ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-26.PDB
Scoring matrix: MYO3_1YP5-26_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 13.15
Foldx random average score for Saccharomyces cerevisiae: 10.492

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1359709
Proteins after disorder filtering: 4424
 Total fragments: 81916
Proteins after pattern filtering: 2269
 Total fragments: 18952
Proteins after MINT filtering: 25
 Total fragments: 986

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

13.15

-0.71

0.00

Best peptides

DRRKRMPPW

0.00

-6.32

-5.61

         
Interactors      
P39113

GAPPPPPHK

5.20

-5.91

-5.20

PRRPQKNRY

5.50

-6.33

-5.62

HRGPRRPQK

5.86

-6.86

-6.15

P25604

KSPHLKPPL

4.78

-5.47

-4.76

LPPKPKSPH

4.84

-5.32

-4.61

KPPLPPPPP

5.56

-6.26

-5.55

P38822

PAPEVPPPR

6.12

-5.78

-5.07

GPAPEVPPP

7.35

-5.93

-5.22

APEVPPPRR

7.84

-4.06

-3.35

P40341

PPPPPPPPK

4.62

-6.53

-5.82

PPPPPKPPL

4.85

-6.99

-6.28

IPPPPPPPP

5.52

-6.85

-6.14

Q08912

DHPKGPPPP

4.92

-7.09

-6.38

KGPPPPPPP

4.99

-7.15

-6.44

PPPPDEKDR

6.77

-5.45

-4.74

P17555

SGPPPRPKK

3.23

-6.39

-5.68

PPRPKKPST

5.10

-6.26

-5.55

PAPPPPPPA

6.31

-6.00

-5.29

Q12342

KAPPPPPPP

5.01

-7.11

-6.40

PPPPPPPPP

5.78

-7.07

-6.36

APPPPPPPP

5.82

-6.83

-6.12

P47068

TLPPHVPSL

4.89

-5.97

-5.26

SIPPVPPTP

5.77

-6.11

-5.40

SAPPVPPAP

5.81

-5.95

-5.24

P04050

PPPPVRPSI

5.30

-6.52

-5.81

TCLPVPPPP

7.11

-6.06

-5.35

VPPPPVRPS

7.18

-5.77

-5.06

P40450

LPPPPPPPP

5.44

-7.15

-6.44

SSPKLFPRL

5.66

-4.67

-3.96

QLPPPPPPP

5.67

-6.87

-6.16

P40453

RLRKRPPPP

4.17

-6.40

-5.69

RKRPPPPPP

4.35

-8.56

-7.85

EIPPPLPPK

4.46

-7.88

-7.17

P41832

PPPPPVPAK

4.90

-6.76

-6.05

PPPPPPPPM

5.14

-6.15

-5.44

SQPPPPPPP

5.20

-6.77

-6.06

P38237

VPPPNVPKK

5.13

-6.38

-5.67

FVPPPNVPK

7.07

-4.53

-3.82

NDPFVPPPN

7.12

-5.45

-4.74

P53094

EPPPPCPAM

5.10

-6.27

-5.56

SAFPQSPIR

6.72

-4.64

-3.93

TREPNEPPP

6.81

-4.54

-3.83

Q01389

SSPPPIPKT

5.90

-6.33

-5.62

RSKPLPPQL

6.17

-6.58

-5.87

EEAPTKPNP

6.24

-7.78

-7.07

P40021

SPPLPPPAR

4.63

-5.96

-5.25

PPPPLPPPL

5.99

-5.84

-5.13

PPPLPPPLF

6.06

-5.29

-4.58

Q04439

SSKPKEPMF

4.62

-4.60

-3.89

SKKPAPPPP

5.40

-5.71

-5.00

IPPPPPPPP

5.52

-6.85

-6.14

Q12446

PAPPPPPRR

4.62

-6.55

-5.84

PAPPPPPHR

4.72

-6.25

-5.54

PPPPPRASR

5.16

-5.72

-5.01

Q01560

EPQPYYPPP

6.71

-6.30

-5.59

SAPQEPPAP

6.86

-4.96

-4.25

PPPPGEHMH

6.94

-5.67

-4.96

P00950

DVPPPPIDA

6.71

-4.93

-4.22

RSFDVPPPP

7.98

-4.37

-3.66

SFDVPPPPI

8.60

-3.31

-2.60

P33334

SKMPTRFPP

4.67

-6.93

-6.22

TLPPPPPPP

5.05

-6.75

-6.04

GLPPPPPGF

5.26

-6.26

-5.55

P40523

VPPLAPPPH

5.75

-5.33

-4.62

GVPPLAPPP

7.16

-6.03

-5.32

LAPPPHGPF

7.33

-4.71

-4.00

Q08989

DHPKGPPPP

4.92

-7.09

-6.38

KGPPPPPPP

4.99

-7.15

-6.44

GPPPPPPPP

5.90

-6.72

-6.01

P37370

KVPQNRPHM

4.86

-5.39

-4.68

QNRPHMPSV

5.00

-6.34

-5.63

KSPPPPPSP

5.07

-6.85

-6.14

P39743

SNPLTSPVA

8.16

-3.99

-3.28

YSNPLTSPV

10.25

-3.15

-2.44

 


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