ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-29.PDB
Scoring matrix: MYO3_1YP5-29_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.7
Foldx random average score for Saccharomyces cerevisiae: 12.555

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1277673
Proteins after disorder filtering: 3956
 Total fragments: 45572
Proteins after pattern filtering: 2045
 Total fragments: 11875
Proteins after MINT filtering: 25
 Total fragments: 599

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.70

0.09

0.00

Best peptides

KRPPRPPWMH

0.00

-11.08

-11.17

         
Interactors      
P39113

PRRPQKNRYN

7.76

-4.81

-4.90

RGPRRPQKNR

7.85

-5.96

-6.05

HRGPRRPQKN

7.90

-4.97

-5.06

P36150

PIVVNPSSPS

12.50

-3.98

-4.07

P38822

PAPEVPPPRR

9.72

-5.76

-5.85

APEVPPPRRS

11.03

-4.00

-4.09

DRGPAPEVPP

11.88

-4.99

-5.08

P40341

PPPPKPPLND

8.48

-6.76

-6.85

PKPPLNDPSN

9.82

-5.66

-5.75

PPPPPPPPPK

10.52

-6.42

-6.51

Q08912

KGPPPPPPPD

11.18

-5.55

-5.64

DHPKGPPPPP

11.81

-6.07

-6.16

PPPPPPDEKD

11.85

-4.41

-4.50

P17555

GPPPRPKKPS

6.60

-7.23

-7.32

PRPKKPSTLK

8.71

-7.23

-7.32

SKSGPPPRPK

9.82

-6.38

-6.47

P25604

NTPPLPPKPK

6.61

-7.73

-7.82

QAPSLPPKPN

7.63

-7.20

-7.29

PLPPKPKSPH

7.92

-7.51

-7.60

P47068

PLPPVSEEYH

8.83

-3.95

-4.04

LPPHVPSLTN

9.01

-6.10

-6.19

VDPSSNPFFR

9.16

-5.64

-5.73

P04050

PPPVRPSISF

7.75

-6.19

-6.28

PVPPPPVRPS

8.45

-7.02

-7.11

TCLPVPPPPV

9.30

-6.16

-6.25

P40450

APPPLPDLFK

6.42

-8.72

-8.81

KLPQLPPPPP

8.33

-8.30

-8.39

SPKLFPRLSS

8.93

-5.21

-5.30

P40453

KPPDLPIRLR

6.77

-9.33

-9.42

PDLPIRLRKR

8.04

-6.73

-6.82

RLRKRPPPPP

8.14

-7.03

-7.12

P41832

VIPPAPPMMP

8.26

-7.95

-8.04

ETPPPPPLPS

8.93

-7.45

-7.54

PPPPPMALFG

9.46

-5.97

-6.06

Q12342

KAPPPPPPPP

11.63

-6.16

-6.25

APPPPPPPPP

11.77

-6.61

-6.70

P38237

QIPSKPENTV

8.36

-6.05

-6.14

ENFQIPSKPE

9.63

-6.60

-6.69

NDPFVPPPNV

10.01

-5.21

-5.30

P53094

YPLKLPPLPL

7.33

-7.82

-7.91

KLPPLPLTSD

8.17

-6.45

-6.54

PPPPCPAMST

9.00

-6.10

-6.19

Q01389

RYPQTPSYYY

7.04

-7.83

-7.92

STPSRPVPPD

8.17

-5.82

-5.91

ASPSYPSIFR

8.43

-6.80

-6.89

P40021

FLPSTPSQMN

7.72

-8.34

-8.43

PPPPLPPPLF

9.10

-7.82

-7.91

NYVISPNLPT

9.42

-5.97

-6.06

Q04439

SKPKEPMFEA

9.84

-6.00

-6.09

SSKPKEPMFE

10.04

-4.40

-4.49

NIPTPPQNRD

10.44

-6.87

-6.96

Q12446

SLPPLPNQFA

5.90

-9.05

-9.14

PLPQLPNRNN

6.76

-7.89

-7.98

PPPPRASRPT

7.43

-6.63

-6.72

Q01560

PQPYYPPPPP

9.01

-7.00

-7.09

HQPPEPQPYY

9.18

-5.33

-5.42

PPPPPGEHMH

10.31

-6.95

-7.04

P00950

RSFDVPPPPI

10.78

-6.00

-6.09

DVPPPPIDAS

12.44

-4.37

-4.46

PPPPIDASSP

12.53

-4.71

-4.80

P33334

FDPSLNPIPH

8.48

-4.89

-4.98

KMPTRFPPAV

8.67

-7.95

-8.04

PPPPPPSNFE

9.20

-6.69

-6.78

P40523

GVPPLAPPPH

9.48

-7.59

-7.68

APPPHGPFST

10.56

-5.56

-5.65

APPGTVPNMQ

10.79

-5.94

-6.03

Q08989

GPPPPPPPPD

10.93

-6.32

-6.41

DHPKGPPPPP

11.81

-6.07

-6.16

PPPPPPDEKG

11.84

-4.82

-4.91

P37370

AAPPLPTFSA

7.43

-7.56

-7.65

SQMPKPRPFQ

7.66

-6.87

-6.96

PPPPLPAAMS

8.04

-7.95

-8.04

 


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