.12 |
-5.40 |
|
HPKGPPPPP |
9.43
|
-3.06 |
-3.34 |
|
YTPSWGPSP |
11.54
|
-2.52 |
-2.80 |
| P17555 |
PPPRPKKPS |
7.67
|
-4.15 |
-4.43 |
|
AAPAPPPPP |
9.84
|
-3.63 |
-3.91 |
|
RPKKPSTLK |
10.23
|
-2.56 |
-2.84 |
| Q12342 |
RKAKAPPPP |
8.50
|
-3.73 |
-4.01 |
|
KAKAPPPPP |
9.49
|
-3.63 |
-3.91 |
| P47068 |
APPLPRAPP |
8.17
|
-3.55 |
-3.83 |
|
DPSSNPFFR |
8.23
|
-3.18 |
-3.46 |
|
VDPSSNPFF |
8.77
|
-3.26 |
-3.54 |
| P38822 |
PAPEVPPPR |
6.64
|
-4.94 |
-5.22 |
|
APEVPPPRR |
7.97
|
-2.80 |
-3.08 |
|
DTPTTTPGS |
10.21
|
-3.50 |
-3.78 |
| P04050 |
PPVRPSISF |
9.20
|
-3.51 |
-3.79 |
|
CLPVPPPPV |
10.23
|
-3.08 |
-3.36 |
|
TSPNYSPTS |
11.13
|
-2.60 |
-2.88 |
| P40450 |
LPQLPPPPP |
8.83
|
-3.76 |
-4.04 |
|
PKLFPRLSS |
9.16
|
-5.15 |
-5.43 |
|
SSPKLFPRL |
9.18
|
-3.49 |
-3.77 |
| P40453 |
RLRKRPPPP |
5.92
|
-4.66 |
-4.94 |
|
PPDLPIRLR |
7.53
|
-4.90 |
-5.18 |
|
EPPSWKPPD |
7.62
|
-4.91 |
-5.19 |
| Q12168 |
DDPYFPQFR |
7.10
|
-3.42 |
-3.70 |
|
QHPVPKPNI |
8.19
|
-4.48 |
-4.76 |
|
DPYFPQFRS |
8.94
|
-2.50 |
-2.78 |
| P41832 |
DSPAPPPPP |
8.43
|
-4.43 |
-4.71 |
|
DGVIPPAPP |
9.62
|
-1.67 |
-1.95 |
|
LSSQPPPPP |
10.73
|
-3.38 |
-3.66 |
| P36006 |
SNKKPKNPG |
8.22
|
-3.72 |
-4.00 |
|
QPKDPKFEA |
8.37
|
-4.40 |
-4.68 |
|
TANIPIPPP |
9.34
|
-4.07 |
-4.35 |
| P38753 |
NTPVMPPQR |
8.21
|
-4.24 |
-4.52 |
|
PSNLPIQHP |
11.00
|
-2.69 |
-2.97 |
|
SPPVPGPAL |
11.04
|
-1.99 |
-2.27 |
| P38237 |
NDPFVPPPN |
9.57
|
-3.68 |
-3.96 |
|
DPFVPPPNV |
10.01
|
-3.04 |
-3.32 |
|
PDLNDPFVP |
11.29
|
-3.38 |
-3.66 |
| P34245 |
STPFGPWPG |
10.46
|
-2.64 |
-2.92 |
|
TPFGPWPGP |
11.21
|
-2.40 |
-2.68 |
|
AYSTPFGPW |
11.44
|
0.46 |
0.18 |
| Q01389 |
KREAPKPPA |
8.07
|
-3.08 |
-3.36 |
|
PKREAPKPP |
9.38
|
-5.20 |
-5.48 |
|
RYPQTPSYY |
9.50
|
-3.61 |
-3.89 |
| Q03306 |
EKPFRIPSS |
7.09
|
-5.96 |
-6.24 |
|
SPPLPQMEF |
7.22
|
-3.70 |
-3.98 |
|
SIPRTKPNV |
8.04
|
-4.57 |
-4.85 |
| P34758 |
PQHLPPPPP |
9.95
|
-1.79 |
-2.07 |
|
PSPNPTPSN |
9.95
|
-3.66 |
-3.94 |
|
QQPQHLPPP |
10.07
|
-4.26 |
-4.54 |
| P53933 |
RTRRRPPPP |
6.25
|
-3.31 |
-3.59 |
|
TRRRPPPPP |
7.15
|
-4.80 |
-5.08 |
|
KRVAPPPLP |
9.54
|
-2.98 |
-3.26 |
| P32381 |
LLTEPPMNP |
11.71
|
-2.06 |
-2.34 |
| Q00453 |
APPYFPHPM |
9.28
|
-3.15 |
-3.43 |
|
YFPHPMPSA |
9.79
|
-4.08 |
-4.36 |
|
SAPIPLPHQ |
10.01
|
-4.09 |
-4.37 |
| P40021 |
SPPLPPPAR |
6.36
|
-4.64 |
-4.92 |
|
PPPLPPPLF |
6.51
|
-4.90 |
-5.18 |
|
HPPNHPHSQ |
10.09
|
-2.53 |
-2.81 |
| Q04439 |
KPKEPMFEA |
7.53
|
-5.00 |
-5.28 |
|
PSSKPKEPM |
8.28
|
-2.55 |
-2.83 |
|
HSKKPAPPP |
8.39
|
-3.40 |
-3.68 |
| Q12446 |
PFPFPIPEI |
7.75
|
-5.29 |
-5.57 |
|
QPQSNPFPF |
8.13
|
-3.10 |
-3.38 |
|
RLPAPPPPP |
8.52
|
-3.97 |
-4.25 |
| Q01560 |
QPPEPQPYY |
8.26
|
-4.75 |
-5.03 |
|
PQPYYPPPP |
9.43
|
-4.49 |
-4.77 |
|
PPPSNAPIY |
9.69
|
-3.91 |
-4.19 |
| P00950 |
RSFDVPPPP |
9.23
|
-4.10 |
-4.38 |
|
SFDVPPPPI |
11.05
|
-1.20 |
-1.48 |
| P53735 |
PKLVPPPPR |
7.80
|
-4.09 |
-4.37 |
|
PAPKLVPPP |
8.38
|
-4.84 |
-5.12 |
|
APKLVPPPP |
9.08
|
-3.76 |
-4.04 |
| P33334 |
PSLNPIPHF |
6.84
|
-4.65 |
-4.93 |
|
PTRFPPAVF |
7.65
|
-2.24 |
-2.52 |
|
GGPKFEPLY |
7.90
|
-4.34 |
-4.62 |
| P40523 |
VPPLAPPPH |
7.49
|
-4.45 |
-4.73 |
|
GGPLASPTH |
9.02
|
-3.48 |
-3.76 |
|
ITPLPTPVP |
9.48
|
-4.64 |
-4.92 |
| P40563 |
KRRAPPPVP |
8.44
|
-6.16 |
-6.44 |
|
PPPVPKKPS |
8.48
|
-3.63 |
-3.91 |
|
PSERPKRRA |
8.99
|
-1.12 |
-1.40 |
| Q08989 |
DHPKGPPPP |
7.70
|
-5.12 |
-5.40 |
|
HPKGPPPPP |
9.43
|
-3.06 |
-3.34 |
| P37370 |
KVPQNRPHM |
6.79
|
-4.82 |
-5.10 |
|
VSQMPKPRP |
7.30
|
-4.49 |
-4.77 |
|
QMPKPRPFQ |
7.51
|
-4.66 |
-4.94 |
| P39743 |
SNPLTSPVA |
10.81
|
-3.14 |
-3.42 |
| Q03900 |
PSGAPKLKN |
11.14
|
-0.66 |
-0.94 |
|
HLPNTPSGA |
11.48
|
-1.67 |
-1.95 |
|
