ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-18.PDB
Scoring matrix: MYO3_1ZUY-18_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 18.21
Foldx random average score for Saccharomyces cerevisiae: 16.226

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1500191
Proteins after disorder filtering: 4470
 Total fragments: 75582
Proteins after pattern filtering: 2109
 Total fragments: 10318
Proteins after MINT filtering: 25
 Total fragments: 295

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

18.21

0.75

0.00

Best peptides

RFPLNGHRWR

0.00

-5.64

-6.38

         
Interactors      
P39113

RGPRRPQKNR

9.68

-2.73

-3.48

PRRPQKNRYN

11.25

-1.24

-1.98

SASHRGPRRP

12.42

0.63

-0.11

P36150

PIVVNPSSPS

14.87

-1.69

-2.44

P53094

AFPQSPIRAY

10.22

-1.39

-2.13

YPLKLPPLPL

13.54

-2.60

-3.35

LGVLNVPLPP

14.01

-1.62

-2.37

P40341

KPPLNDPSNP

14.19

-3.51

-4.25

SRNIPPPPPP

14.36

-3.18

-3.93

LNDPSNPVSK

15.87

0.10

-0.65

Q08912

YTPSWGPSPM

12.69

-1.35

-2.10

VCYTPSWGPS

14.91

0.08

-0.67

P17555

SKSGPPPRPK

12.37

-0.78

-1.52

RPKKPSTLKT

13.89

-3.25

-4.00

KSGPPPRPKK

15.94

-0.71

-1.46

P25604

QAPSLPPKPN

13.82

-0.12

-0.86

LPPKPKSPHL

14.29

-1.30

-2.04

PKPKSPHLKP

14.40

2.15

1.40

P47068

SRTLPPHVPS

11.01

-3.02

-3.77

KYYVPPGIPT

11.50

-2.34

-3.09

VDPSSNPFFR

11.92

-1.16

-1.90

P04050

PPVRPSISFN

13.82

-2.61

-3.36

TYSPTSPAYS

14.23

-1.65

-2.40

CLPVPPPPVR

14.55

-2.74

-3.49

P40450

VSSSPKLFPR

13.60

0.46

-0.28

KLPQLPPPPP

14.18

-2.56

-3.31

PPPLPDLFKT

15.04

-3.26

-4.00

P40453

TKVPEPPSWK

12.91

-2.44

-3.19

RLRKRPPPPP

12.94

-3.49

-4.24

WKPPDLPIRL

12.98

-1.24

-1.98

P41832

KGETPPPPPL

14.07

-1.88

-2.63

DGVIPPAPPM

15.33

-1.72

-2.46

LSSQPPPPPP

15.92

-1.32

-2.06

Q12342

RKAKAPPPPP

13.78

-2.69

-3.44

P38237

PFVPPPNVPK

13.83

-1.46

-2.21

ENFQIPSKPE

13.87

0.14

-0.60

NFQIPSKPEN

14.65

-1.73

-2.48

Q01389

RYPQTPSYYY

9.62

-2.52

-3.27

RRYPQTPSYY

11.52

-1.88

-2.63

KRSKPLPPQL

12.05

-1.54

-2.29

P40021

NYVISPNLPT

11.86

-2.31

-3.06

FLPSTPSQMN

13.34

-2.62

-3.37

TKNTGPPPPL

14.09

-1.73

-2.48

Q04439

RHSKKPAPPP

14.36

-2.00

-2.75

PSSKPKEPMF

14.94

-1.64

-2.38

NNNIPTPPQN

15.06

-2.40

-3.15

Q12446

PFPVPQQQFN

11.78

-3.13

-3.88

RLPAPPPPPR

11.85

-3.19

-3.94

NRPLPQLPNR

11.98

-2.92

-3.67

Q01560

HHQPPEPQPY

13.56

-0.22

-0.96

YYPPPPPGEH

14.46

-1.09

-1.84

HQPPEPQPYY

14.54

-0.72

-1.46

P00950

RRSFDVPPPP

14.86

-1.86

-2.61

RSFDVPPPPI

15.70

-1.32

-2.06

P33334

NNAIPGGPKF

12.56

-0.36

-1.11

LFFDPSLNPI

12.77

-1.45

-2.19

NAIPGGPKFE

12.81

-0.74

-1.48

P40523

GGPLASPTHY

12.43

-1.93

-2.67

YMHNSPRNPD

12.98

-1.64

-2.38

ENITPLPTPV

14.09

-0.26

-1.00

P38822

APEVPPPRRS

13.31

-2.32

-3.06

P37370

VSQMPKPRPF

10.63

-2.06

-2.81

RPHMPSVRPA

10.96

-4.31

-5.05

APKVPQNRPH

12.44

-1.88

-2.63

P39743

AYSNPLTSPV

14.80

-1.15

-1.90

 


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