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Matrix information:
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ADAN-name: MYO5_1RUW-20.PDB
Scoring matrix: MYO5_1RUW-20_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.32
Foldx random average score for Saccharomyces cerevisiae: 15.628 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1559548
Proteins after disorder filtering: 4516
Total fragments: 62891
Proteins after pattern filtering: 1943
Total fragments: 6211
Proteins after MINT filtering: 38
Total fragments: 235 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
16.32
|
-3.46 |
0.00 |
| Best peptides |
RMPMRGHHY |
0.00
|
-5.58 |
-2.13 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PGQPPLINI |
14.51
|
-4.47 |
-1.01 |
|
PLLPPLPGQ |
15.13
|
-3.11 |
0.35 |
| P39113 |
HRGPRRPQK |
9.99
|
-4.01 |
-0.55 |
|
FTHPEGPNC |
11.12
|
-2.67 |
0.79 |
|
PRRPQKNRY |
11.31
|
-5.79 |
-2.34 |
| P25604 |
DGSSPHSIP |
14.11
|
-2.37 |
1.09 |
|
HLKPPLPPP |
14.11
|
-5.90 |
-2.45 |
|
PSLPPKPNT |
15.36
|
-3.35 |
0.10 |
| P25623 |
PASPSISLP |
13.56
|
-3.43 |
0.02 |
|
QTFTPSEVP |
13.63
|
-2.55 |
0.91 |
|
NLPKTVPIS |
14.22
|
-3.47 |
-0.02 |
| Q05933 |
PGTPGFPLN |
14.63
|
-3.59 |
-0.13 |
|
FRGPAYPSN |
14.96
|
-2.45 |
1.00 |
|
PVDPNTDRM |
15.39
|
-3.81 |
-0.35 |
| Q08989 |
GDHPKGPPP |
13.43
|
-4.35 |
-0.89 |
| Q12451 |
AAPKHAPPP |
15.13
|
-4.27 |
-0.81 |
|
HLLPWLPPT |
15.24
|
-3.43 |
0.02 |
| P15891 |
RRATPEKKP |
8.75
|
-4.48 |
-1.03 |
|
ISPKPFSKP |
11.76
|
-5.84 |
-2.38 |
|
KSFTPSKSP |
12.35
|
-5.01 |
-1.55 |
| P48562 |
GQFPRGPMH |
8.27
|
-5.78 |
-2.33 |
|
PLNPYRPHH |
10.36
|
-4.01 |
-0.55 |
|
PYRPHHNMI |
12.25
|
-5.01 |
-1.55 |
| Q08912 |
YTPSWGPSP |
10.49
|
-4.89 |
-1.43 |
|
GDHPKGPPP |
13.43
|
-4.35 |
-0.89 |
|
VCYTPSWGP |
13.86
|
-2.76 |
0.70 |
| P17555 |
SGPPPRPKK |
13.91
|
-3.29 |
0.17 |
|
RPKKPSTLK |
14.31
|
-2.69 |
0.77 |
|
PAPPASVFE |
15.27
|
-2.63 |
0.83 |
| P47068 |
YHPMPNTAP |
11.54
|
-6.24 |
-2.79 |
|
YYVPPGIPT |
13.01
|
-4.17 |
-0.71 |
|
DKVPPHPVP |
13.10
|
-5.20 |
-1.75 |
| P38822 |
RGPAPEVPP |
14.22
|
-3.76 |
-0.30 |
| P04050 |
SYSPTSPNY |
13.08
|
-2.06 |
1.40 |
|
NYSPTSPSY |
13.52
|
-2.15 |
1.31 |
|
GVSSPGFSP |
14.28
|
-3.20 |
0.25 |
| P40450 |
SSPKLFPRL |
10.80
|
-3.94 |
-0.48 |
|
VSSSPKLFP |
13.70
|
-2.55 |
0.91 |
|
LVTPPAPPL |
13.78
|
-5.39 |
-1.93 |
| P40453 |
WKPPDLPIR |
9.74
|
-4.41 |
-0.96 |
|
PDLPIRLRK |
12.41
|
-2.69 |
0.77 |
|
AWDCPRCGP |
15.05
|
-3.84 |
-0.38 |
| Q12168 |
NDDPYFPQF |
12.13
|
-2.15 |
1.31 |
|
QHPVPKPNI |
12.69
|
-5.42 |
-1.96 |
|
RGPPPLPPR |
13.24
|
-4.67 |
-1.21 |
| P36006 |
MGQPKDPKF |
11.76
|
-3.67 |
-0.21 |
|
PMGQPKDPK |
15.31
|
-3.13 |
0.33 |
|
PKDPKFEAA |
15.60
|
-1.55 |
1.91 |
| P38753 |
YSPYPSNLP |
11.80
|
-5.12 |
-1.67 |
|
PYPSNLPIQ |
13.78
|
-2.30 |
1.16 |
|
PSNLPIQHP |
14.46
|
-3.97 |
-0.52 |
| P38237 |
FVPPPNVPK |
15.52
|
-3.59 |
-0.13 |
| P34245 |
YSTPFGPWP |
8.34
|
-4.95 |
-1.50 |
|
FGPWPGPAE |
14.89
|
-1.38 |
2.08 |
|
PWPGPAECL |
14.97
|
-2.71 |
0.75 |
| Q01389 |
EEAPTKPNP |
13.05
|
-5.61 |
-2.16 |
|
KRSKPLPPQ |
13.13
|
-4.92 |
-1.46 |
|
RRYPQTPSY |
14.08
|
-4.21 |
-0.75 |
| Q03306 |
GEEKPFRIP |
10.61
|
-5.24 |
-1.79 |
|
RQPTPSPPL |
10.92
|
-4.92 |
-1.46 |
|
NKSIPRTKP |
12.10
|
-5.58 |
-2.13 |
| P34758 |
NQQQPQHLP |
9.87
|
-4.64 |
-1.18 |
|
QQLPLEPLK |
11.24
|
-3.65 |
-0.19 |
|
HSQPNKPNY |
11.91
|
-4.04 |
-0.58 |
| P53933 |
YNDLPMELP |
10.65
|
-6.56 |
-3.10 |
|
VAPPPLPNR |
12.58
|
-4.38 |
-0.92 |
|
NDLPMELPH |
15.32
|
-1.29 |
2.17 |
| P32381 |
LTEPPMNPL |
14.77
|
-3.84 |
-0.38 |
| Q00453 |
YAPPYFPHP |
8.00
|
-5.78 |
-2.33 |
|
HQPPPLPIY |
10.23
|
-6.21 |
-2.75 |
|
SAPIPLPHQ |
12.74
|
-3.97 |
-0.52 |
| P40021 |
SHPPNHPHS |
11.74
|
-1.95 |
1.51 |
|
LNSPPLPPP |
14.19
|
-5.49 |
-2.04 |
|
PLPPPARSQ |
14.94
|
-3.38 |
0.08 |
| Q04439 |
SSKPKEPMF |
12.19
|
-4.20 |
-0.75 |
|
GSGSPSELP |
13.07
|
-3.15 |
0.31 |
|
HSKKPAPPP |
14.11
|
-4.42 |
-0.96 |
| Q12446 |
SNPFPFPIP |
10.94
|
-3.87 |
-0.42 |
|
PQLPNRNNR |
12.62
|
-3.81 |
-0.35 |
|
QSAPSAPIP |
12.72
|
-4.31 |
-0.85 |
| Q01560 |
HHQPPEPQP |
11.20
|
-4.20 |
-0.75 |
|
PQEPPAPQE |
14.29
|
-2.93 |
0.52 |
|
PQAPDAPQE |
14.57
|
-1.89 |
1.57 |
| P33334 |
GGPKFEPLY |
10.17
|
-3.61 |
-0.15 |
|
NAIPGGPKF |
11.36
|
-2.93 |
0.52 |
|
LFFDPSLNP |
11.89
|
-2.67 |
0.79 |
| P40523 |
LGAPPGTVP |
11.16
|
-5.25 |
-1.79 |
|
LAPPPHGPF |
14.31
|
-4.87 |
-1.42 |
|
PHGPFSTSM |
14.46
|
-2.77 |
0.69 |
| P40563 |
GMVNPGQLP |
9.03
|
-5.97 |
-2.51 |
|
RAPPPVPKK |
12.80
|
-4.87 |
-1.42 |
|
PSERPKRRA |
12.92
|
-2.50 |
0.96 |
| P53094 |
LKLPPLPLT |
10.62
|
-4.97 |
-1.51 |
|
SAFPQSPIR |
12.20
|
-3.44 |
0.02 |
|
DEDPVSPKP |
13.14
|
-3.59 |
-0.13 |
| P37370 |
KVPQNRPHM |
7.59
|
-4.37 |
-0.92 |
|
AVTPGGPLP |
9.66
|
-4.88 |
-1.42 |
|
QMPKPRPFQ |
9.94
|
-6.16 |
-2.71 |
| P39743 |
NATIPEDNP |
13.66
|
-4.05 |
-0.59 |
| Q03900 |
NTPSGAPKL |
14.46
|
-0.39 |
3.06 |
|
PNTPSGAPK |
15.27
|
-1.30 |
2.16 |
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