ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-23.PDB
Scoring matrix: MYO3_1ZUY-23_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 14.05
Foldx random average score for Saccharomyces cerevisiae: 10.934

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1402042
Proteins after disorder filtering: 4511
 Total fragments: 56412
Proteins after pattern filtering: 1811
 Total fragments: 6321
Proteins after MINT filtering: 21
 Total fragments: 209

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

14.05

-1.37

0.00

Best peptides

RPLWPWH

0.00

-5.53

-4.17

         
Interactors      
Q12446

LPQLPNR

7.76

-5.76

-4.39

RPLPQLP

8.57

-5.25

-3.88

PPQMPAT

8.57

-4.53

-3.17

P47068

LPPHVPS

9.18

-2.76

-1.39

APPLPRA

9.58

-3.99

-2.63

PEPISPE

9.72

-2.68

-1.32

P39113

RGPRRPQ

7.99

-3.36

-1.99

GPRRPQK

9.31

-3.64

-2.28

MSPLGAP

9.73

-4.97

-3.60

Q01389

YPQTPSY

8.47

-4.54

-3.17

KPLPPQL

8.54

-3.44

-2.08

PPPIPKT

8.66

-3.10

-1.74

P04050

PPVRPSI

10.01

-3.34

-1.97

P40523

PPPHGPF

8.32

-2.27

-0.91

PPLAPPP

9.13

-4.76

-3.39

ITPLPTP

10.36

-3.93

-2.57

P38237

IPSKPEN

9.50

-2.93

-1.57

PPPNVPK

9.62

-4.17

-2.80

PPNVPKK

10.53

-4.26

-2.89

P40450

PKLFPRL

7.49

-5.21

-3.84

LPQLPPP

8.13

-5.47

-4.10

PPPLPDL

8.87

-4.29

-2.92

P40453

PPPLPPK

8.02

-5.42

-4.05

PPSWKPP

8.29

-3.47

-2.11

PPLPPKI

9.01

-3.70

-2.34

P53094

YPLKLPP

6.75

-5.78

-4.42

PLKLPPL

8.65

-4.89

-3.52

LPPLPLT

8.78

-4.76

-3.39

P41832

PPMMPAS

8.64

-4.92

-3.55

IPPAPPM

9.58

-3.02

-1.66

PPPLPSV

9.73

-4.17

-2.80

P40021

PPNHPHS

7.85

-2.48

-1.12

HPPNHPH

9.18

-2.18

-0.82

PPLPPPL

9.19

-3.54

-2.17

Q04439

KPKEPMF

7.14

-5.22

-3.85

SKPKEPM

9.50

-2.50

-1.14

PSSKPKE

9.99

-2.61

-1.24

P37370

RPHMPSV

7.96

-4.71

-3.34

PQNRPHM

8.00

-3.14

-1.78

PSINPPK

8.28

-5.05

-3.68

P40341

PPPKPPL

8.73

-3.31

-1.95

PPLNDPS

9.34

-4.45

-3.09

KPPLNDP

9.54

-5.33

-3.96

Q01560

PEPQPYY

8.35

-4.49

-3.13

PSNAPIY

9.14

-4.11

-2.75

PPPPGEH

10.27

-2.50

-1.14

P39743

NPLTSPV

10.62

-2.87

-1.51

Q08912

TPSWGPS

8.87

-2.01

-0.64

P17555

RPKKPST

7.87

-4.49

-3.13

PPPRPKK

7.88

-3.75

-2.38

PRPKKPS

10.30

-2.98

-1.62

P33334

PKFEPLY

8.72

-3.93

-2.57

PSLNPIP

8.74

-5.10

-3.73

MPTRFPP

9.47

-4.22

-2.85

P25604

PHLKPPL

7.15

-4.49

-3.13

TPPLPPK

7.98

-4.88

-3.51

PKPKSPH

8.17

-3.21

-1.85

 


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