ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1RUW-2.PDB
Scoring matrix: MYO5_1RUW-2_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.17
Foldx random average score for Saccharomyces cerevisiae: 18.378

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1554145
Proteins after disorder filtering: 4480
 Total fragments: 92272
Proteins after pattern filtering: 2294
 Total fragments: 20810
Proteins after MINT filtering: 45
 Total fragments: 1370

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.17

0.53

0.00
Best peptides

FRKRMFRDRW

0.00

2.01

1.48
         
Interactors      
P53145

LLPPLPGQPP

12.80

-5.45

-5.98

PLPGQPPLIN

14.20

-3.44

-3.97

NEPLLPPLPG

15.65

-4.29

-4.82
P39113

HRGPRRPQKN

10.39

-4.53

-5.06

PLGAPPPPPH

10.64

-7.44

-7.97

SHRGPRRPQK

11.25

-3.75

-4.28
P40073

QFDGYPQQQP

15.16

-0.72

-1.25

FDGYPQQQPS

17.18

-1.94

-2.47
P25604

LKPPLPPPPP

9.69

-6.42

-6.95

PHLKPPLPPP

9.96

-3.49

-4.02

PKPKSPHLKP

10.21

-3.20

-3.73
P25623

AQTFTPSEVP

12.85

-2.35

-2.88

SKTKPLPVEP

13.92

-1.48

-2.01

SISQPPLQPQ

14.28

-3.95

-4.48
Q05933

FRGPAYPSNS

10.56

-3.85

-4.38

TKFRGPAYPS

11.72

-2.14

-2.67

FPVDPNTDRM

13.16

-4.61

-5.14
P53094

FKSSAFPQSP

9.75

-3.06

-3.59

YPLKLPPLPL

10.74

-6.39

-6.92

TREPNEPPPP

12.28

-3.78

-4.31
Q12451

PKHAPPPVPN

12.84

-5.44

-5.97

QPHLLPWLPP

13.44

-4.38

-4.91

APKHAPPPVP

13.51

-4.88

-5.41
P15891

KKSFTPSKSP

10.78

-1.45

-1.98

SRSSAAPPPP

10.82

-3.74

-4.27

PRRATPEKKP

10.96

-4.69

-5.22
P48562

QPQRTAPKPP

11.07

-5.52

-6.05

NPYRPHHNMI

11.15

-4.49

-5.02

QTMRQAPKRP

11.55

-3.58

-4.11
P40341

SRNIPPPPPP

9.46

-4.61

-5.14

NIPPPPPPPP

10.40

-5.54

-6.07

IPPPPPPPPP

12.64

-6.81

-7.34
Q08912

DHPKGPPPPP

9.51

-4.03

-4.56

PKGPPPPPPP

10.41

-5.81

-6.34

HPKGPPPPPP

11.02

-7.87

-8.40
P17555

SKSGPPPRPK

10.55

-5.56

-6.09

PRPKKPSTLK

11.09

-4.24

-4.77

APPPPPPAPP

13.13

-5.42

-5.95
Q12342

RKAKAPPPPP

8.45

-5.73

-6.26

AKAPPPPPPP

10.25

-4.97

-5.50

APPPPPPPPP

12.66

-6.57

-7.10
P47068

PLPRAPPVPP

9.06

-7.52

-8.05

SRTLPPHVPS

11.61

-2.84

-3.37

SIPPVPPTPP

12.00

-5.49

-6.02
P38822

DRGPAPEVPP

11.40

-3.73

-4.26

APEVPPPRRS

14.18

-3.65

-4.18

PAPEVPPPRR

14.48

-5.12

-5.65
P04050

CLPVPPPPVR

12.04

-5.42

-5.95

LPVPPPPVRP

12.53

-5.03

-5.56

SPGFSPTSPT

13.75

-3.30

-3.83
P40450

QLPPPPPPPP

10.43

-5.55

-6.08

KLPQLPPPPP

11.29

-6.70

-7.23

LPQLPPPPPP

11.82

-7.76

-8.29
P40453

LRKRPPPPPP

5.64

-6.65

-7.18

IRLRKRPPPP

6.57

-4.57

-5.10

RLRKRPPPPP

8.94

-7.80

-8.33
Q12168

NRGPPPLPPR

10.23

-4.79

-5.32

NKVQHPVPKP

12.19

-2.94

-3.47

QHPVPKPNID

14.28

-0.94

-1.47
P41832

PKGETPPPPP

11.07

-5.34

-5.87

QPPPPPPPPP

11.99

-5.83

-6.36

APPPPPPPPP

12.66

-6.57

-7.10
P36006

NIPIPPPPPP

10.48

-5.53

-6.06

PKDPKFEAAY

12.04

-4.60

-5.13

PIPPPPPPMG

12.21

-7.01

-7.54
P38753

AHISPPVPGP

13.90

-1.78

-2.31

NTPVMPPQRQ

14.35

-2.50

-3.03

HANNTPVMPP

14.97

-3.97

-4.50
P38237

DLNDPFVPPP

12.42

-4.84

-5.37

QIPSKPENTV

14.34

-2.44

-2.97

DPFVPPPNVP

14.39

-3.06

-3.59
P34245

STPFGPWPGP

14.24

-1.66

-2.19

AYSTPFGPWP

15.52

-1.36

-1.89

GPWPGPAECL

17.12

-2.71

-3.24
Q01389

APKREAPKPP

11.50

-7.77

-8.30

PKREAPKPPA

11.86

-4.70

-5.23

SRPVPPDSSY

11.96

-2.16

-2.69
Q03306

YRQPTPSPPL

9.05

-5.31

-5.84

PRTKPNVPPL

10.91

-4.13

-4.66

SIPRTKPNVP

11.09

-1.08

-1.61
P34758

QHLPPPPPPR

10.23

-4.39

-4.92

HLPPPPPPRA

10.25

-6.68

-7.21

QPQHLPPPPP

12.36

-6.39

-6.92
P53933

TRRRPPPPPI

6.92

-5.19

-5.72

VRTRRRPPPP

9.11

-6.03

-6.56

RRRPPPPPIP

9.20

-4.90

-5.43
P32381

LLTEPPMNPL

12.89

-6.22

-6.75

ILLTEPPMNP

13.44

-4.92

-5.45
Q00453

FPHPMPSAPI

11.59

-4.02

-4.55

SLYAPPYFPH

12.33

-4.04

-4.57

PHQPPPLPIY

12.50

-2.70

-3.23
P40021

FLPSTPSQMN

11.52

-4.05

-4.58

SLDFLPSTPS

11.80

-3.32

-3.85

TKNTGPPPPL

11.85

-4.55

-5.08
P36150

PIVVNPSSPS

13.75

-4.18

-4.71

NPIVVNPSSP

16.42

-3.22

-3.75
Q04439

RHSKKPAPPP

10.00

-2.78

-3.31

NIPPPPPPPP

10.40

-5.54

-6.07

SKPKEPMFEA

11.32

-3.62

-4.15
Q12446

NRPVPPPPPM

8.90

-6.52

-7.05

TKHKAPPPPP

9.37

-4.85

-5.38

RRGPAPPPPP

9.46

-6.14

-6.67
Q01560

HHQPPEPQPY

11.92

-4.04

-4.57

QHHQPPEPQP

12.08

-0.26

-0.79

YYPPPPPGEH

12.34

-3.62

-4.15
P00950

RRSFDVPPPP

14.21

-2.52

-3.05

SFDVPPPPID

14.65

0.23

-0.30

RSFDVPPPPI

15.13

-3.80

-4.33
P53735

PKLVPPPPRT

11.34

-4.63

-5.16

APKLVPPPPR

12.77

-7.26

-7.79

KLVPPPPRTR

12.79

-4.04

-4.57
P33334

MPTRFPPAVF

9.14

-6.37

-6.90

FLPPPPPPPS

10.57

-6.59

-7.12

ALPPPPPPPP

11.10

-6.06

-6.59
P40523

PLAPPPHGPF

11.49

-5.48

-6.01

YMHNSPRNPD

11.66

-5.30

-5.83

NITPLPTPVP

12.04

-3.08

-3.61
P40563

PKRRAPPPVP

7.82

-5.71

-6.24

KRRAPPPVPK

9.91

-5.57

-6.10

RRAPPPVPKK

10.94

-3.49

-4.02
Q08989

DHPKGPPPPP

9.51

-4.03

-4.56

PKGPPPPPPP

10.41

-5.81

-6.34

HPKGPPPPPP

11.02

-7.87

-8.40
P37370

NRPHMPSVRP

9.20

-1.82

-2.35

PKPRPFQNKT

10.14

-3.48

-4.01

NPTKSPPPPP

10.63

-7.35

-7.88
P39743

PNATIPEDNP

16.09

-2.17

-2.70
Q03900

HLPNTPSGAP

11.83

-5.11

-5.64

TPSGAPKLKN

16.27

-3.12

-3.65

LPNTPSGAPK

16.61

-3.85

-4.38

 


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