ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1VA7-23.PDB
Scoring matrix: MYO3_1VA7-23_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.52
Foldx random average score for Saccharomyces cerevisiae: 10.730

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1436225
Proteins after disorder filtering: 4602
 Total fragments: 61969
Proteins after pattern filtering: 1845
 Total fragments: 6020
Proteins after MINT filtering: 19
 Total fragments: 206

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.52

-0.69

0.00

Best peptides

RPLFPWH

0.00

-4.49

-3.80

         
Interactors      
Q12446

LPQLPNR

6.63

-4.66

-3.97

TNPFPFP

7.87

-2.36

-1.67

PPQMPAT

7.90

-3.78

-3.09

P47068

APPLPRA

9.20

-3.02

-2.33

LPPHVPS

9.25

-2.42

-1.73

PSSNPFF

9.54

-1.92

-1.23

P39113

RGPRRPQ

7.94

-2.82

-2.13

GPRRPQK

8.49

-3.40

-2.71

MSPLGAP

9.97

-2.86

-2.17

Q01389

FPNLTPN

8.03

-3.50

-2.81

SPSYPSI

8.29

-1.81

-1.12

KPLPPQL

8.50

-4.24

-3.55

P04050

SPAYSPK

7.97

-2.30

-1.61

PPVRPSI

8.21

-2.37

-1.68

SPNYSPT

8.67

-2.16

-1.47

P40523

PPPHGPF

8.34

-0.77

-0.08

PPLAPPP

9.15

-2.95

-2.26

NSPRNPD

9.83

-1.37

-0.68

P38237

NDPFVPP

8.88

-1.63

-0.94

PPPNVPK

9.27

-2.62

-1.93

PPNVPKK

9.68

-2.79

-2.10

P40450

PKLFPRL

4.18

-3.22

-2.53

PPPLPDL

7.97

-2.78

-2.09

LPQLPPP

8.33

-2.43

-1.74

P40453

PPPLPPK

7.01

-3.74

-3.05

PPDLPIR

8.43

-3.85

-3.16

PPLPPKI

8.49

-3.71

-3.02

P53094

YPLKLPP

7.09

-4.07

-3.38

PLKLPPL

8.03

-3.71

-3.02

LPPLPLT

8.14

-3.14

-2.45

P41832

PPMMPAS

7.61

-4.37

-3.68

PPPLPSV

8.65

-3.14

-2.45

IPPAPPM

9.61

-2.62

-1.93

P40021

PPLFPSS

5.59

-3.83

-3.14

HPPNHPH

8.97

-1.45

-0.76

PPLPPPL

9.01

-3.84

-3.15

Q04439

KPKEPMF

6.91

-2.26

-1.57

SKPKEPM

9.73

-1.73

-1.04

PSSKPKE

9.82

-1.84

-1.15

P37370

RPHMPSV

6.91

-3.96

-3.27

PSINPPK

7.60

-3.66

-2.97

PQNRPHM

8.15

-2.47

-1.78

P40341

PPPKPPL

8.74

-1.79

-1.10

PPLNDPS

8.95

-3.56

-2.87

KPPLNDP

9.07

-3.36

-2.67

Q01560

QPYYPPP

8.50

-1.32

-0.63

PQPYYPP

9.62

-0.92

-0.23

PEPQPYY

10.05

-3.08

-2.39

P17555

PPPRPKK

6.33

-3.06

-2.37

RPKKPST

8.24

-2.64

-1.95

PRPKKPS

10.41

-1.62

-0.93

P33334

GPKFEPL

7.81

-1.79

-1.10

PTRFPPA

7.85

-3.96

-3.27

PSLNPIP

9.30

-2.76

-2.07

P25604

TPPLPPK

6.85

-4.07

-3.38

PHLKPPL

6.96

-3.77

-3.08

KPPLPPP

7.99

-3.31

-2.62

 


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