ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1ZUY-15.PDB
Scoring matrix: MYO3_1ZUY-15_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.7
Foldx random average score for Saccharomyces cerevisiae: 14.630

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1525799
Proteins after disorder filtering: 4228
 Total fragments: 45100
Proteins after pattern filtering: 1496
 Total fragments: 3708
Proteins after MINT filtering: 19
 Total fragments: 79

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.70

4.26

0.00

Best peptides

RGFRIRLTR

0.00

-1.06

-5.32

         
Interactors      
P47068

PEPISPETK

10.22

-1.28

-5.54

PHVPSLTNR

12.14

0.30

-3.96

PSSNPFFRK

12.56

0.83

-3.43

P39113

RGPRRPQKN

9.40

-1.31

-5.57

HRGPRRPQK

9.87

-0.64

-4.90

PRRPQKNRY

12.14

0.67

-3.59

Q01389

KRSKPLPPQ

11.73

-1.88

-6.14

SGRRYPQTP

12.38

-0.26

-4.52

RYPQTPSYY

12.63

0.30

-3.96

P04050

PGSPAYSPK

13.88

0.58

-3.68

PAYSPKQDE

14.56

2.03

-2.23

P40523

PGTVPNMQM

10.98

-2.64

-6.90

NSPRNPDTG

12.79

2.26

-2.00

LAPPPHGPF

14.44

-0.46

-4.72

P38237

NFQIPSKPE

14.10

-0.52

-4.78

FQIPSKPEN

14.28

1.41

-2.85

P40450

SSPKLFPRL

11.64

-0.53

-4.79

PKLFPRLSS

13.19

-0.12

-4.38

SSSPKLFPR

14.07

0.85

-3.41

P40453

WKPPDLPIR

10.92

-0.73

-4.99

PDLPIRLRK

11.65

1.29

-2.97

KVPEPPSWK

12.77

-0.66

-4.92

P38822

PAPEVPPPR

14.07

0.11

-4.15

P53094

NVPLPPQTR

10.25

-3.36

-7.62

PQSPIRAYG

13.67

-0.08

-4.34

SAFPQSPIR

13.72

0.45

-3.81

Q04439

NIPTPPQNR

10.73

-3.09

-7.35

PSSKPKEPM

12.06

-1.30

-5.56

PSPPTAATR

13.66

0.50

-3.76

P37370

KVPQNRPHM

9.00

-1.69

-5.95

PKPRPFQNK

9.21

-2.43

-6.69

NRPHMPSVR

9.70

-0.24

-4.50

P40021

NYVISPNLP

13.36

-2.96

-7.22

FLPSTPSQM

14.12

-0.01

-4.27

ISPNLPTTI

14.33

0.79

-3.47

Q12446

PQLPNRNNR

9.42

-0.69

-4.95

PFPVPQQQF

11.76

-0.45

-4.71

PAPPPPPRR

13.17

-0.91

-5.17

Q08989

NGDHPKGPP

13.87

-1.09

-5.35

Q08912

HGDHPKGPP

13.66

-0.59

-4.85

P17555

SGPPPRPKK

10.20

-1.16

-5.42

PRPKKPSTL

11.24

-0.71

-4.97

P33334

GGPKFEPLY

12.77

0.10

-4.16

NNAIPGGPK

13.25

0.64

-3.62

PGGPKFEPL

13.39

-0.13

-4.39

P25604

PKPKSPHLK

12.04

-1.49

-5.75

KSPHLKPPL

12.26

-1.24

-5.50

 


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