ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO5_1R6S-25.PDB
Scoring matrix: MYO5_1R6S-25_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.09
Foldx random average score for Saccharomyces cerevisiae: 17.691

Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
 Proteins belonging to other specie: 0
Nš of interactions described: 108
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1441913
Proteins after disorder filtering: 4588
 Total fragments: 94474
Proteins after pattern filtering: 2259
 Total fragments: 16486
Proteins after MINT filtering: 45
 Total fragments: 1142

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.09

19.55

0.00
Best peptides

RRPPKGTRG

0.00

1.73

-17.82
         
Interactors      
P53145

EPLLPPLPG

10.60

2.92

-16.63

LLPPLPGQP

11.76

3.55

-16.00

NEPLLPPLP

14.17

5.04

-14.51
P39113

PRRPQKNRY

10.35

2.03

-17.52

HRGPRRPQK

12.18

3.64

-15.91

RGPRRPQKN

13.27

4.81

-14.74
P40073

GYPQQQPSH

15.41

4.36

-15.19

YPQQQPSHT

15.54

8.34

-11.21

DGYPQQQPS

17.54

7.50

-12.05
P25604

PLPPKPKSP

11.01

3.58

-15.97

SLPPKPNTQ

12.10

3.06

-16.49

LKPPLPPPP

12.13

1.72

-17.83
P25623

DTPPLPPHA

10.59

2.55

-17.00

PLPVEPASP

13.90

5.73

-13.82

PLPPHATPK

13.93

4.68

-14.87
Q05933

NFTLPGTPG

9.32

3.37

-16.18

TLPGTPGFP

12.82

4.78

-14.77

TKFRGPAYP

14.92

5.21

-14.34
P53094

PQSPIRAYG

8.31

1.66

-17.89

AFPQSPIRA

10.97

3.60

-15.95

PPCPAMSTG

13.13

4.44

-15.11
Q12451

APPPVPNET

15.44

6.04

-13.51

KHAPPPVPN

15.45

5.16

-14.39

HLLPWLPPT

15.74

6.25

-13.30
P15891

EVPEDEPEG

8.33

3.05

-16.50

APPPPPRRA

11.31

3.52

-16.03

AQPPLPSRN

12.37

3.28

-16.27
P48562

LNPYRPHHN

11.80

3.69

-15.86

RQAPKRPDA

12.08

3.94

-15.61

QFPRGPMHP

12.48

6.27

-13.28
P40341

PPPPKPPLN

11.63

2.29

-17.26

NIPPPPPPP

12.31

4.09

-15.46

PPPPPPPKP

13.27

4.47

-15.08
Q08912

PSWGPSPMG

12.42

4.94

-14.61

DHPKGPPPP

13.09

5.93

-13.62

GDHPKGPPP

14.03

6.97

-12.58
P17555

GPPPRPKKP

11.35

3.71

-15.84

PAPPPPPPA

13.42

4.15

-15.40

SKSGPPPRP

13.64

4.77

-14.78
Q12342

ETPSTPSDG

10.08

1.53

-18.02

TPSTPSDGG

13.13

5.60

-13.95

KAPPPPPPP

14.04

3.64

-15.91
P47068

SVPPVPPVP

12.51

4.63

-14.92

PVPPVPPVS

12.82

5.30

-14.25

SIPPVPPTP

12.95

4.10

-15.45
P38822

DRGPAPEVP

14.83

5.20

-14.35

PAPEVPPPR

14.91

3.06

-16.49

PEVPPPRRS

14.97

5.72

-13.83
P04050

EAPTSPGFG

8.78

2.11

-17.44

PVPPPPVRP

11.61

5.30

-14.25

PTSPGYSPG

11.69

3.44

-16.11
P40450

PPAPPLPNG

11.29

3.32

-16.23

KLPQLPPPP

12.40

2.81

-16.74

QLPPPPPPP

12.63

3.20

-16.35
P40453

RLRKRPPPP

10.66

2.16

-17.39

KVPEPPSWK

12.31

6.03

-13.52

RKRPPPPPP

12.71

3.73

-15.82
Q12168

GPPPLPPRA

10.50

1.62

-17.93

PPPVPNRPG

10.63

2.39

-17.16

IPPPVPNRP

11.51

4.63

-14.92
P41832

PPPPMALFG

6.41

0.77

-18.78

VIPPAPPMM

11.86

3.40

-16.15

PPPPPPPMA

12.29

3.01

-16.54
P36006

NKKPKNPGG

7.17

1.62

-17.93

IPPPPPPMG

7.42

0.65

-18.90

SNKKPKNPG

10.60

3.70

-15.85
P38753

AHISPPVPG

9.66

2.46

-17.09

NTPVMPPQR

12.68

2.54

-17.01

ISPPVPGPA

13.11

2.77

-16.78
P38237

QIPSKPENT

11.64

6.57

-12.98

ENFQIPSKP

13.71

4.88

-14.67

PFVPPPNVP

15.09

6.91

-12.64
P34245

STPFGPWPG

9.58

2.38

-17.17

PFGPWPGPA

14.15

5.52

-14.03

YSTPFGPWP

15.76

8.49

-11.06
Q01389

APTKPNPQG

12.34

3.36

-16.19

RYPQTPSYY

12.46

3.95

-15.60

STPSRPVPP

12.86

5.11

-14.44
Q03306

TKPNVPPLQ

13.19

2.41

-17.14

IPRTKPNVP

13.30

5.87

-13.68

PPLPQMEFP

13.55

5.06

-14.49
P34758

SQPNKPNYG

4.53

-0.02

-19.57

LPPPPPPRA

10.92

2.54

-17.01

QLPLEPLKP

11.86

5.32

-14.23
P53933

RTRRRPPPP

12.06

3.15

-16.40

RRPPPPPIP

12.63

3.64

-15.91

APPPLPNRQ

12.65

5.03

-14.52
P32381

LLTEPPMNP

16.13

5.97

-13.58
Q00453

YNLPISTPA

13.13

4.83

-14.72

YAPPYFPHP

13.19

6.13

-13.42

QPPPLPIYS

13.34

4.00

-15.55
P40021

SHPPNHPHS

12.41

6.88

-12.67

NSPPLPPPA

12.97

3.92

-15.63

FLPSTPSQM

13.49

2.03

-17.52
P36150

PIVVNPSSP

17.09

5.09

-14.46
Q04439

KKPAPPPPG

7.09

0.20

-19.35

RHSKKPAPP

11.82

5.34

-14.21

ARPSPPTAA

12.23

3.92

-15.63
Q12446

APPPPPRRG

6.45

1.33

-18.22

PPPPPASLG

9.65

2.38

-17.17

PAPPPPPRA

11.39

3.18

-16.37
Q01560

PYYPPPPPG

8.21

1.16

-18.39

PPPPPGEHM

12.65

4.31

-15.24

HQPPEPQPY

12.67

2.40

-17.15
P00950

DVPPPPIDA

12.50

4.57

-14.98

RSFDVPPPP

15.46

4.50

-15.05

PPPPIDASS

15.54

6.54

-13.01
P53735

VPPPPRTRS

13.14

5.71

-13.84

KLVPPPPRT

13.38

4.50

-15.05

APKLVPPPP

15.33

5.07

-14.48
P33334

LPPPPPPPG

8.09

0.63

-18.92

PPPPPPPPG

8.18

0.74

-18.81

KMPTRFPPA

9.63

2.44

-17.11
P40523

PPLAPPPHG

8.87

2.63

-16.92

NSPRNPDTG

11.15

3.28

-16.27

APPPHGPFS

12.99

5.70

-13.85
P40563

VTPKVPERP

11.62

2.86

-16.69

APPPVPKKP

12.77

4.57

-14.98

KRRAPPPVP

13.13

4.68

-14.87
Q08989

PPPPPDEKG

8.90

2.16

-17.39

DHPKGPPPP

13.09

5.93

-13.62

GDHPKGPPP

14.03

6.97

-12.58
P37370

SAPPIPGMG

6.09

-0.11

-19.66

PPPPPPPPG

8.18

0.74

-18.81

PPPPPPALG

8.37

1.38

-18.17
P39743

SNPLTSPVA

15.57

5.88

-13.67

AYSNPLTSP

17.26

6.78

-12.77
Q03900

SHLPNTPSG

13.25

5.19

-14.36

HLPNTPSGA

13.34

3.48

-16.07

PNTPSGAPK

16.98

8.35

-11.20

 


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