ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-20.PDB
Scoring matrix: MYO3_1ZUY-20_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.28
Foldx random average score for Saccharomyces cerevisiae: 16.169

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1564643
Proteins after disorder filtering: 4561
 Total fragments: 73917
Proteins after pattern filtering: 2081
 Total fragments: 8278
Proteins after MINT filtering: 23
 Total fragments: 233

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.28

-3.48

0.00

Best peptides

RRPKRGHRY

0.00

-5.93

-2.45

         
Interactors      
P39113

PRRPQKNRY

9.83

-7.42

-3.94

HRGPRRPQK

11.27

-7.44

-3.96

FTHPEGPNC

11.94

-3.61

-0.13

P25604

HLKPPLPPP

13.17

-8.05

-4.57

LPPKPKSPH

13.23

-4.43

-0.95

LPPKPNTQL

13.49

-7.20

-3.72

Q08989

GDHPKGPPP

13.49

-6.19

-2.71

PPPPDEKGR

14.57

-3.98

-0.50

P40341

PPKPPLNDP

15.84

-4.91

-1.43

P17555

RPKKPSTLK

10.05

-6.12

-2.64

SGPPPRPKK

14.24

-5.20

-1.72

PPAPPASVF

15.53

-6.11

-2.63

Q08912

YTPSWGPSP

12.24

-7.22

-3.74

GDHPKGPPP

13.49

-6.19

-2.71

PPPPDEKDR

14.03

-3.03

0.45

P47068

YHPMPNTAP

12.86

-7.71

-4.23

NTAPPLPRA

13.17

-4.22

-0.74

YYVPPGIPT

13.33

-6.01

-2.53

P04050

SYSPTSPNY

11.99

-3.56

-0.08

NYSPTSPSY

12.41

-4.38

-0.90

SYSPTSPSY

13.40

-3.78

-0.30

P40450

SSPKLFPRL

10.23

-5.16

-1.68

PPLPNGLLS

13.52

-4.35

-0.87

LVTPPAPPL

14.06

-7.37

-3.89

P40453

WKPPDLPIR

10.38

-5.99

-2.51

PDLPIRLRK

12.98

-3.97

-0.49

VPEPPSWKP

14.13

-5.63

-2.15

P41832

PPPPPMALF

12.83

-7.13

-3.65

GVIPPAPPM

16.16

-6.38

-2.90

P38237

FVPPPNVPK

15.30

-6.20

-2.72

P53094

LKLPPLPLT

12.31

-6.98

-3.50

SAFPQSPIR

12.58

-4.56

-1.08

TREPNEPPP

13.51

-6.86

-3.38

Q01389

RRYPQTPSY

10.00

-6.47

-2.99

RPVPPDSSY

11.77

-5.92

-2.44

KRSKPLPPQ

12.76

-7.00

-3.52

P40021

PSTPSQMNY

13.83

-3.60

-0.12

LNSPPLPPP

14.39

-7.31

-3.83

PLPPPARSQ

15.33

-5.62

-2.14

Q04439

HSKKPAPPP

13.12

-6.19

-2.71

SSKPKEPMF

13.16

-6.05

-2.57

PPPPPSSKP

14.22

-6.13

-2.65

Q12446

PPPRRGPAP

10.82

-6.36

-2.88

RPLPQLPNR

10.94

-4.64

-1.16

PPPPRASRP

11.57

-4.98

-1.50

Q01560

PPPPPGEHM

13.06

-6.74

-3.26

HHQPPEPQP

13.72

-5.56

-2.08

PPPSNAPIY

13.93

-5.53

-2.05

P33334

NAIPGGPKF

9.92

-6.48

-3.00

GGPKFEPLY

10.85

-6.89

-3.41

LFFDPSLNP

12.96

-4.39

-0.91

P40523

LGAPPGTVP

11.91

-6.10

-2.62

LAPPPHGPF

12.79

-6.91

-3.43

VPVPVGVPP

14.45

-4.96

-1.48

P38822

RGPAPEVPP

14.40

-5.72

-2.24

P37370

RPHMPSVRP

8.69

-7.13

-3.65

VSQMPKPRP

10.87

-6.49

-3.01

AVTPGGPLP

11.03

-6.49

-3.01

P39743

AYSNPLTSP

15.64

-4.61

-1.13

NATIPEDNP

15.69

-5.64

-2.16

 


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