ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1YP5-10.PDB
Scoring matrix: MYO3_1YP5-10_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.39
Foldx random average score for Saccharomyces cerevisiae: 12.616

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1556105
Proteins after disorder filtering: 4805
 Total fragments: 114563
Proteins after pattern filtering: 2250
 Total fragments: 11500
Proteins after MINT filtering: 26
 Total fragments: 539

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.39

2.91

0.00

Best peptides

RKRKGMRH

0.00

-6.20

-9.11

         
Interactors      
P39113

MSPLGAPP

9.47

-2.47

-5.38

THPEGPNC

10.03

-1.63

-4.54

RGPRRPQK

10.28

-2.79

-5.70

P36150

VVNPSSPS

12.05

0.23

-2.68

P38822

PEVPPPRR

10.32

-1.64

-4.55

RGPAPEVP

12.15

-1.95

-4.86

P40341

PPPKPPLN

10.38

-2.56

-5.47

RNIPPPPP

10.59

-1.32

-4.23

KPPLNDPS

10.75

-0.64

-3.55

Q08912

TPSWGPSP

9.12

-2.39

-5.30

DHPKGPPP

9.29

-2.97

-5.88

PPPPDEKD

10.99

-0.82

-3.73

P17555

PKKPSTLK

8.20

-2.33

-5.24

RPKKPSTL

8.25

-3.69

-6.60

PPPRPKKP

10.44

-3.42

-6.33

P25604

PKPKSPHL

6.35

-3.50

-6.41

PPKPNTQL

10.08

0.17

-2.74

LPPKPKSP

10.08

-2.89

-5.80

P47068

YVPPGIPT

8.19

-1.60

-4.51

FVDPSSNP

8.95

-0.82

-3.73

MPFVDPSS

9.53

-0.66

-3.57

P04050

VSSPGFSP

9.46

-1.59

-4.50

PTSPGYSP

10.06

-1.63

-4.54

YSPTSPNY

10.07

-0.28

-3.19

P40450

PPLPNGLL

9.87

0.25

-2.66

PPLPDLFK

9.90

0.64

-2.27

SPKLFPRL

10.38

-1.76

-4.67

P40453

CPRCGPTA

8.46

-1.94

-4.85

RKRPPPPP

8.62

-3.98

-6.89

LRKRPPPP

9.87

-2.74

-5.65

P41832

PPLPSVLS

10.00

-1.39

-4.30

PPAPPMMP

10.79

-2.71

-5.62

VIPPAPPM

10.89

-1.56

-4.47

Q12342

LETPSTPS

11.35

-0.02

-2.93

AKAPPPPP

11.91

-0.83

-3.74

KAPPPPPP

12.60

-0.61

-3.52

P38237

FQIPSKPE

9.47

-0.27

-3.18

NFQIPSKP

10.52

-1.57

-4.48

IPSKPENT

10.78

-2.64

-5.55

P53094

AFPQSPIR

9.14

-1.95

-4.86

FPQSPIRA

9.87

-1.98

-4.89

YPLKLPPL

9.88

-2.67

-5.58

Q01389

KRSKPLPP

9.85

-1.69

-4.60

IPSPSSSP

9.86

-1.74

-4.65

PSYPSIFR

10.08

-0.34

-3.25

P40021

PLFPSSST

10.43

-1.45

-4.36

PLPPPARS

10.93

-1.86

-4.77

PSTPSQMN

11.01

-1.27

-4.18

Q04439

PPPPGMQN

8.20

-3.52

-6.43

SKKPAPPP

9.70

-1.62

-4.53

PPPPSSKP

9.76

-2.86

-5.77

Q12446

PPRRGPAP

7.09

-4.31

-7.22

RRGPAPPP

8.07

-2.66

-5.57

PPPPAFLT

9.79

-2.48

-5.39

Q01560

PPPPGEHM

7.37

-4.38

-7.29

EPPQAPDA

10.13

-1.43

-4.34

PPSNAPIY

10.39

-1.21

-4.12

P00950

VPPPPIDA

12.22

-0.67

-3.58

P33334

PPPPGLDE

8.29

-3.21

-6.12

FFDPSLNP

8.63

-1.39

-4.30

PPPPGFEE

8.94

-2.92

-5.83

P40523

PPPHGPFS

8.45

-3.22

-6.13

GAPPGTVP

9.79

-2.02

-4.93

NSPRNPDT

9.80

1.80

-1.11

Q08989

DHPKGPPP

9.29

-2.97

-5.88

PPPPDEKG

11.00

-0.27

-3.18

PPPPPPDE

11.85

-1.45

-4.36

P37370

RPHMPSVR

7.81

-5.51

-8.42

PPIPGAVP

8.06

-3.60

-6.51

PPPPGAFS

8.35

-3.19

-6.10

P39743

NPLTSPVA

10.53

0.48

-2.43

YSNPLTSP

11.96

0.43

-2.48

 


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