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Matrix information:
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ADAN-name: MYO5_1R6S-23.PDB
Scoring matrix: MYO5_1R6S-23_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.14
Foldx random average score for Saccharomyces cerevisiae: 10.066 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3221900
Proteins after random average filtering: 7179
Total fragments: 1353381
Proteins after disorder filtering: 4480
Total fragments: 55820
Proteins after pattern filtering: 1836
Total fragments: 6958
Proteins after MINT filtering: 42
Total fragments: 492 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
13.14
|
-0.58 |
0.00 |
| Best peptides |
RPLIPWH |
0.00
|
-4.07 |
-3.49 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
EPLLPPL |
7.36
|
-4.52 |
-3.94 |
|
PLLPPLP |
8.50
|
-4.30 |
-3.72 |
|
LPPLPGQ |
8.95
|
-3.87 |
-3.29 |
| P39113 |
RGPRRPQ |
6.05
|
-3.22 |
-2.64 |
|
GPRRPQK |
7.97
|
-2.57 |
-1.99 |
|
PPPPPHK |
8.26
|
-2.24 |
-1.66 |
| P40073 |
YPQQQPS |
9.38
|
-1.42 |
-0.84 |
|
PQQQPSH |
9.85
|
-2.05 |
-1.47 |
| P25604 |
KSPHLKP |
7.13
|
-3.12 |
-2.54 |
|
KPPLPPP |
7.57
|
-3.62 |
-3.04 |
|
KPKSPHL |
7.61
|
-2.69 |
-2.11 |
| P25623 |
KPLPVEP |
6.44
|
-3.29 |
-2.71 |
|
TPPLPPH |
7.34
|
-2.83 |
-2.25 |
|
PPLPPHA |
7.92
|
-3.37 |
-2.79 |
| Q05933 |
FTLPGTP |
8.81
|
-3.73 |
-3.15 |
|
FRGPAYP |
9.46
|
-0.15 |
0.43 |
|
RGPAYPS |
9.85
|
-1.80 |
-1.22 |
| P53094 |
YPLKLPP |
6.28
|
-3.75 |
-3.17 |
|
LKLPPLP |
7.83
|
-4.51 |
-3.93 |
|
KLPPLPL |
7.91
|
0.13 |
0.71 |
| Q12451 |
PHLLPWL |
5.53
|
-4.77 |
-4.19 |
|
HLLPWLP |
7.43
|
-2.71 |
-2.13 |
|
APKHAPP |
9.20
|
-1.71 |
-1.13 |
| P15891 |
KPEVPED |
7.65
|
-2.52 |
-1.94 |
|
PPPPPRR |
8.21
|
-3.31 |
-2.73 |
|
PPLPSRN |
8.29
|
-3.22 |
-2.64 |
| P48562 |
NPYRPHH |
6.53
|
-1.50 |
-0.92 |
|
RGPMHPN |
6.82
|
-3.67 |
-3.09 |
|
KPPISAP |
6.95
|
-3.50 |
-2.92 |
| P40341 |
RNIPPPP |
6.33
|
-2.42 |
-1.84 |
|
KPPLNDP |
8.54
|
-4.12 |
-3.54 |
|
PPPPPPK |
9.17
|
-3.56 |
-2.98 |
| Q08912 |
KGPPPPP |
8.45
|
-1.65 |
-1.07 |
|
PPPPDEK |
9.33
|
-4.18 |
-3.60 |
| P17555 |
RPKKPST |
7.23
|
-3.05 |
-2.47 |
|
PPPRPKK |
7.56
|
-3.85 |
-3.27 |
|
PPRPKKP |
9.23
|
-1.52 |
-0.94 |
| Q12342 |
KAPPPPP |
8.32
|
-2.00 |
-1.42 |
| P47068 |
RAPPVPP |
7.96
|
-2.03 |
-1.45 |
|
APSPPPH |
8.61
|
-1.03 |
-0.45 |
|
PSPPPHQ |
8.79
|
-2.60 |
-2.02 |
| P38822 |
PEVPPPR |
9.53
|
-2.18 |
-1.60 |
|
APEVPPP |
10.01
|
-0.60 |
-0.02 |
| P04050 |
PPVRPSI |
9.34
|
-2.84 |
-2.26 |
|
TCLPVPP |
9.50
|
-2.41 |
-1.83 |
|
VPPPPVR |
9.66
|
-1.67 |
-1.09 |
| P40450 |
PKLFPRL |
7.64
|
-5.76 |
-5.18 |
|
PPLPESL |
8.10
|
-3.96 |
-3.38 |
|
PPLPQSL |
8.41
|
-4.18 |
-3.60 |
| P40453 |
RKRPPPP |
6.64
|
-3.56 |
-2.98 |
|
RPPPPPP |
7.23
|
-1.63 |
-1.05 |
|
PDLPIRL |
7.31
|
-3.47 |
-2.89 |
| Q12168 |
RGPPPLP |
7.28
|
-2.41 |
-1.83 |
|
PPLPPRA |
7.97
|
-4.38 |
-3.80 |
|
PPPLPPR |
8.61
|
-4.15 |
-3.57 |
| P41832 |
PPAPPMM |
8.65
|
-2.61 |
-2.03 |
|
PPMMPAS |
8.72
|
-5.43 |
-4.85 |
|
PPLPSVL |
8.75
|
-3.91 |
-3.33 |
| P36006 |
IPIPPPP |
8.28
|
-4.10 |
-3.52 |
|
NIPIPPP |
8.60
|
-1.06 |
-0.48 |
|
KPKNPGG |
9.06
|
-3.29 |
-2.71 |
| P38753 |
TPVMPPQ |
7.96
|
-2.76 |
-2.18 |
|
NLPIQHP |
8.09
|
-1.25 |
-0.67 |
|
YPSNLPI |
8.33
|
-1.75 |
-1.17 |
| P38237 |
FQIPSKP |
7.51
|
-3.95 |
-3.37 |
|
PPNVPKK |
8.63
|
-2.30 |
-1.72 |
|
IPSKPEN |
9.66
|
-1.62 |
-1.04 |
| P34245 |
YSTPFGP |
9.09
|
-1.27 |
-0.69 |
|
FGPWPGP |
9.22
|
-2.43 |
-1.85 |
|
TPFGPWP |
10.00
|
-0.72 |
-0.14 |
| Q01389 |
KPLPPQL |
5.65
|
-3.11 |
-2.53 |
|
RSKPLPP |
7.55
|
-2.43 |
-1.85 |
|
YPQTPSY |
7.85
|
-1.94 |
-1.36 |
| Q03306 |
KPNVPPL |
7.23
|
-2.88 |
-2.30 |
|
KPFRIPS |
7.83
|
-1.92 |
-1.34 |
|
PPLPQME |
7.99
|
-2.61 |
-2.03 |
| P34758 |
LPLEPLK |
7.83
|
-4.91 |
-4.33 |
|
QHLPPPP |
8.59
|
-2.93 |
-2.35 |
|
QQLPLEP |
8.81
|
-3.80 |
-3.22 |
| P53933 |
RRRPPPP |
6.61
|
-3.32 |
-2.74 |
|
RPPPPPI |
6.83
|
-2.47 |
-1.89 |
|
RRPPPPP |
7.27
|
-2.93 |
-2.35 |
| P32381 |
EPPMNPL |
8.79
|
-2.88 |
-2.30 |
| Q00453 |
YFPHPMP |
5.54
|
-3.37 |
-2.79 |
|
APIPLPH |
7.29
|
-2.37 |
-1.79 |
|
YAPPYFP |
7.70
|
-3.39 |
-2.81 |
| P40021 |
HPPNHPH |
7.54
|
-2.31 |
-1.73 |
|
PPLPPPL |
7.66
|
-4.24 |
-3.66 |
|
PPLPPPA |
8.83
|
-3.02 |
-2.44 |
| Q04439 |
KPKEPMF |
7.14
|
-3.54 |
-2.96 |
|
RPSPPTA |
8.48
|
0.43 |
1.01 |
|
KPAPPPP |
8.51
|
-0.75 |
-0.17 |
| Q12446 |
RPLPQLP |
5.81
|
-5.65 |
-5.07 |
|
HSLPPLP |
6.85
|
-2.15 |
-1.57 |
|
FPIPEIP |
7.57
|
-4.16 |
-3.58 |
| Q01560 |
YYPPPPP |
7.83
|
-2.38 |
-1.80 |
|
YPPPPPG |
8.03
|
-2.34 |
-1.76 |
|
PPPPGEH |
8.51
|
-0.08 |
0.50 |
| P00950 |
FDVPPPP |
9.07
|
-3.52 |
-2.94 |
| P53735 |
PKLVPPP |
8.23
|
-4.24 |
-3.66 |
|
KLVPPPP |
8.75
|
-1.75 |
-1.17 |
|
LVPPPPR |
9.16
|
-2.54 |
-1.96 |
| P33334 |
FTLPPPP |
7.51
|
-4.11 |
-3.53 |
|
TFLPPPP |
8.34
|
-2.64 |
-2.06 |
|
LALPPPP |
8.41
|
-3.55 |
-2.97 |
| P40523 |
TPLPTPV |
8.84
|
-1.66 |
-1.08 |
|
PLAPPPH |
9.07
|
-0.82 |
-0.24 |
|
PPPHGPF |
9.46
|
-1.57 |
-0.99 |
| P40563 |
TPKVPER |
7.38
|
-3.31 |
-2.73 |
|
PSERPKR |
8.00
|
-2.23 |
-1.65 |
|
RAPPPVP |
8.12
|
-0.52 |
0.06 |
| Q08989 |
KGPPPPP |
8.45
|
-1.65 |
-1.07 |
|
PPPPDEK |
9.33
|
-4.18 |
-3.60 |
| P37370 |
RPHMPSV |
6.36
|
-3.71 |
-3.13 |
|
PPIPTSH |
7.60
|
-3.12 |
-2.54 |
|
PKPRPFQ |
7.84
|
-3.46 |
-2.88 |
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