ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-23.PDB
Scoring matrix: MYO3_1YP5-23_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.63
Foldx random average score for Saccharomyces cerevisiae: 8.792

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1530180
Proteins after disorder filtering: 4734
 Total fragments: 89165
Proteins after pattern filtering: 2261
 Total fragments: 14437
Proteins after MINT filtering: 26
 Total fragments: 911

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.63

-0.84

0.00

Best peptides

WPLHPWY

0.00

-4.58

-3.74

         
Interactors      
P39113

FTHPEGP

5.84

-4.30

-3.46

APPPPPH

6.00

-0.67

0.17

PPPPPHK

6.20

-3.61

-2.77

P36150

VVNPSSP

8.06

-2.48

-1.64

P38822

PEVPPPR

6.64

-4.29

-3.45

APEVPPP

7.29

-1.96

-1.12

PAPEVPP

7.74

-1.77

-0.93

P40341

RNIPPPP

5.46

-4.78

-3.94

PPPPPPK

5.77

-2.70

-1.86

PPPPPKP

5.77

-1.64

-0.80

Q08912

PPPPPPP

5.93

-3.82

-2.98

KGPPPPP

6.17

-3.91

-3.07

PPPPDEK

6.71

-1.66

-0.82

P17555

SGPPPRP

5.40

-2.56

-1.72

PPRPKKP

5.79

-3.57

-2.73

PPPRPKK

5.97

-3.15

-2.31

P25604

PPLPPKP

4.43

-2.73

-1.89

PPLPPPP

4.60

-5.19

-4.35

TPPLPPK

4.72

-3.27

-2.43

P47068

PPLPRAP

5.27

-1.88

-1.04

RAPPVPP

5.48

-1.60

-0.76

YVPPGIP

5.83

-2.65

-1.81

P04050

TCLPVPP

5.30

-3.45

-2.61

LPVPPPP

5.90

-3.27

-2.43

PPPPVRP

6.09

-3.38

-2.54

P40450

SPKLFPR

5.06

-2.99

-2.15

PPLPESL

5.14

-5.00

-4.16

PQLPPPP

5.24

-4.96

-4.12

P40453

WKPPDLP

4.50

-5.11

-4.27

RKRPPPP

4.62

-3.62

-2.78

RPPPPPP

4.63

-4.33

-3.49

P41832

TPPPPPL

5.13

0.60

1.44

PPAPPMM

5.20

-3.80

-2.96

SPAPPPP

5.55

-2.35

-1.51

Q12342

PPPPPPP

5.93

-3.82

-2.98

KAPPPPP

6.02

-3.80

-2.96

APPPPPP

6.58

-2.72

-1.88

P38237

FQIPSKP

5.44

-5.01

-4.17

FPEPEVP

5.79

-3.44

-2.60

PPNVPKK

6.20

-2.23

-1.39

P53094

LKLPPLP

4.04

-4.77

-3.93

YPLKLPP

4.48

-3.25

-2.41

PLKLPPL

6.14

-3.19

-2.35

Q01389

KPLPPQL

4.53

-4.50

-3.66

SPPPIPK

5.30

-2.54

-1.70

RSKPLPP

5.32

-3.51

-2.67

P40021

PPLPPPL

4.63

-1.86

-1.02

SPPLPPP

4.88

-3.12

-2.28

LPPPLFP

5.22

-3.43

-2.59

Q04439

SKKPAPP

5.58

-2.45

-1.61

SKPKEPM

5.71

-1.87

-1.03

IPPPPPP

5.79

-3.30

-2.46

Q12446

RPLPQLP

3.60

-4.99

-4.15

FPIPEIP

4.50

-4.87

-4.03

FAPLPDP

4.95

-4.13

-3.29

Q01560

YYPPPPP

5.30

-2.95

-2.11

PEPQPYY

5.55

-2.82

-1.98

SAPQEPP

6.15

-2.19

-1.35

P00950

FDVPPPP

5.05

-4.46

-3.62

VPPPPID

7.48

-1.86

-1.02

DVPPPPI

8.01

-2.16

-1.32

P33334

FTLPPPP

3.70

-5.55

-4.71

TFLPPPP

4.17

-3.61

-2.77

SGLPPPP

4.33

-1.37

-0.53

P40523

TPLPTPV

5.38

-2.93

-2.09

PLAPPPH

6.38

-1.21

-0.37

PPLAPPP

6.46

-3.48

-2.64

Q08989

PPPPPPP

5.93

-3.82

-2.98

KGPPPPP

6.17

-3.91

-3.07

PPPPDEK

6.71

-1.66

-0.82

P37370

PPLPAAM

5.09

-0.38

0.46

SPAPPLP

5.24

-2.52

-1.68

APLPPPP

5.24

-3.72

-2.88

P39743

SNPLTSP

6.35

-2.78

-1.94

TIPEDNP

7.68

-0.78

0.06

 


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