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Matrix information:
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ADAN-name: MYO5_1R6S-12.PDB
Scoring matrix: MYO5_1R6S-12_mat
Uniprot code: Q04439
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.32
Foldx random average score for Saccharomyces cerevisiae: 12.112 Available information for Q04439 in MINT (Nov 2008):
Nš of interacting proteins: 61
Proteins belonging to other specie: 0
Nš of interactions described: 108
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1377910
Proteins after disorder filtering: 4554
Total fragments: 66159
Proteins after pattern filtering: 2119
Total fragments: 11105
Proteins after MINT filtering: 45
Total fragments: 848 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
15.32
|
-1.21 |
0.00 |
| Best peptides |
YRRPPFWR |
0.00
|
-3.39 |
-2.18 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P53145 |
PGQPPLIN |
9.48
|
-2.88 |
-1.67 |
|
PLLPPLPG |
9.49
|
-3.24 |
-2.03 |
|
PNEPLLPP |
10.39
|
-2.55 |
-1.34 |
| P39113 |
PRRPQKNR |
5.90
|
-3.12 |
-1.91 |
|
SHRGPRRP |
6.95
|
-2.86 |
-1.65 |
|
HRGPRRPQ |
7.98
|
-1.52 |
-0.31 |
| P40073 |
DGYPQQQP |
11.31
|
-2.52 |
-1.31 |
| P25604 |
HLKPPLPP |
7.01
|
-4.04 |
-2.83 |
|
PSLPPKPN |
9.22
|
-3.34 |
-2.13 |
|
PKSPHLKP |
9.50
|
-2.44 |
-1.23 |
| P25623 |
ISQPPLQP |
9.53
|
-2.70 |
-1.49 |
|
SDTPPLPP |
10.07
|
-3.09 |
-1.88 |
|
DTPPLPPH |
10.68
|
-2.58 |
-1.37 |
| Q05933 |
PGTPGFPL |
8.93
|
-3.10 |
-1.89 |
|
FRGPAYPS |
9.38
|
-2.25 |
-1.04 |
|
KFRGPAYP |
10.68
|
-1.48 |
-0.27 |
| P53094 |
LKLPPLPL |
8.37
|
-4.27 |
-3.06 |
|
DPVSPKPV |
9.52
|
-1.88 |
-0.67 |
|
CYPLKLPP |
9.63
|
-3.45 |
-2.24 |
| Q12451 |
HLLPWLPP |
9.88
|
-3.31 |
-2.10 |
|
QPHLLPWL |
10.61
|
-2.91 |
-1.70 |
|
PHLLPWLP |
10.62
|
-3.16 |
-1.95 |
| P15891 |
PPPPPRRA |
7.18
|
-4.46 |
-3.25 |
|
PPPPRRAT |
8.87
|
-3.98 |
-2.77 |
|
KKEPVKTP |
9.18
|
-0.87 |
0.34 |
| P48562 |
VAKPKKPA |
7.99
|
-2.15 |
-0.94 |
|
RQAPKRPD |
8.24
|
-2.57 |
-1.36 |
|
IGPAPRPP |
8.36
|
-3.11 |
-1.90 |
| P40341 |
PPKPPLND |
8.55
|
-4.26 |
-3.05 |
|
RNIPPPPP |
8.59
|
-2.63 |
-1.42 |
|
PPPPPKPP |
8.93
|
-2.45 |
-1.24 |
| Q08912 |
KGPPPPPP |
9.84
|
-2.92 |
-1.71 |
|
CYTPSWGP |
10.20
|
-2.96 |
-1.75 |
|
GPPPPPPP |
11.21
|
-2.74 |
-1.53 |
| P17555 |
SGPPPRPK |
6.87
|
-3.77 |
-2.56 |
|
PPRPKKPS |
8.18
|
-2.29 |
-1.08 |
|
PKKPSTLK |
9.74
|
-2.33 |
-1.12 |
| Q12342 |
KAPPPPPP |
9.81
|
-3.00 |
-1.79 |
|
KAKAPPPP |
10.46
|
-2.59 |
-1.38 |
|
AKAPPPPP |
10.78
|
-2.17 |
-0.96 |
| P47068 |
PSSNPFFR |
7.99
|
-2.92 |
-1.71 |
|
PHVPSLTN |
8.38
|
-4.15 |
-2.94 |
|
NTAPPLPR |
8.67
|
-3.27 |
-2.06 |
| P38822 |
PEVPPPRR |
9.14
|
-3.77 |
-2.56 |
| P04050 |
PPPPVRPS |
8.54
|
-3.33 |
-2.12 |
|
PVRPSISF |
9.06
|
-2.55 |
-1.34 |
|
VSSPGFSP |
9.29
|
-2.65 |
-1.44 |
| P40450 |
SSPKLFPR |
8.00
|
-3.77 |
-2.56 |
|
PAPPPLPD |
8.17
|
-4.09 |
-2.88 |
|
PKLFPRLS |
8.49
|
-2.94 |
-1.73 |
| P40453 |
WKPPDLPI |
7.02
|
-4.24 |
-3.03 |
|
RKRPPPPP |
7.41
|
-3.07 |
-1.86 |
|
EIPPPLPP |
7.75
|
-4.26 |
-3.05 |
| Q12168 |
PYFPQFRS |
6.28
|
-4.47 |
-3.26 |
|
RGPPPLPP |
7.45
|
-4.05 |
-2.84 |
|
PPVPNRPG |
8.23
|
-3.97 |
-2.76 |
| P41832 |
PAPPMMPA |
8.91
|
-4.41 |
-3.20 |
|
PPPPPLPS |
8.91
|
-4.08 |
-2.87 |
|
GVIPPAPP |
9.64
|
-2.97 |
-1.76 |
| P36006 |
QPKDPKFE |
8.77
|
-2.76 |
-1.55 |
|
PKDPKFEA |
9.26
|
-2.71 |
-1.50 |
|
PPPPPMGQ |
9.28
|
-4.67 |
-3.46 |
| P38753 |
PVMPPQRQ |
8.75
|
-4.13 |
-2.92 |
|
PYPSNLPI |
9.42
|
-3.34 |
-2.13 |
|
AHISPPVP |
10.82
|
-2.97 |
-1.76 |
| P38237 |
FQIPSKPE |
6.75
|
-1.94 |
-0.73 |
|
PFVPPPNV |
10.47
|
-3.87 |
-2.66 |
|
DLNDPFVP |
10.96
|
-3.29 |
-2.08 |
| P34245 |
STPFGPWP |
9.31
|
-3.25 |
-2.04 |
|
TPFGPWPG |
10.72
|
-2.74 |
-1.53 |
|
AYSTPFGP |
10.85
|
-1.94 |
-0.73 |
| Q01389 |
PLPPQLLS |
8.62
|
-3.86 |
-2.65 |
|
PSYPSIFR |
8.65
|
-2.23 |
-1.02 |
|
SQFPNLTP |
8.71
|
-3.75 |
-2.54 |
| Q03306 |
EEKPFRIP |
6.44
|
-4.40 |
-3.19 |
|
PNVPPLQT |
8.52
|
-4.06 |
-2.85 |
|
KSIPRTKP |
9.17
|
-2.19 |
-0.98 |
| P34758 |
PPPPPRAQ |
8.46
|
-4.61 |
-3.40 |
|
PNKPNYGM |
8.71
|
-3.80 |
-2.59 |
|
HSQPNKPN |
9.78
|
-1.52 |
-0.31 |
| P53933 |
RRRPPPPP |
6.90
|
-3.04 |
-1.83 |
|
VAPPPLPN |
8.06
|
-4.17 |
-2.96 |
|
RRPPPPPI |
8.38
|
-3.39 |
-2.18 |
| P32381 |
LTEPPMNP |
10.00
|
-2.83 |
-1.62 |
|
TEPPMNPL |
11.70
|
-2.23 |
-1.02 |
| Q00453 |
YAPPYFPH |
6.37
|
-4.50 |
-3.29 |
|
HQPPPLPI |
7.93
|
-4.34 |
-3.13 |
|
LYAPPYFP |
8.29
|
-3.97 |
-2.76 |
| P40021 |
PLPPPLFP |
6.78
|
-4.35 |
-3.14 |
|
LPPPLFPS |
7.97
|
-4.25 |
-3.04 |
|
GPPPPLPP |
8.82
|
-4.10 |
-2.89 |
| P36150 |
IVVNPSSP |
11.90
|
-1.98 |
-0.77 |
| Q04439 |
KPKEPMFE |
8.04
|
-4.10 |
-2.89 |
|
PKEPMFEA |
8.71
|
-2.28 |
-1.07 |
|
SKKPAPPP |
9.00
|
-2.61 |
-1.40 |
| Q12446 |
PPPPPRRG |
7.26
|
-4.40 |
-3.19 |
|
PPPPHRHV |
7.62
|
-3.33 |
-2.12 |
|
PPPPAFLT |
7.72
|
-4.79 |
-3.58 |
| Q01560 |
YYPPPPPG |
9.55
|
-3.08 |
-1.87 |
|
PEPQPYYP |
9.62
|
-4.22 |
-3.01 |
|
PYYPPPPP |
10.44
|
-3.04 |
-1.83 |
| P00950 |
FDVPPPPI |
9.99
|
-3.13 |
-1.92 |
|
DVPPPPID |
10.31
|
-3.10 |
-1.89 |
|
VPPPPIDA |
11.41
|
-2.84 |
-1.63 |
| P53735 |
VPPPPRTR |
7.45
|
-4.17 |
-2.96 |
|
KLVPPPPR |
9.12
|
-3.93 |
-2.72 |
|
LVPPPPRT |
9.67
|
-3.47 |
-2.26 |
| P33334 |
SKMPTRFP |
4.89
|
-4.67 |
-3.46 |
|
KMPTRFPP |
8.16
|
-3.46 |
-2.25 |
|
PPPPGFEE |
8.78
|
-4.74 |
-3.53 |
| P40523 |
VGVPPLAP |
8.61
|
-4.60 |
-3.39 |
|
PPHGPFST |
9.68
|
-2.46 |
-1.25 |
|
MHNSPRNP |
9.73
|
-2.83 |
-1.62 |
| P40563 |
PPVPKKPS |
9.34
|
-3.53 |
-2.32 |
|
PSERPKRR |
10.05
|
-1.93 |
-0.72 |
|
PPPVPKKP |
10.39
|
-2.08 |
-0.87 |
| Q08989 |
KGPPPPPP |
9.84
|
-2.92 |
-1.71 |
|
PPPPPPPP |
11.18
|
-2.80 |
-1.59 |
|
GPPPPPPP |
11.21
|
-2.74 |
-1.53 |
| P37370 |
QNRPHMPS |
7.45
|
-3.68 |
-2.47 |
|
PKPRPFQN |
7.65
|
-4.47 |
-3.26 |
|
KVPQNRPH |
8.28
|
-2.52 |
-1.31 |
| P39743 |
ATIPEDNP |
10.81
|
-1.95 |
-0.74 |
| Q03900 |
PSGAPKLK |
11.62
|
-0.39 |
0.82 |
|
NTPSGAPK |
12.11
|
-1.10 |
0.11 |
|
