ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-17.PDB
Scoring matrix: MYO3_1ZUY-17_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.93
Foldx random average score for Saccharomyces cerevisiae: 14.774

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1507223
Proteins after disorder filtering: 4552
 Total fragments: 72883
Proteins after pattern filtering: 2026
 Total fragments: 7215
Proteins after MINT filtering: 23
 Total fragments: 209

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.93

-2.50

0.00

Best peptides

RDFMRGHRR

0.00

-5.91

-3.41

         
Interactors      
P39113

HRGPRRPQK

7.92

-4.66

-2.16

FTHPEGPNC

9.50

-3.57

-1.07

PRRPQKNRY

10.59

-5.04

-2.54

P25604

QNTPPLPPK

11.88

-4.96

-2.46

LPPKPNTQL

12.03

-4.17

-1.67

KSPHLKPPL

12.44

-3.90

-1.40

Q08989

GDHPKGPPP

12.89

-4.10

-1.60

PPPPDEKGR

13.43

-3.18

-0.68

P40341

PPPPPKPPL

13.57

-6.01

-3.51

LNDPSNPVS

14.40

-1.13

1.37

P17555

RPKKPSTLK

11.02

-6.26

-3.76

SGPPPRPKK

11.13

-4.22

-1.72

PPAPPASVF

14.58

-4.88

-2.38

Q08912

YTPSWGPSP

11.41

-4.93

-2.43

GDHPKGPPP

12.89

-4.10

-1.60

PPPPDEKDR

13.15

-2.57

-0.07

Q12342

LETPSTPSD

14.52

0.26

2.76

P47068

PHVPSLTNR

11.04

-2.16

0.34

FVDPSSNPF

11.45

-4.06

-1.56

YYVPPGIPT

11.86

-5.27

-2.77

P04050

SYSPTSPNY

11.87

-3.87

-1.37

PPVRPSISF

12.70

-4.35

-1.85

NYSPTSPSY

12.79

-3.79

-1.29

P40450

SSPKLFPRL

11.28

-2.81

-0.31

LVTPPAPPL

11.81

-6.27

-3.77

PAPPPLPDL

12.83

-3.28

-0.78

P40453

PDLPIRLRK

9.20

-2.94

-0.44

WKPPDLPIR

10.16

-4.41

-1.91

EIPPPLPPK

13.10

-6.00

-3.50

P41832

GVIPPAPPM

13.79

-5.52

-3.02

PPPPPVPAK

13.80

-4.29

-1.79

PPPPPMALF

14.17

-6.64

-4.14

P38237

VPPPNVPKK

12.57

-2.78

-0.28

FVPPPNVPK

12.62

-4.97

-2.47

FQIPSKPEN

13.00

-2.59

-0.09

Q01389

RRYPQTPSY

9.78

-6.59

-4.09

RTEPSTPSR

10.99

-4.22

-1.72

PSYPSIFRR

11.10

-1.86

0.64

P40021

PSTPSQMNY

12.36

-3.98

-1.48

LNSPPLPPP

13.41

-6.36

-3.86

Q04439

APPPPGMQN

12.75

-3.61

-1.11

PSSKPKEPM

13.24

-4.35

-1.85

SSKPKEPMF

13.77

-4.09

-1.59

Q12446

RPLPQLPNR

8.16

-5.81

-3.31

PQLPNRNNR

9.75

-3.73

-1.23

PPPRRGPAP

11.11

-4.21

-1.71

Q01560

PPPPPGEHM

11.84

-6.03

-3.53

HHQPPEPQP

12.58

-4.57

-2.07

PDAPQEPQV

12.86

-3.06

-0.56

P33334

NAIPGGPKF

8.76

-4.27

-1.77

NNAIPGGPK

10.42

-2.43

0.07

LFFDPSLNP

12.06

-2.80

-0.30

P40523

LAPPPHGPF

11.85

-5.28

-2.78

LGAPPGTVP

11.92

-4.91

-2.41

HNSPRNPDT

12.81

-2.38

0.12

P53094

SAFPQSPIR

11.39

-3.33

-0.83

FPQSPIRAY

12.77

-5.14

-2.64

LKLPPLPLT

12.98

-4.87

-2.37

P37370

RPHMPSVRP

9.34

-7.64

-5.14

KVPQNRPHM

9.83

-5.87

-3.37

VSQMPKPRP

10.43

-6.02

-3.52

P39743

NATIPEDNP

12.96

-2.98

-0.48

YSNPLTSPV

14.40

-3.81

-1.31

 


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