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Matrix information:
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ADAN-name: MYO5_1RUW-11.PDB
Scoring matrix: MYO5_1RUW-11_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.72
Foldx random average score for Saccharomyces cerevisiae: 11.668 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3221900
Proteins after random average filtering: 7179
Total fragments: 1350212
Proteins after disorder filtering: 4552
Total fragments: 62580
Proteins after pattern filtering: 1958
Total fragments: 7121
Proteins after MINT filtering: 42
Total fragments: 474 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
12.72
|
1.56 |
0.00 |
| Best peptides |
YMWRPPR |
0.00
|
-2.72 |
-4.29 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
NEPLLPP |
9.64
|
-2.77 |
-4.34 |
|
PLLPPLP |
10.89
|
-3.27 |
-4.84 |
|
LLPPLPG |
11.05
|
-2.04 |
-3.61 |
| P39113 |
RGPRRPQ |
6.32
|
-2.69 |
-4.25 |
|
GPRRPQK |
8.04
|
0.14 |
-1.42 |
|
GAPPPPP |
10.73
|
-2.34 |
-3.90 |
| P40073 |
PQQQPSH |
10.51
|
-3.03 |
-4.59 |
| P25604 |
APSLPPK |
8.90
|
-2.27 |
-3.84 |
|
PHLKPPL |
9.43
|
-2.25 |
-3.81 |
|
PLPPKPK |
9.61
|
-2.74 |
-4.30 |
| P25623 |
PLPVEPA |
9.99
|
-2.04 |
-3.61 |
|
PSEVPPS |
10.40
|
-3.33 |
-4.89 |
|
PKTVPIS |
10.41
|
-2.79 |
-4.36 |
| Q05933 |
RGPAYPS |
10.54
|
-1.22 |
-2.79 |
|
LPGTPGF |
11.05
|
-1.95 |
-3.51 |
| P53094 |
REPNEPP |
8.02
|
-2.35 |
-3.92 |
|
PLKLPPL |
9.19
|
-4.23 |
-5.79 |
|
NVPLPPQ |
9.85
|
-1.01 |
-2.58 |
| Q12451 |
LLPWLPP |
9.20
|
-2.33 |
-3.90 |
|
AAPKHAP |
9.71
|
-2.06 |
-3.63 |
|
PHLLPWL |
9.95
|
-1.94 |
-3.50 |
| P15891 |
AAPPPPP |
8.48
|
-2.90 |
-4.46 |
|
APPPPPR |
8.87
|
0.21 |
-1.36 |
|
QPPLPSR |
9.05
|
-2.07 |
-3.63 |
| P48562 |
PAPRPPS |
6.57
|
-3.65 |
-5.21 |
|
SAPRAPY |
6.79
|
-0.42 |
-1.98 |
|
QFPRGPM |
7.64
|
-0.76 |
-2.33 |
| P40341 |
RNIPPPP |
8.64
|
-4.03 |
-5.60 |
|
NIPPPPP |
10.04
|
-1.93 |
-3.50 |
|
PPPPPPK |
11.60
|
-2.17 |
-3.73 |
| Q08912 |
KGPPPPP |
9.99
|
-3.57 |
-5.13 |
|
PKGPPPP |
10.20
|
-3.15 |
-4.71 |
|
YTPSWGP |
10.27
|
-1.38 |
-2.94 |
| P17555 |
PPPRPKK |
7.62
|
-1.42 |
-2.98 |
|
AAPAPPP |
8.78
|
-2.51 |
-4.07 |
|
PAPPPPP |
10.37
|
-3.26 |
-4.82 |
| Q12342 |
AKAPPPP |
8.15
|
-2.93 |
-4.50 |
|
KAPPPPP |
9.47
|
-3.72 |
-5.29 |
|
APPPPPP |
11.47
|
0.60 |
-0.96 |
| P47068 |
PLPRAPP |
7.79
|
-2.50 |
-4.06 |
|
PSSNPFF |
9.03
|
-2.25 |
-3.81 |
|
TAPPLPR |
9.05
|
-1.91 |
-3.47 |
| P38822 |
PEVPPPR |
7.39
|
-4.37 |
-5.94 |
|
APEVPPP |
10.53
|
-1.17 |
-2.73 |
| P04050 |
CLPVPPP |
8.77
|
-3.38 |
-4.95 |
|
APTSPGF |
9.76
|
0.14 |
-1.42 |
|
PPVRPSI |
9.81
|
-1.01 |
-2.58 |
| P40450 |
AVPPPPP |
8.48
|
-2.31 |
-3.88 |
|
AAPAPPP |
8.78
|
-2.51 |
-4.07 |
|
QLPPPPP |
9.23
|
-3.34 |
-4.90 |
| P40453 |
RKRPPPP |
7.84
|
-4.44 |
-6.01 |
|
DCPRCGP |
7.91
|
-0.63 |
-2.19 |
|
KRPPPPP |
8.68
|
-4.28 |
-5.85 |
| Q12168 |
DDPYFPQ |
8.66
|
0.56 |
-1.00 |
|
QHPVPKP |
8.73
|
-1.78 |
-3.34 |
|
RGPPPLP |
9.36
|
-2.83 |
-4.39 |
| P41832 |
SQPPPPP |
10.18
|
-1.04 |
-2.61 |
|
DSPAPPP |
10.34
|
-2.28 |
-3.84 |
|
PAPPPPP |
10.37
|
-3.26 |
-4.82 |
| P36006 |
NIPIPPP |
8.10
|
-3.05 |
-4.62 |
|
PIPPPPP |
9.72
|
-2.41 |
-3.98 |
|
GQPKDPK |
10.05
|
-1.28 |
-2.84 |
| P38753 |
PVMPPQR |
8.63
|
-3.20 |
-4.77 |
|
PSNLPIQ |
11.10
|
-2.57 |
-4.13 |
|
HISPPVP |
11.28
|
-1.70 |
-3.26 |
| P38237 |
QIPSKPE |
11.04
|
-0.56 |
-2.13 |
|
PFVPPPN |
11.05
|
-2.46 |
-4.03 |
|
LNDPFVP |
11.18
|
-1.18 |
-2.75 |
| P34245 |
FGPWPGP |
8.71
|
-2.33 |
-3.90 |
|
YSTPFGP |
9.53
|
-2.79 |
-4.36 |
| Q01389 |
SKPLPPQ |
9.07
|
-3.54 |
-5.11 |
|
REAPKPP |
9.28
|
-3.01 |
-4.57 |
|
ASPTSPK |
9.50
|
-0.62 |
-2.19 |
| Q03306 |
RQPTPSP |
8.03
|
-4.17 |
-5.73 |
|
SIPRTKP |
8.57
|
-0.50 |
-2.06 |
|
PFRIPSS |
9.02
|
-3.04 |
-4.61 |
| P34758 |
QLPLEPL |
8.72
|
-1.92 |
-3.48 |
|
PQHLPPP |
9.20
|
-4.26 |
-5.82 |
|
QHLPPPP |
9.83
|
-1.51 |
-3.08 |
| P53933 |
RRPPPPP |
7.54
|
-4.06 |
-5.63 |
|
RRRPPPP |
7.78
|
-5.65 |
-7.21 |
|
DLPMELP |
8.62
|
-1.79 |
-3.36 |
| P32381 |
TEPPMNP |
11.59
|
-1.31 |
-2.88 |
| Q00453 |
YFPHPMP |
7.96
|
-3.79 |
-5.36 |
|
PHPMPSA |
9.19
|
-2.72 |
-4.29 |
|
SAPIPLP |
9.19
|
-2.36 |
-3.92 |
| P40021 |
PLPPPAR |
7.94
|
-2.86 |
-4.42 |
|
PLPPPLF |
7.99
|
-3.42 |
-4.98 |
|
LNSPPLP |
10.79
|
-2.71 |
-4.28 |
| Q04439 |
ARPSPPT |
8.40
|
-2.62 |
-4.19 |
|
ANIPPPP |
8.80
|
-3.23 |
-4.79 |
|
KKPAPPP |
9.04
|
-4.76 |
-6.32 |
| Q12446 |
RLPAPPP |
8.21
|
-3.91 |
-5.47 |
|
FAPLPDP |
8.45
|
-3.53 |
-5.09 |
|
AAPPPPP |
8.48
|
-2.90 |
-4.46 |
| Q01560 |
YYPPPPP |
7.74
|
-4.53 |
-6.10 |
|
PEPQPYY |
7.88
|
-2.97 |
-4.54 |
|
PQPYYPP |
9.19
|
-2.70 |
-4.27 |
| P00950 |
FDVPPPP |
9.37
|
-3.60 |
-5.17 |
|
DVPPPPI |
9.97
|
-0.35 |
-1.92 |
| P53735 |
LVPPPPR |
7.29
|
-2.54 |
-4.11 |
|
PKLVPPP |
8.87
|
-3.72 |
-5.29 |
|
KLVPPPP |
9.54
|
-3.62 |
-5.19 |
| P33334 |
ALPPPPP |
8.07
|
-3.12 |
-4.69 |
|
PKFEPLY |
8.68
|
-2.45 |
-4.02 |
|
FLPPPPP |
8.89
|
-4.00 |
-5.56 |
| P40523 |
NSPRNPD |
9.55
|
-0.34 |
-1.91 |
|
PVGVPPL |
9.85
|
-3.08 |
-4.64 |
|
ITPLPTP |
9.88
|
-2.20 |
-3.77 |
| P40563 |
PSERPKR |
4.32
|
-2.02 |
-3.59 |
|
RAPPPVP |
9.00
|
-3.44 |
-5.00 |
|
PPPVPKK |
10.92
|
-1.95 |
-3.51 |
| Q08989 |
KGPPPPP |
9.99
|
-3.57 |
-5.13 |
|
PKGPPPP |
10.20
|
-3.15 |
-4.71 |
|
DHPKGPP |
11.38
|
0.53 |
-1.03 |
| P37370 |
PKPRPFQ |
6.04
|
-3.59 |
-5.15 |
|
PQNRPHM |
6.54
|
-3.73 |
-5.29 |
|
QMPKPRP |
7.78
|
-3.80 |
-5.37 |
|
