ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-7.PDB
Scoring matrix: MYO3_1YP5-7_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.26
Foldx random average score for Saccharomyces cerevisiae: 9.839

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1344922
Proteins after disorder filtering: 4458
 Total fragments: 52928
Proteins after pattern filtering: 2070
 Total fragments: 9838
Proteins after MINT filtering: 24
 Total fragments: 497

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

12.26

3.85

0.00

Best peptides

YFPIPPWW

0.00

-2.93

-6.78

         
Interactors      
P39113

RGPRRPQK

6.61

-1.82

-5.67

PPPPPHKD

7.97

-1.63

-5.48

HRGPRRPQ

8.01

-0.14

-3.99

P25604

LPPPPPPQ

6.30

-2.93

-6.78

LPPKPNTQ

7.31

-2.79

-6.64

KPKSPHLK

7.44

-0.82

-4.67

P38822

PEVPPPRR

7.40

-2.80

-6.65

APEVPPPR

7.60

-2.39

-6.24

P40341

PPPKPPLN

7.08

-2.95

-6.80

PPPPPPPK

7.47

-2.15

-6.00

KPPLNDPS

7.67

0.40

-3.45

Q08912

PPPPPPPD

8.05

-1.59

-5.44

YTPSWGPS

8.35

1.01

-2.84

PPPPPDEK

8.45

-0.50

-4.35

P17555

APPPPPPA

7.52

-1.76

-5.61

RPKKPSTL

7.80

-0.94

-4.79

KSGPPPRP

8.39

-3.24

-7.09

Q12342

KAPPPPPP

8.90

-2.66

-6.51

P47068

VPPVPPVS

7.24

-2.26

-6.11

RAPPVPPA

7.34

-0.12

-3.97

TAPPLPRA

7.62

-0.75

-4.60

P04050

PPVRPSIS

7.88

-2.27

-6.12

LPVPPPPV

7.88

-1.77

-5.62

PVPPPPVR

8.37

-1.65

-5.50

P40450

PPPPPLPQ

7.61

-1.81

-5.66

PPPLPDLF

8.08

-1.40

-5.25

PPPPPPPL

8.14

-1.54

-5.39

P40453

VPEPPSWK

4.99

-2.95

-6.80

RPPPPPPV

6.67

-1.46

-5.31

KPPDLPIR

6.71

0.09

-3.76

P41832

PPPPPPMA

6.73

-2.60

-6.45

PPPVPAKL

7.74

-1.81

-5.66

PPPPPPPM

7.83

-1.89

-5.74

P38237

PFVPPPNV

7.91

-0.71

-4.56

PPNVPKKD

8.11

-2.73

-6.58

PPPNVPKK

8.44

-0.18

-4.03

P53094

YPLKLPPL

6.02

-1.09

-4.94

KLPPLPLT

6.07

-0.72

-4.57

AFPQSPIR

7.06

-0.56

-4.41

Q01389

YPQTPSYY

6.18

-1.84

-5.69

RSKPLPPQ

6.91

-1.14

-4.99

KPLPPQLL

6.95

-0.91

-4.76

P40021

PLPPPARS

7.00

-2.32

-6.17

SPPLPPPA

7.55

-1.58

-5.43

PPPLPPPL

7.84

-1.84

-5.69

Q04439

KPAPPPPG

6.07

-2.50

-6.35

KPKEPMFE

6.47

-1.97

-5.82

APPPPGMQ

7.11

-2.38

-6.23

Q12446

VPPPPPMR

5.46

-2.63

-6.48

PFPVPQQQ

6.28

-2.15

-6.00

APPPPPRR

6.31

-2.82

-6.67

Q01560

YYPPPPPG

4.13

-2.13

-5.98

YPPPPPGE

6.43

-0.76

-4.61

HHQPPEPQ

7.87

-0.80

-4.65

P00950

VPPPPIDA

8.12

-0.85

-4.70

FDVPPPPI

8.39

-1.03

-4.88

DVPPPPID

8.62

-0.14

-3.99

P33334

MPTRFPPA

6.18

-3.04

-6.89

PPPPPGFE

7.61

-1.66

-5.51

PPPPPPPG

7.63

-2.66

-6.51

P40523

VTPQPPSA

7.47

-0.96

-4.81

PGTVPNMQ

7.99

-2.23

-6.08

PVGVPPLA

8.22

-1.49

-5.34

Q08989

PPPPPPPD

8.05

-1.59

-5.44

PPPPDEKG

8.13

-0.65

-4.50

PPPPPDEK

8.45

-0.50

-4.35

P37370

MPKPRPFQ

5.52

-3.77

-7.62

KSPPPPPS

6.28

-1.70

-5.55

RPHMPSVR

6.61

-2.42

-6.27

 


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