ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1VA7-11.PDB
Scoring matrix: MYO3_1VA7-11_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.15
Foldx random average score for Saccharomyces cerevisiae: 10.073

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1423808
Proteins after disorder filtering: 4671
 Total fragments: 77070
Proteins after pattern filtering: 2045
 Total fragments: 7927
Proteins after MINT filtering: 25
 Total fragments: 333

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.15

1.46

0.00

Best peptides

RKWMPPR

0.00

-4.30

-5.76

         
Interactors      
P39113

RGPRRPQ

7.11

-4.69

-6.15

PLGAPPP

8.33

-3.55

-5.01

GAPPPPP

8.50

-3.77

-5.23

P25604

PKSPHLK

5.87

-2.22

-3.68

PLPPKPK

5.92

-3.51

-4.97

PLPPPPP

7.53

-4.84

-6.30

P38822

PEVPPPR

4.81

-5.01

-6.47

PTTTPGS

10.07

-2.56

-4.02

P40341

RNIPPPP

5.95

-6.90

-8.36

NIPPPPP

7.83

-2.93

-4.39

PSNPVSK

8.71

-0.89

-2.35

Q08912

PKGPPPP

7.73

-3.87

-5.33

KGPPPPP

7.86

-4.42

-5.88

YTPSWGP

8.86

-2.29

-3.75

P17555

PAPPPPP

8.15

-4.43

-5.89

AAPAPPP

8.32

-3.35

-4.81

PRPKKPS

8.36

-2.95

-4.41

Q12342

KAPPPPP

7.34

-4.83

-6.29

AKAPPPP

7.49

-3.94

-5.40

P47068

TAPPLPR

6.54

-1.72

-3.18

DKVPPHP

7.41

-2.74

-4.20

PHPVPSA

7.41

-1.94

-3.40

P04050

CLPVPPP

6.27

-4.12

-5.58

PVPPPPV

8.57

-3.43

-4.89

YSPTSPG

8.72

-1.57

-3.03

P40450

QLPPPPP

6.77

-4.11

-5.57

KLPQLPP

7.64

-3.60

-5.06

PKLFPRL

7.87

-3.99

-5.45

P40453

RKRPPPP

5.27

-6.92

-8.38

KRPPPPP

6.49

-5.19

-6.65

PEPPSWK

6.87

-2.56

-4.02

P41832

SQPPPPP

7.93

-4.23

-5.69

DSPAPPP

7.97

-3.22

-4.68

PAPPPPP

8.15

-4.43

-5.89

P38237

LNDPFVP

8.67

-1.67

-3.13

PFVPPPN

8.91

-3.51

-4.97

QIPSKPE

9.67

-1.42

-2.88

P53094

EDPVSPK

5.96

-2.74

-4.20

PLKLPPL

6.79

-4.96

-6.42

NVPLPPQ

7.36

-3.46

-4.92

Q01389

SKPLPPQ

6.33

-4.67

-6.13

REAPKPP

6.93

-5.65

-7.11

SRPVPPD

7.20

-3.35

-4.81

P40021

PLPPPAR

5.06

-4.08

-5.54

PLPPPLF

7.07

-4.07

-5.53

LNSPPLP

8.18

-3.04

-4.50

Q04439

KKPAPPP

6.61

-5.19

-6.65

NIPPPPP

7.83

-2.93

-4.39

ANIPPPP

8.01

-4.29

-5.75

Q12446

RLPAPPP

5.63

-6.60

-8.06

NRPVPPP

6.30

-3.70

-5.16

RGPAPPP

6.77

-6.48

-7.94

Q01560

YYPPPPP

5.71

-5.40

-6.86

PEPQPYY

6.23

-3.48

-4.94

PQPYYPP

6.94

-2.90

-4.36

P00950

DVPPPPI

7.64

-2.34

-3.80

FDVPPPP

9.55

-5.61

-7.07

P33334

PKFEPLY

7.01

-2.98

-4.44

ALPPPPP

7.45

-4.28

-5.74

TLPPPPP

7.81

-3.75

-5.21

P40523

ITPLPTP

7.46

-3.22

-4.68

PVGVPPL

7.80

-3.48

-4.94

PLAPPPH

7.86

-3.94

-5.40

Q08989

PKGPPPP

7.73

-3.87

-5.33

KGPPPPP

7.86

-4.42

-5.88

DHPKGPP

9.23

0.35

-1.11

P37370

PSINPPK

5.73

-3.65

-5.11

QMPKPRP

5.78

-4.52

-5.98

LAPLPPP

6.20

-5.02

-6.48

P39743

SNPLTSP

9.68

-1.84

-3.30

 


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