ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-19.PDB
Scoring matrix: MYO3_1ZUY-19_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.19
Foldx random average score for Saccharomyces cerevisiae: 16.963

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1663693
Proteins after disorder filtering: 4608
 Total fragments: 80725
Proteins after pattern filtering: 2104
 Total fragments: 7884
Proteins after MINT filtering: 23
 Total fragments: 197

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.19

3.51

0.00

Best peptides

RDKRWGRHY

0.00

-1.00

-4.51

         
Interactors      
P39113

FTHPEGPNC

12.40

-1.57

-5.08

PRRPQKNRY

12.74

-5.31

-8.82

AMSPLGAPP

13.39

-3.83

-7.34

P25604

PKSPHLKPP

15.17

-1.82

-5.33

QNTPPLPPK

15.25

-3.47

-6.98

HLKPPLPPP

15.26

-5.47

-8.98

Q08989

GDHPKGPPP

12.78

-4.31

-7.82

NGDHPKGPP

14.16

-3.04

-6.55

P40341

PLNDPSNPV

16.68

-2.07

-5.58

P17555

SGPPPRPKK

15.63

-3.76

-7.27

PKKPSTLKT

15.98

-0.60

-4.11

PAPPASVFE

16.33

-0.40

-3.91

Q08912

GDHPKGPPP

12.78

-4.31

-7.82

YTPSWGPSP

14.82

-1.21

-4.72

P47068

NTAPPLPRA

12.26

-2.40

-5.91

PLPPVSEEY

12.77

-2.41

-5.92

YYVPPGIPT

13.71

-2.76

-6.27

P04050

NYSPTSPSY

11.15

-2.49

-6.00

AYSPTSPSY

13.02

-3.26

-6.77

SYSPTSPNY

14.31

-1.99

-5.50

P40450

LVTPPAPPL

14.32

-4.75

-8.26

PAPPPLPDL

15.54

-4.07

-7.58

SSPKLFPRL

15.65

-2.16

-5.67

P40453

PDLPIRLRK

11.01

-2.60

-6.11

SWKPPDLPI

14.42

-3.83

-7.34

WKPPDLPIR

14.76

-2.72

-6.23

P41832

GVIPPAPPM

15.52

-4.66

-8.17

P38237

NFQIPSKPE

12.97

1.59

-1.92

FQIPSKPEN

15.02

-0.10

-3.61

FVPPPNVPK

15.24

-1.83

-5.34

P53094

LKLPPLPLT

13.46

-4.52

-8.03

PLPPQTREP

13.93

-3.04

-6.55

DEDPVSPKP

14.71

-2.95

-6.46

Q01389

RRYPQTPSY

11.67

-6.17

-9.68

RTEPSTPSR

13.48

-1.19

-4.70

PSYPSIFRR

14.19

-2.43

-5.94

P40021

PLPPPARSQ

13.53

-3.82

-7.33

PSTPSQMNY

14.63

-4.25

-7.76

ESHPPNHPH

14.99

-2.93

-6.44

Q04439

PTPPQNRDV

15.27

-1.41

-4.92

SSKPKEPMF

15.35

-2.24

-5.75

PKEPMFEAA

15.42

-2.14

-5.65

Q12446

NGGTPGGPP

13.19

-1.73

-5.24

ALPPASPEV

13.55

-1.77

-5.28

RNNRPVPPP

14.31

-6.45

-9.96

Q01560

PQEPPAPQE

13.98

-3.80

-7.31

PDAPQEPQV

14.21

-2.29

-5.80

PQAPDAPQE

14.85

-0.92

-4.43

P33334

NAIPGGPKF

9.43

-4.08

-7.59

GGPKFEPLY

13.19

-4.19

-7.70

PSLNPIPHF

13.72

-2.85

-6.36

P40523

LGAPPGTVP

13.33

-4.68

-8.19

LAPPPHGPF

14.36

-4.29

-7.80

PHGPFSTSM

15.09

-2.65

-6.16

P38822

RGPAPEVPP

14.83

-3.75

-7.26

P37370

KVPQNRPHM

12.41

-2.88

-6.39

AVTPGGPLP

12.65

-3.35

-6.86

LEKPPSPPV

13.18

-4.50

-8.01

P39743

NATIPEDNP

15.76

-2.31

-5.82

YSNPLTSPV

16.26

-1.88

-5.39

AYSNPLTSP

16.32

-2.59

-6.10

 


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